Downregulation of IRAK1 Prevents the Malignant Behavior of Hepatocellular Carcinoma Cells by Blocking Activation of the MAPKs/NLRP3/IL-1β Pathway
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Downregulation of IRAK1 Prevents the Malignant Behavior of Hepatocellular Carcinoma Cells by Blocking Activation of the MAPKs/NLRP3/IL-1β Pathway
Authors
Keywords
-
Journal
OncoTargets and Therapy
Volume Volume 13, Issue -, Pages 12787-12796
Publisher
Informa UK Limited
Online
2020-12-14
DOI
10.2147/ott.s260793
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- IRAK family in inflammatory autoimmune diseases
- (2020) Lin-Chong Su et al. AUTOIMMUNITY REVIEWS
- Hepatocellular Carcinoma
- (2019) Augusto Villanueva NEW ENGLAND JOURNAL OF MEDICINE
- E2-Induced Activation of the NLRP3 Inflammasome Triggers Pyroptosis and Inhibits Autophagy in HCC Cells
- (2019) Qing Wei et al. ONCOLOGY RESEARCH
- IRAK1 Augments Cancer Stemness and Drug Resistance via the AP-1/AKR1B10 Signaling Cascade in Hepatocellular Carcinoma
- (2018) Bowie Y. Cheng et al. CANCER RESEARCH
- NLRP3 inflammasome: A likely target for the treatment of allergic diseases
- (2018) Yichen Xiao et al. CLINICAL AND EXPERIMENTAL ALLERGY
- The NLRP3 Inflammasome Renders Cell Death Pro-inflammatory
- (2018) Moritz M. Gaidt et al. JOURNAL OF MOLECULAR BIOLOGY
- Hepatocellular carcinoma
- (2018) Alejandro Forner et al. LANCET
- Role of p38/MAPKs in Alzheimer’s disease: implications for amyloid beta toxicity targeted therapy
- (2018) Ghazaleh Kheiri et al. REVIEWS IN THE NEUROSCIENCES
- Cancer secretome and inflammation: The bright and the dark sides of NF-κB
- (2018) Daria Capece et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- An unexpected friend − ROS in apoptosis-induced compensatory proliferation: Implications for regeneration and cancer
- (2018) Neha Diwanji et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
- (2018) Jack W. Singer et al. Oncotarget
- Epithelial-to-mesenchymal transition in cancer: complexity and opportunities
- (2018) Yun Zhang et al. Frontiers of Medicine
- Role of the NLRP3 inflammasome in cancer
- (2018) Maryam Moossavi et al. Molecular Cancer
- New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
- (2018) Anushka Dongre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Radiotherapy for Hepatocellular Carcinoma
- (2018) Yao Yu et al. SEMINARS IN RADIATION ONCOLOGY
- Inflammation and cancer
- (2018) Mariko Murata Environmental Health and Preventive Medicine
- Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals
- (2017) Mallenahally Kusha Vidya et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- The NLPR3 inflammasome and obesity-related kidney disease
- (2017) Ben Ke et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Epithelial-mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis
- (2017) Tong Chen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The diagnosis and treatment of hepatocellular carcinoma
- (2017) Justin Hartke et al. SEMINARS IN DIAGNOSTIC PATHOLOGY
- The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines from 2001 to 2017
- (2017) Peipei Song et al. BioScience Trends
- Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade
- (2017) Guangxi Wang et al. Scientific Reports
- Inflammasome Complexes: Emerging Mechanisms and Effector Functions
- (2016) Vijay A.K. Rathinam et al. CELL
- Targeting interleukin-1 receptor-associated kinase 1 for human hepatocellular carcinoma
- (2016) Ning Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The NLRP3 inflammasome in kidney disease and autoimmunity
- (2016) Holly L Hutton et al. NEPHROLOGY
- Compromised MAPK signaling in human diseases: an update
- (2015) Eun Kyung Kim et al. ARCHIVES OF TOXICOLOGY
- Regulation of inflammasome activation
- (2015) Si Ming Man et al. IMMUNOLOGICAL REVIEWS
- Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome
- (2015) Qing Wei et al. LABORATORY INVESTIGATION
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- Inflammation and cancer: advances and new agents
- (2015) Shanthini M. Crusz et al. Nature Reviews Clinical Oncology
- Broad targeting of resistance to apoptosis in cancer
- (2015) Ramzi M. Mohammad et al. SEMINARS IN CANCER BIOLOGY
- Invasion and metastasis-related long noncoding RNA expression profiles in hepatocellular carcinoma
- (2015) Yunzhen Gao et al. TUMOR BIOLOGY
- IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel
- (2015) Zhen Ning Wee et al. Nature Communications
- Targeting IRAK1 in T-cell acute lymphoblastic leukemia
- (2015) Charles Dussiau et al. Oncotarget
- NLRP3 inflammasome and its inhibitors: a review
- (2015) Bo-Zong Shao et al. Frontiers in Pharmacology
- Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
- (2013) T. Fernandes-Alnemri et al. JOURNAL OF IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started