PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans

High-fat feeding reprograms maternal energy metabolism and induces long-term postpartum obesity in mice

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Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications

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Diabetes & Women’s Health (DWH) Study: an observational study of long-term health consequences of gestational diabetes, their determinants and underlying mechanisms in the USA and Denmark

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Depot-specific and GH-dependent regulation of IGF binding protein-4, pregnancy-associated plasma protein-A, and stanniocalcin-2 in murine adipose tissue

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Association of Gestational Diabetes and Type 2 Diabetes Exposure In Utero With the Development of Type 2 Diabetes in First Nations and Non–First Nations Offspring

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Difference in Visceral Adipose Tissue in Pregnancy and Postpartum and Related Changes in Maternal Insulin Resistance

(2018) Shiri Shinar et al.   JOURNAL OF ULTRASOUND IN MEDICINE

Exposure to gestational diabetes is a stronger predictor of dysmetabolic traits in children than size at birth

(2018) Freja Bach Kampmann et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue

(2018) Vanessa Pellegrinelli et al.   Nature Communications

IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots

(2017) David E Maridas et al.   ENDOCRINOLOGY

Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk

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Early Pregnancy-Associated Plasma Protein A Concentrations Are Associated With Third Trimester Insulin Sensitivity

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YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

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Higher Ratio of Abdominal Subcutaneous to Visceral Adipose Tissue Related with Preservation of Islet β-Cell Function in Healthy Individuals

(2017) Juan Liu et al.   International Journal of Endocrinology

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production

(2016) Paul M. Titchenell et al.   Cell Metabolism

Evidence Supporting a Paracrine Effect of IGF-1/VEGF on Human Mesenchymal Stromal Cell Commitment

(2016) Manuela Dicarlo et al.   CELLS TISSUES ORGANS

PAPP-A, IGFBP-4 and IGF-II are secreted by human adipose tissue cultures in a depot-specific manner

(2016) Mette Faurholdt Gude et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

First trimester pregnancy-associated plasma protein-A and birth weight

(2016) Rebecca J. Baer et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Comparative gene expression and phenotype analyses of skeletal muscle from aged wild-type and PAPP-A-deficient mice

(2016) Cheryl A. Conover et al.   EXPERIMENTAL GERONTOLOGY

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

(2015) Rachel J. Perry et al.   CELL

Association Between Visceral and Subcutaneous Adipose Depots and Incident Cardiovascular Disease Risk FactorsCLINICAL PERSPECTIVE

(2015) Tobin M. Abraham et al.   CIRCULATION

Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice

(2015) Samantha L. Hocking et al.   DIABETOLOGIA

Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus

(2015) Raziel Rojas-Rodriguez et al.   DIABETOLOGIA

Body fat mass and the proportion of very large adipocytes in pregnant women are associated with gestational insulin resistance

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Correlation of neonatal weight with maternal serum levels of pregnancy-associated plasma protein-A during the first trimester of pregnancy: a retrospective study

(2015) Ivana Giudice et al.   JOURNAL OF PERINATAL MEDICINE

Serum pregnancy-associated plasma protein-A in the three trimesters of pregnancy: effects of maternal characteristics and medical history

(2015) D. Wright et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis

(2015) Shannon M. Reilly et al.   Nature Communications

Visceral, subcutaneous abdominal adiposity and liver fat content distribution in normal glucose tolerance, impaired fasting glucose and/or impaired glucose tolerance

(2014) A-L Borel et al.   INTERNATIONAL JOURNAL OF OBESITY

Control of Adipose Tissue Expandability in Response to High Fat Diet by the Insulin-like Growth Factor-binding Protein-4

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A comparative encyclopedia of DNA elements in the mouse genome

(2014) Feng Yue et al.   NATURE

Induction of adipocyte hyperplasia in subcutaneous fat depot alleviated type 2 diabetes symptoms in obese mice

(2014) Qiqi Lu et al.   Obesity

Autocrine and Paracrine Actions of IGF-I Signaling in Skeletal Development

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Preferential impact of pregnancy-associated plasma protein-A deficiency on visceral fat in mice on high-fat diet

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Adipose tissue angiogenesis: Impact on obesity and type-2 diabetes

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Gestational diabetes mellitus: Including serum pregnancy-associated plasma protein-A testing in the clinical management of primiparous women? A case–control study

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Prediction of type 2 diabetes in women with a history of gestational diabetes using a genetic risk score

(2013) Soo Heon Kwak et al.   DIABETOLOGIA

Molecular inflammation and adipose tissue matrix remodeling precede physiological adaptations to pregnancy

(2012) Veronica Resi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

First trimester maternal serum free β-human chorionic gonadotropin and pregnancy-associated plasma protein A in pregnancies complicated by diabetes mellitus

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The Insulin-Like Growth Factors in Adipogenesis and Obesity

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Association between pregnancy-associated plasma protein-A and gestational diabetes requiring insulin treatment at 11–14 weeks of gestation

(2012) Heinrich Husslein et al.   Journal of Maternal-Fetal & Neonatal Medicine

Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling

(2012) Jeremie Boucher et al.   Nature Communications

Gestational Diabetes and the Offspring: Implications in the Development of the Cardiorenal Metabolic Syndrome in Offspring

(2012) Liliana Garcia-Vargas et al.   CardioRenal Medicine

Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity

(2011) Olga Gealekman et al.   CIRCULATION

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Characterisation of non-obese diabetic patients with marked insulin resistance identifies a novel familial partial lipodystrophy-associated PPARγ mutation (Y151C)

(2011) M. E. Visser et al.   DIABETOLOGIA

First trimester pregnancy-associated plasma protein-A in pregnancies complicated by subsequent gestational diabetes

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Examination of the pregnancy-associated plasma protein-A assay on the Beckman Coulter Access® platform: suitability for use in first trimester Down's syndrome screening

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Body fat, insulin resistance, energy expenditure and serum concentrations of leptin, adiponectin and resistin before, during and after pregnancy in healthy Swedish women

(2009) Britt Eriksson et al.   BRITISH JOURNAL OF NUTRITION

Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy

(2009) Víctor A. Cortés et al.   Cell Metabolism

Abdominal Subcutaneous Adipose Tissue: A Protective Fat Depot?

(2009) S. A. Porter et al.   DIABETES CARE

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation inCIDEC

(2009) Oscar Rubio-Cabezas et al.   EMBO Molecular Medicine

Occludin Phosphorylation and Ubiquitination Regulate Tight Junction Trafficking and Vascular Endothelial Growth Factor-induced Permeability

(2009) Tomoaki Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis

(2009) Leanne Bellamy et al.   LANCET

Angiogenesis and development of adipose tissue

(2009) V. Christiaens et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors

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The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity

(2007) Yuka Ichikawa-Shindo et al.   JOURNAL OF CLINICAL INVESTIGATION