Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming
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Title
Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 38, Pages E4033-E4042
Publisher
Proceedings of the National Academy of Sciences
Online
2014-09-06
DOI
10.1073/pnas.1414028111
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- Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases
- (2013) Stephen L. Archer NEW ENGLAND JOURNAL OF MEDICINE
- Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model
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- A Systems Approach for Decoding Mitochondrial Retrograde Signaling Pathways
- (2013) S. Chae et al. Science Signaling
- Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease
- (2013) D. C. Wallace et al. Cold Spring Harbor Perspectives in Biology
- Metabolically induced heteroplasmy shifting and l-arginine treatment reduce the energetic defect in a neuronal-like model of MELAS
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- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- The Human Mitochondrial Transcriptome
- (2011) Tim R. Mercer et al. CELL
- Epigenetic Regulation of Motor Neuron Cell Death through DNA Methylation
- (2011) B. A. Chestnut et al. JOURNAL OF NEUROSCIENCE
- Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
- (2011) Christopher J Klein et al. NATURE GENETICS
- DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
- (2011) Lisa S. Shock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Energetics and Therapeutics
- (2010) Douglas C. Wallace et al. Annual Review of Pathology-Mechanisms of Disease
- Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism
- (2010) Arnaud Chevrollier et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Structure and Function of Mammalian DNA Methyltransferases
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- (2009) Da Wei Huang et al. Nature Protocols
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- (2009) K. E. Wellen et al. SCIENCE
- Pathogenic Mitochondrial DNA Mutations Are Common in the General Population
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- (2008) F. Sasarman et al. HUMAN MOLECULAR GENETICS
- Genome-scale DNA methylation maps of pluripotent and differentiated cells
- (2008) Alexander Meissner et al. NATURE
- Coupling and coordination in gene expression processes: a systems biology view
- (2007) Suzanne Komili et al. NATURE REVIEWS GENETICS
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