JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma

The Prognostic Significance of Histone Demethylase UTX in Esophageal Squamous Cell Carcinoma

(2018) Shau-Hsuan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of the Histone H3K27 Demethylase UTX Enhances Tumor Cell Radiosensitivity

(2018) Barbara H. Rath et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

(2018) Daniela Barros-Silva et al.   Cell Death & Disease

A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97

(2018) João Ramalho-Carvalho et al.   Clinical Epigenetics

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks

(2018) Juan Bayo et al.   Cell Reports

Hypoxia and hypoxia response-associated molecular markers in esophageal cancer: A systematic review

(2017) Jurgen Peerlings et al.   METHODS

Neoadjuvant therapy for esophageal cancer

(2017) Rachit D Shah et al.   World Journal of Gastrointestinal Oncology

Esophageal Cancer

(2016) Benjamin R. Alsop et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

The impact of hypoxia and its modification of the outcome of radiotherapy

(2016) Michael R. Horsman et al.   JOURNAL OF RADIATION RESEARCH

Lysine-specific demethylase KDM3A regulates ovarian cancer stemness and chemoresistance

(2016) S Ramadoss et al.   ONCOGENE

Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy

(2016) Ludovica Morera et al.   Clinical Epigenetics

Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases

(2016) Salminen Antero et al.   Aging and Disease

KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression

(2016) Xiang Yuan et al.   NEOPLASIA

IOX1, a JMJD2A inhibitor, suppresses the proliferation and migration of vascular smooth muscle cells induced by angiotensin II by regulating the expression of cell cycle-related proteins

(2015) QI HU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Histone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma

(2015) Xiaojiang Li et al.   MEDICAL ONCOLOGY

Epigenetic regulation by histone demethylases in hypoxia

(2015) Rebecca L Hancock et al.   Epigenomics

Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia

(2015) Shaliny Ramachandran et al.   Genes

A role for XLF in DNA repair and recombination in human somatic cells

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(2014) Melina Arnold et al.   GUT

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer

(2014) Mark A. Wade et al.   NUCLEIC ACIDS RESEARCH

OpenComet: An automated tool for comet assay image analysis

(2014) Benjamin M. Gyori et al.   Redox Biology

Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

(2014) Kyle J Napier   World Journal of Gastrointestinal Oncology

Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages

(2013) T. Osawa et al.   CANCER RESEARCH

Epigenetic regulation of hypoxia-responsive gene expression: Focusing on chromatin and DNA modifications

(2013) Ya-Ping Tsai et al.   INTERNATIONAL JOURNAL OF CANCER

Oncogenic Features of PHF8 Histone Demethylase in Esophageal Squamous Cell Carcinoma

(2013) Xiujing Sun et al.   PLoS One

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

(2013) Richard J. Hopkinson et al.   Chemical Science

Evaluation of DNA Single and Double Strand Breaks in Women with Cervical Neoplasia Based on Alkaline and Neutral Comet Assay Techniques

(2012) Elva I. Cortés-Gutiérrez et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A

(2012) I. Mimura et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of histone demethylases in cancer therapy

(2012) Inga Hoffmann et al.   Molecular Oncology

Chromatin as an oxygen sensor and active player in the hypoxia response

(2011) Andrew Melvin et al.   CELLULAR SIGNALLING

Epigenetics: New Questions on the Response to Hypoxia

(2011) Joel I. Perez-Perri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The MRN complex in double-strand break repair and telomere maintenance

(2010) Brandon J. Lamarche et al.   FEBS LETTERS

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(2010) Nicholas P Campbell   WORLD JOURNAL OF GASTROENTEROLOGY

Role of Hypoxia-Inducible Factors in Epigenetic Regulation via Histone Demethylases

(2009) Jun Yang et al.   Annals of the New York Academy of Sciences

Hypoxia and Radiation Therapy: Past History, Ongoing Research, and Future Promise

(2009) Sara Rockwell et al.   CURRENT MOLECULAR MEDICINE

Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia

(2009) Xiaobo Xia et al.   GENOME BIOLOGY

Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma

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Hypoxia and Aggressive Tumor Phenotype: Implications for Therapy and Prognosis

(2008) P. Vaupel   ONCOLOGIST