Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms
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Title
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 50, Pages 32056-32065
Publisher
Proceedings of the National Academy of Sciences
Online
2020-12-01
DOI
10.1073/pnas.2005877117
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Note: Only part of the references are listed.- Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse
- (2019) R. Filograna et al. Science Advances
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- (2017) Hyunbae Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR
- (2016) Christopher J. Fiorese et al. CURRENT BIOLOGY
- CREBH Couples Circadian Clock With Hepatic Lipid Metabolism
- (2016) Ze Zheng et al. DIABETES
- MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism
- (2015) Siddhesh Aras et al. MITOCHONDRION
- Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research
- (2015) Norman Moullan et al. Cell Reports
- CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation
- (2014) Y Liu et al. CELL DEATH AND DIFFERENTIATION
- Liver-Enriched Transcription Factor CREBH Interacts With Peroxisome Proliferator-Activated Receptor α to Regulate Metabolic Hormone FGF21
- (2014) Hyunbae Kim et al. ENDOCRINOLOGY
- Thei-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
- (2014) Ruchika Anand et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
- (2014) Mark W. Pellegrino et al. NATURE
- Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming
- (2014) M. Picard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
- (2014) Sarah J. Mitchell et al. Cell Reports
- Efficient mitochondrial biogenesis drives incomplete penetrance in Leber’s hereditary optic neuropathy
- (2013) Carla Giordano et al. BRAIN
- The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease
- (2013) V. Jovaisaite et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2
- (2013) Siddhesh Aras et al. NUCLEIC ACIDS RESEARCH
- Global Subcellular Characterization of Protein Degradation Using Quantitative Proteomics
- (2012) Mark Larance et al. MOLECULAR & CELLULAR PROTEOMICS
- Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation
- (2012) A. M. Nargund et al. SCIENCE
- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice
- (2011) Chunbin Zhang et al. HEPATOLOGY
- Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
- (2011) R. Bravo et al. JOURNAL OF CELL SCIENCE
- New mitochondrial tRNAHIS mutation in a family with lactic acidosis and stroke-like episodes (MELAS)
- (2011) Maria Antonietta Calvaruso et al. MITOCHONDRION
- Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
- (2011) Ira Tabas et al. NATURE CELL BIOLOGY
- Hypoxia and mitochondrial oxidative metabolism
- (2010) Giancarlo Solaini et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function
- (2010) Manjula Darshi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging roles of mitochondrial proteases in neurodegeneration
- (2009) Paola Martinelli et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins
- (2009) Ivy K. M. Law et al. PROTEOMICS
- Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
- (2008) Inki Kim et al. NATURE REVIEWS DRUG DISCOVERY
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