Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-08
DOI
10.1038/s41467-020-20160-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Thermal constraints on in vivo optogenetic manipulations
- (2019) Scott F. Owen et al. NATURE NEUROSCIENCE
- Role of POMC and AgRP neuronal activities on glycaemia in mice
- (2019) Aykut Göktürk Üner et al. Scientific Reports
- Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice
- (2018) Jae Hoon Jeong et al. Scientific Reports
- Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake
- (2018) Jae Hoon Jeong et al. PLOS BIOLOGY
- Insulin regulates POMC neuronal plasticity to control glucose metabolism
- (2018) Garron T Dodd et al. eLife
- Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice
- (2018) Benjamin P. Tooke et al. Molecular Metabolism
- Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice
- (2017) Kavaljit H. Chhabra et al. Molecular Metabolism
- Cholinergic neurons in the dorsomedial hypothalamus regulate food intake
- (2017) Jae Hoon Jeong et al. Molecular Metabolism
- Brain-liver connections: role of the preautonomic PVN neurons
- (2016) James D. O'Hare et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Leptin receptor-positive and leptin receptor-negative proopiomelanocortin neurons innervate an identical set of brain structures
- (2016) Leandro B. Lima et al. BRAIN RESEARCH
- Melanocortin-4 receptor–regulated energy homeostasis
- (2016) Michael J Krashes et al. NATURE NEUROSCIENCE
- A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH
- (2016) Henning Fenselau et al. NATURE NEUROSCIENCE
- Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria
- (2015) Kavaljit H. Chhabra et al. DIABETES
- G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons
- (2015) Masoud Ghamari-Langroudi et al. NATURE
- Hypothalamic POMC neurons promote cannabinoid-induced feeding
- (2015) Marco Koch et al. NATURE
- High-performance probes for light and electron microscopy
- (2015) Sarada Viswanathan et al. NATURE METHODS
- Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis
- (2015) Marc Schneeberger et al. Cell Reports
- Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice
- (2015) Mark A. Smith et al. Cell Reports
- Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss
- (2015) Fredrick E Henry et al. eLife
- Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism
- (2015) Jae Hoon Jeong et al. Molecular Metabolism
- Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels
- (2014) Jian Qiu et al. Cell Metabolism
- MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus
- (2014) B. P. Shah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Melanocortin 4 Receptors Reciprocally Regulate Sympathetic and Parasympathetic Preganglionic Neurons
- (2013) Jong-Woo Sohn et al. CELL
- Glutamate Mediates the Function of Melanocortin Receptor 4 on Sim1 Neurons in Body Weight Regulation
- (2013) Yuanzhong Xu et al. Cell Metabolism
- Central GLP-2 Enhances Hepatic Insulin Sensitivity via Activating PI3K Signaling in POMC Neurons
- (2013) Xuemei Shi et al. Cell Metabolism
- Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively
- (2013) C. Zhan et al. JOURNAL OF NEUROSCIENCE
- Postnatal Ablation of POMC Neurons Induces an Obese Phenotype Characterized by Decreased Food Intake and Enhanced Anxiety-Like Behavior
- (2013) Yona Greenman et al. MOLECULAR ENDOCRINOLOGY
- Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice
- (2012) Eric D. Berglund et al. JOURNAL OF CLINICAL INVESTIGATION
- Obesity-programmed mice are rescued by early genetic intervention
- (2012) Viviana F. Bumaschny et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulation of GABA and Glutamate Release from Proopiomelanocortin Neuron Terminals in Intact Hypothalamic Networks
- (2012) M. S. Dicken et al. JOURNAL OF NEUROSCIENCE
- Regulation of Hepatic Glucose Uptake and Storage In Vivo
- (2012) Mary Courtney Moore et al. Advances in Nutrition
- Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis
- (2011) Jari Rossi et al. Cell Metabolism
- Deletion ofLkb1in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice
- (2011) Marc Claret et al. DIABETES
- The role of the autonomic nervous liver innervation in the control of energy metabolism
- (2010) Chun-Xia Yi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Molecular and Cellular Approaches for Diversifying and Extending Optogenetics
- (2010) Viviana Gradinaru et al. CELL
- Activation ofN-Methyl-d-aspartate (NMDA) Receptors in the Dorsal Vagal Complex Lowers Glucose Production
- (2010) Carol K. L. Lam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver
- (2010) Yong Xu et al. NATURE NEUROSCIENCE
- Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically
- (2010) S. Stanley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice
- (2009) Jian H. Li et al. DIABETES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started