Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL

Emerging Strategies to Combat ESKAPE Pathogens in the Era of Antimicrobial Resistance: A Review

(2019) Mansura S. Mulani et al.   Frontiers in Microbiology

Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections

(2019) Alex Washburn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Large-scale identification of pathogen essential genes during coinfection with sympatric and allopatric microbes

(2019) Gina R. Lewin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA)

(2018) Sanofar Abdeen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus

(2018) Trent Kunkle et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Arrayed Transposon Mutant Library of Klebsiella pneumoniae Outbreak Strain KPNIH1

(2017) Beth Ramage et al.   JOURNAL OF BACTERIOLOGY

GroEL actively stimulates folding of the endogenous substrate protein PepQ

(2017) Jeremy Weaver et al.   Nature Communications

Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness

(2016) Sanofar Abdeen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

GroEL/ES inhibitors as potential antibiotics

(2016) Sanofar Abdeen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Replacement of GroEL in Escherichia coli by the Group II Chaperonin from the Archaeon Methanococcus maripaludis

(2016) Riddhi Shah et al.   JOURNAL OF BACTERIOLOGY

Functional Partition of Cpn60α and Cpn60β Subunits in Substrate Recognition and Cooperation with Co-chaperonins

(2016) Shijia Zhang et al.   Molecular Plant

Multiple chaperonins in bacteria—novel functions and non-canonical behaviors

(2015) C. M. Santosh Kumar et al.   CELL STRESS & CHAPERONES

Unfolded DapA forms aggregates when diluted into free solution, confounding comparison with folding by the GroEL/GroES chaperonin system

(2015) Andrew J. Ambrose et al.   FEBS LETTERS

GroEL2 of Mycobacterium tuberculosis Reveals the Importance of Structural Pliability in Chaperonin Function

(2015) Neeraja Chilukoti et al.   JOURNAL OF BACTERIOLOGY

Resources for Genetic and Genomic Analysis of Emerging Pathogen Acinetobacter baumannii

(2015) Larry A. Gallagher et al.   JOURNAL OF BACTERIOLOGY

QuickStep-Cloning: a sequence-independent, ligation-free method for rapid construction of recombinant plasmids

(2015) Pawel Jajesniak et al.   Journal of Biological Engineering

A biochemical screen for GroEL/GroES inhibitors

(2014) Steven M. Johnson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The C-terminal Tails of the Bacterial Chaperonin GroEL Stimulate Protein Folding by Directly Altering the Conformation of a Substrate Protein

(2014) Jeremy Weaver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualizing GroEL/ES in the Act of Encapsulating a Folding Protein

(2013) Dong-Hua Chen et al.   CELL

Structural and Functional Conservation of Mycobacterium tuberculosis GroEL Paralogs Suggests that GroEL1 Is a Chaperonin

(2010) Bernhard Sielaff et al.   JOURNAL OF MOLECULAR BIOLOGY

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH)

(2009) Roy R Chaudhuri et al.   BMC GENOMICS

Facilitated Oligomerization of Mycobacterial GroEL: Evidence for Phosphorylation-Mediated Oligomerization

(2009) C. M. S. Kumar et al.   JOURNAL OF BACTERIOLOGY

Requirement for binding multiple ATPs to convert a GroEL ring to the folding-active state

(2008) E. Chapman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA