The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self

The buildup of an urge in obsessive–compulsive disorder: Behavioral and neuroimaging correlates

(2020) Emily R. Stern et al.   HUMAN BRAIN MAPPING

Modulation of Body Representation Impacts on Efferent Autonomic Activity

(2020) Marco D'Alonzo et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Estimation of Current and Future Physiological States in Insular Cortex

(2020) Yoav Livneh et al.   NEURON

Interventions and Manipulations of Interoception

(2020) Helen Y. Weng et al.   TRENDS IN NEUROSCIENCES

Computational Models of Interoception and Body Regulation

(2020) Frederike H. Petzschner et al.   TRENDS IN NEUROSCIENCES

Diseases, Disorders, and Comorbidities of Interoception

(2020) Bruno Bonaz et al.   TRENDS IN NEUROSCIENCES

Functions of Interoception: From Energy Regulation to Experience of the Self

(2020) Karen S. Quigley et al.   TRENDS IN NEUROSCIENCES

Neural Circuits of Interoception

(2020) Gary G. Berntson et al.   TRENDS IN NEUROSCIENCES

The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits

(2019) Monica M. Li et al.   NEURON

Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder

(2019) Mehdi Farokhnia et al.   PHYSIOLOGY & BEHAVIOR

Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies

(2019) Pradeep S. Rajendran et al.   Nature Communications

The Organization of the Primate Insular Cortex

(2019) Henry C. Evrard   Frontiers in Neuroanatomy

An Atlas of Vagal Sensory Neurons and Their Molecular Specialization

(2019) Jussi Kupari et al.   Cell Reports

Anterior insular cortex plays a critical role in interoceptive attention

(2019) Xingchao Wang et al.   eLife

Regulation of Memory Function by Feeding-Relevant Biological Systems: Following the Breadcrumbs to the Hippocampus

(2019) Andrea N. Suarez et al.   Frontiers in Molecular Neuroscience

Visceral Signals Shape Brain Dynamics and Cognition

(2019) Damiano Azzalini et al.   TRENDS IN COGNITIVE SCIENCES

Aversive state processing in the posterior insular cortex

(2019) Daniel A. Gehrlach et al.   NATURE NEUROSCIENCE

Neurostimulation methods in the treatment of chronic pain

(2019) X. Moisset et al.   JOURNAL OF NEURAL TRANSMISSION

Habenular TCF7L2 links nicotine addiction to diabetes

(2019) Alexander Duncan et al.   NATURE

The use of stimulus perception to account for variability in skin conductance responses to interoceptive stimuli

(2019) Jonas Zaman et al.   PSYCHOPHYSIOLOGY

The mind–body problem: Circuits that link the cerebral cortex to the adrenal medulla

(2019) Richard P. Dum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress, Motivation, and the Gut-Brain Axis: A Focus on the Ghrelin System and Alcohol Use Disorder

(2018) Laurel S. Morris et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Individual differences in socioemotional sensitivity are an index of salience network function

(2018) Gianina Toller et al.   CORTEX

Proprioception

(2018) John C. Tuthill et al.   CURRENT BIOLOGY

Feel the Time. Time Perception as a Function of Interoceptive Processing

(2018) Daniele Di Lernia et al.   Frontiers in Human Neuroscience

Component network meta-analysis identifies the most effective components of psychological preparation for adults undergoing surgery under general anesthesia

(2018) Suzanne C. Freeman et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Optogenetic manipulation of ENS - The brain in the gut

(2018) Wei Wang   LIFE SCIENCES

Interoceptive inference: From computational neuroscience to clinic

(2018) Andrew P. Owens et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Gut vagal sensory signaling regulates hippocampus function through multi-order pathways

(2018) Andrea N. Suarez et al.   Nature Communications

A Neural Circuit for Gut-Induced Reward

(2018) Wenfei Han et al.   CELL

Microneurography as a tool to study the function of individual C-fiber afferents in humans: responses from nociceptors, thermoreceptors, and mechanoreceptors

(2018) Rochelle Ackerley et al.   JOURNAL OF NEUROPHYSIOLOGY

A gut-brain neural circuit for nutrient sensory transduction

(2018) Melanie Maya Kaelberer et al.   SCIENCE

Contribution of Baroreceptor Function to Pain Perception and Perioperative Outcomes

(2018) Heberto Suarez-Roca et al.   ANESTHESIOLOGY

Transcriptomic Landscape of von Economo Neurons in Human Anterior Cingulate Cortex Revealed by Microdissected-Cell RNA Sequencing

(2018) Lixin Yang et al.   CEREBRAL CORTEX

Facets of impulsivity and alcohol use: What role do emotions play?

(2018) Aleksandra M. Herman et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Heightened brain response to pain anticipation in high-functioning adults with autism spectrum disorder

(2017) Xiaosi Gu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Structure and Function of the Human Insula

(2017) Lucina Q. Uddin et al.   JOURNAL OF CLINICAL NEUROPHYSIOLOGY

Obesity is associated with altered mid-insula functional connectivity to limbic regions underlying appetitive responses to foods

(2017) Jason A Avery et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Neurobehavioral evidence of interoceptive sensitivity in early infancy

(2017) Lara Maister et al.   eLife

Significance of neuro-cardiac control mechanisms governed by higher regions of the brain

(2016) Peter Taggart et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Discrepancies between dimensions of interoception in autism: Implications for emotion and anxiety

(2016) Sarah N. Garfinkel et al.   BIOLOGICAL PSYCHOLOGY

Central Control Circuit for Context-Dependent Micturition

(2016) Xun Helen Hou et al.   CELL

Sensory Neurons that Detect Stretch and Nutrients in the Digestive System

(2016) Erika K. Williams et al.   CELL

Interoception and Positive Symptoms in Schizophrenia

(2016) Martina Ardizzi et al.   Frontiers in Human Neuroscience

Alterations in emotion generation and regulation neurocircuitry in depression and eating disorders: A comparative review of structural and functional neuroimaging studies

(2016) Shannon D. Donofry et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Role of PIEZO2 in Human Mechanosensation

(2016) Alexander T. Chesler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Feeling, learning from and being aware of inner states: interoceptive dimensions in neurodegeneration and stroke

(2016) Indira García-Cordero et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Differentiating attention styles and regulatory aspects of self-reported interoceptive sensibility

(2016) Wolf Mehling   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Towards a psychophysics of interoceptive processes: the measurement of heartbeat detection

(2016) Jasper Brener et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Threat and the Body: How the Heart Supports Fear Processing

(2016) Sarah N. Garfinkel et al.   TRENDS IN COGNITIVE SCIENCES

Vagal Sensory Neuron Subtypes that Differentially Control Breathing

(2015) Rui B. Chang et al.   CELL

Ascending parabrachio-thalamo-striatal pathways: Potential circuits for integration of gustatory and oral motor functions

(2015) H. Iwai et al.   NEUROSCIENCE

Female migraineurs show lack of insular thinning with age

(2015) Nasim Maleki et al.   PAIN

Interoceptive dysfunction: Toward an integrated framework for understanding somatic and affective disturbance in depression.

(2015) Christopher Harshaw   PSYCHOLOGICAL BULLETIN

Stroke and Neurodegeneration Induce Different Connectivity Aberrations in the Insula

(2015) Indira García-Cordero et al.   STROKE

Sensory convergence in the parieto-insular vestibular cortex

(2014) Michael E. Shinder et al.   JOURNAL OF NEUROPHYSIOLOGY

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Major Depressive Disorder Is Associated With Abnormal Interoceptive Activity and Functional Connectivity in the Insula

(2013) Jason A. Avery et al.   BIOLOGICAL PSYCHIATRY

Human von Economo Neurons Express Transcription Factors Associated with Layer V Subcerebral Projection Neurons

(2013) I. Cobos et al.   CEREBRAL CORTEX

What do you feel? Adolescent drug and alcohol users show altered brain response to pleasant interoceptive stimuli

(2013) Robyn Migliorini et al.   DRUG AND ALCOHOL DEPENDENCE

Anterior insular cortex and emotional awareness

(2013) Xiaosi Gu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Visceral Influences on Brain and Behavior

(2013) Hugo D. Critchley et al.   NEURON

Molecular anatomy of the gut-brain axis revealed with transgenic technologies: implications in metabolic research

(2013) Swalpa Udit et al.   Frontiers in Neuroscience

A convergent functional architecture of the insula emerges across imaging modalities

(2012) Clare Kelly et al.   NEUROIMAGE

Von Economo Neurons in the Anterior Insula of the Macaque Monkey

(2012) Henry C. Evrard et al.   NEURON

Transneuronal tracing of airways-related sensory circuitry using herpes simplex virus 1, strain H129

(2012) A.E. McGovern et al.   NEUROSCIENCE

Ascending projections from the caudal visceral nucleus of the solitary tract to brain regions involved in food intake and energy expenditure

(2010) Linda Rinaman   BRAIN RESEARCH

The insular cortex: a comparative perspective

(2010) Camilla Butti et al.   Brain Structure & Function

A link between the systems: functional differentiation and integration within the human insula revealed by meta-analysis

(2010) Florian Kurth et al.   Brain Structure & Function

Patients With Irritable Bowel Syndrome Have Altered Emotional Modulation of Neural Responses to Visceral Stimuli

(2010) Sigrid Elsenbruch et al.   GASTROENTEROLOGY

The Spinothalamic System Targets Motor and Sensory Areas in the Cerebral Cortex of Monkeys

(2009) R. P. Dum et al.   JOURNAL OF NEUROSCIENCE

The pathways of interoceptive awareness

(2009) Sahib S Khalsa et al.   NATURE NEUROSCIENCE

The anterior insula in autism: Under-connected and under-examined

(2009) Lucina Q. Uddin et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Interoceptive awareness declines with age

(2009) Sahib S. Khalsa et al.   PSYCHOPHYSIOLOGY

Initial Evidence of a Failure to Activate Right Anterior Insula During Affective Set Shifting in Posttraumatic Stress Disorder

(2009) Alan Simmons et al.   PSYCHOSOMATIC MEDICINE

The Neurocircuitry of Impaired Insight in Drug Addiction

(2009) Rita Z. Goldstein et al.   TRENDS IN COGNITIVE SCIENCES

How do you feel — now? The anterior insula and human awareness

(2008) A. D. (Bud) Craig   NATURE REVIEWS NEUROSCIENCE

CRFergic Innervation Of the Paraventricular Nucleus of the Rat Hypothalamus: A Tract-Tracing Study

(2003) Danielle Champagne et al.   JOURNAL OF NEUROENDOCRINOLOGY