Gestational arsenite exposure augments hepatic tumors of C3H mice by promoting senescence in F1 and F2 offspring via different pathways

Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues

(2020) Matthew J. Yousefzadeh et al.   GeroScience

A Systematic Review of the Various Effect of Arsenic on Glutathione Synthesis In Vitro and In Vivo

(2020) Shanshan Ran et al.   Biomed Research International

Revisiting Telomere Shortening in Cancer

(2019) Keiji Okamoto et al.   Cells

DNA methylation changes involved in the tumor increase in F2 males born to gestationally arsenite‐exposed F1 male mice

(2019) Kazuyuki Okamura et al.   CANCER SCIENCE

TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

(2019) Kana Tominaga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inducing and exploiting vulnerabilities for the treatment of liver cancer

(2019) Cun Wang et al.   NATURE

The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes

(2018) Junya Matsushita et al.   BMC CANCER

Epigenetics as a mechanism linking developmental exposures to long-term toxicity

(2018) R. Barouki et al.   ENVIRONMENT INTERNATIONAL

Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling

(2018) Ying Wang et al.   JOURNAL OF CELL BIOLOGY

Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice

(2018) Kan Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma

(2018) Anna Tutusaus et al.   Oncotarget

TGF-β Signaling Accelerates Senescence of Human Bone-Derived CD271 and SSEA-4 Double-Positive Mesenchymal Stromal Cells

(2018) Hiroshi Kawamura et al.   Stem Cell Reports

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

(2018) Tyler J. Bussian et al.   NATURE

The Clinical Potential of Senolytic Drugs

(2017) James L. Kirkland et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

(2016) Tobias Eggert et al.   CANCER CELL

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

TGF-β Family Signaling in the Control of Cell Proliferation and Survival

(2016) Yun Zhang et al.   Cold Spring Harbor Perspectives in Biology

Long-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells

(2015) Kazuyuki Okamura et al.   ARCHIVES OF TOXICOLOGY

Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F2male offspring via the F1male offspring

(2015) Keiko Nohara et al.   JOURNAL OF APPLIED TOXICOLOGY

Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

A Novel Therapeutic Combination Sequentially Targeting Aurora B and Bcl-xL in Hepatocellular Carcinoma

(2014) Hiroko Matsunaga et al.   ANNALS OF SURGICAL ONCOLOGY

High accumulation of arsenic in the esophagus of mice after exposure to arsenite

(2014) Daigo Sumi et al.   ARCHIVES OF TOXICOLOGY

The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells

(2014) Bin Wang et al.   Molecular Cancer

In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism

(2014) E. J. Radford et al.   SCIENCE

Aspirin overcomes Navitoclax-resistance in hepatocellular carcinoma cells through suppression of Mcl-1

(2013) Gongquan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Telomere Dynamics in Mice and Humans

(2013) Rodrigo T. Calado et al.   SEMINARS IN HEMATOLOGY

From Cirrhosis to Hepatocellular Carcinoma: New Molecular Insights on Inflammation and Cellular Senescence

(2013) Gayatri Ramakrishna et al.   Liver Cancer

Assessing Cell and Organ Senescence Biomarkers

(2012) Bruno Bernardes de Jesus et al.   CIRCULATION RESEARCH

Senescent Cells: A Novel Therapeutic Target for Aging and Age-Related Diseases

(2012) R M Naylor et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Late-onset Increases in Oxidative Stress and Other Tumorigenic Activities and Tumors With a Ha-ras Mutation in the Liver of Adult Male C3H Mice Gestationally Exposed to Arsenic

(2012) Keiko Nohara et al.   TOXICOLOGICAL SCIENCES

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Survivin Inhibition Is Critical for Bcl-2 Inhibitor-Induced Apoptosis in Hepatocellular Carcinoma Cells

(2011) Xiangxuan Zhao et al.   PLoS One

Arsenic Exposure and Toxicology: A Historical Perspective

(2011) Michael F. Hughes et al.   TOXICOLOGICAL SCIENCES

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

Kidney Cancer Mortality

(2009) Yan Yuan et al.   EPIDEMIOLOGY

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

(2008) C. Tse et al.   CANCER RESEARCH

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Statistical Modeling of Global Geogenic Arsenic Contamination in Groundwater

(2008) Manouchehr Amini et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY