Epigenetic regulation of hypoxia-responsive gene expression: Focusing on chromatin and DNA modifications

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

De-SUMOylation of CCCTC Binding Factor (CTCF) in Hypoxic Stress-induced Human Corneal Epithelial Cells

(2012) Jie Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1

(2012) Maimon E. Hubbi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A

(2012) I. Mimura et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetic reprogramming and post-transcriptional regulation during the epithelial–mesenchymal transition

(2012) Chung-Yin Wu et al.   TRENDS IN GENETICS

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential

(2011) J M Heddleston et al.   CELL DEATH AND DIFFERENTIATION

Chromatin as an oxygen sensor and active player in the hypoxia response

(2011) Andrew Melvin et al.   CELLULAR SIGNALLING

Hypoxia Increases Sirtuin 1 Expression in a Hypoxia-inducible Factor-dependent Manner

(2011) Rui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter

(2011) Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetic Regulation of Surfactant Protein A Gene (SP-A) Expression in Fetal Lung Reveals a Critical Role for Suv39h Methyltransferases during Development and Hypoxia

(2011) H. Benlhabib et al.   MOLECULAR AND CELLULAR BIOLOGY

The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH

(2011) Andrew Melvin et al.   MOLECULAR BIOLOGY OF THE CELL

Hypoxia Induces Genomic DNA Demethylation through the Activation of HIF-1  and Transcriptional Upregulation of MAT2A in Hepatoma Cells

(2011) Q. Liu et al.   MOLECULAR CANCER THERAPEUTICS

MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1

(2011) Maimon E. Hubbi et al.   MOLECULAR CELL

Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial-Mesenchymal Transition

(2011) Min-Zu Wu et al.   MOLECULAR CELL

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production

(2011) E L Bell et al.   ONCOGENE

Hypoxia-Induced Down-Regulation of Neprilysin by Histone Modification in Mouse Primary Cortical and Hippocampal Neurons

(2011) Zheng Wang et al.   PLoS One

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

(2011) C. L. Partch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-induced methylation of a pontin chromatin remodeling factor

(2011) J. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

TWIST activation by hypoxia inducible factor-1 (HIF-1): Implications in metastasis and development

(2010) Muh-Hwa Yang et al.   CELL CYCLE

Chronic Prenatal Hypoxia Induces Epigenetic Programming of PKCε Gene Repression in Rat Hearts

(2010) Andrew J. Patterson et al.   CIRCULATION RESEARCH

Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis

(2010) X. Lu et al.   CLINICAL CANCER RESEARCH

Ischemia dysregulates DNA methyltransferases andp16INK4amethylation in human colorectal cancer cells

(2010) Karolina Skowronski et al.   Epigenetics

Negative Regulation of Hypoxic Responses via Induced Reptin Methylation

(2010) Jason S. Lee et al.   MOLECULAR CELL

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Tumor-associated CpG demethylation augments hypoxia-induced effects by positive autoregulation of HIF-1α

(2010) M Koslowski et al.   ONCOGENE

Roles of Coactivators in Hypoxic Induction of the Erythropoietin Gene

(2010) Feng Wang et al.   PLoS One

Regulation of Hypoxia-Inducible Genes by PGC-1α

(2009) Jonathan Shoag et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

(2009) Yoshinori Yoshida et al.   Cell Stem Cell

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Complex Regulation of the Transactivation Function of Hypoxia-inducible Factor-1α by Direct Interaction with Two Distinct Domains of the CREB-binding Protein/p300

(2009) Jorge L. Ruas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1  Enhances Hypoxic Gene Expression and Tumor Growth

(2009) A. J. Krieg et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2AX is integral to hypoxia-driven neovascularization

(2009) Matina Economopoulou et al.   NATURE MEDICINE

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

WDR5, a complexed protein

(2009) Raymond C Trievel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

(2008) Patrick J. Pollard et al.   BIOCHEMICAL JOURNAL

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

SWI/SNF Regulates the Cellular Response to Hypoxia

(2008) Niall S. Kenneth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia induces a novel signature of chromatin modifications and global repression of transcription

(2008) Amber Buescher Johnson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Direct regulation of TWIST by HIF-1α promotes metastasis

(2008) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia

(2008) G Xenaki et al.   ONCOGENE

Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells

(2008) S H Lee et al.   ONCOGENE

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development

(2007) C. T. Griffin et al.   DEVELOPMENT