Oral cysteamine as an adjunct treatment in cystic fibrosis pulmonary exacerbations: An exploratory randomized clinical trial

Thiol disulfide exchange reactions in human serum albumin: the apparent paradox of the redox transitions of Cys34

(2018) Alessio Bocedi et al.   FEBS Journal

Autoinflammatory disease in the lung

(2018) Thomas Scambler et al.   IMMUNOLOGY

Standardized Treatment of Pulmonary Exacerbations (STOP) study: Physician treatment practices and outcomes for individuals with cystic fibrosis with pulmonary Exacerbations

(2017) Natalie E. West et al.   Journal of Cystic Fibrosis

Rationalizing endpoints for prospective studies of pulmonary exacerbation treatment response in cystic fibrosis

(2017) D.R. VanDevanter et al.   Journal of Cystic Fibrosis

Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages

(2017) Chandra L. Shrestha et al.   PLoS One

Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation

(2017) Eleonora Ferrari et al.   Cell Death & Disease

Activity of Cysteamine against the Cystic Fibrosis Pathogen Burkholderia cepacia Complex

(2016) Douglas Fraser-Pitt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An Open-Label Investigation of the Pharmacokinetics and Tolerability of Oral Cysteamine in Adults with Cystic Fibrosis

(2016) Graham Devereux et al.   CLINICAL DRUG INVESTIGATION

The burgeoning field of innate immune-mediated disease and autoinflammation

(2016) Daniel Peckham et al.   JOURNAL OF PATHOLOGY

Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum

(2015) Graham Devereux et al.   EBioMedicine

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

(2014) Daniela De Stefano et al.   Autophagy

Cysteamine (Lynovex®), a novel mucoactive antimicrobial & antibiofilm agent for the treatment of cystic fibrosis

(2014) Cedric Charrier et al.   Orphanet Journal of Rare Diseases

Towards a rational combination therapy of cystic fibrosis

(2013) Valeria R. Villella et al.   Autophagy

Cysteamine: an old drug with new potential

(2013) Martine Besouw et al.   DRUG DISCOVERY TODAY

Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells

(2013) SHOTA MORIYA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Nebulized Tobramycin in the Treatment of Adult CF Pulmonary Exacerbations

(2013) Mohamed Al-Aloul et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Elevated metal concentrations in the CF airway correlate with cellular injury and disease severity

(2013) Daniel J. Smith et al.   Journal of Cystic Fibrosis

Pharmacokinetics of cysteamine bitartrate following intraduodenal delivery

(2012) Ranjan Dohil et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Incidence and Risk Factors for Pulmonary Exacerbation Treatment Failures in Patients With Cystic Fibrosis Chronically Infected With Pseudomonas aeruginosa

(2011) Michael D. Parkins et al.   CHEST

Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection

(2011) Maurizio Renna et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel respiratory symptom scoring system for CF pulmonary exacerbations

(2011) N. A. Jarad et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Failure to Recover to Baseline Pulmonary Function after Cystic Fibrosis Pulmonary Exacerbation

(2010) Don B. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Determination of the Minimal Clinically Important Difference Scores for the Cystic Fibrosis Questionnaire-Revised Respiratory Symptom Scale in Two Populations of Patients With Cystic Fibrosis and Chronic Pseudomonas aeruginosa Airway Infection

(2009) Alexandra L. Quittner et al.   CHEST

Quality of life in young people with cystic fibrosis: effects of hospitalization, age and gender, and differences in parent/child perceptions

(2009) M. Hegarty et al.   CHILD CARE HEALTH AND DEVELOPMENT

Azithromycin has an antiproliferative and autophagic effect on airway smooth muscle cells

(2009) R. Stamatiou et al.   EUROPEAN RESPIRATORY JOURNAL