Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells
Published 2013 View Full Article
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Title
Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF ONCOLOGY
Volume 42, Issue 5, Pages 1541-1550
Publisher
Spandidos Publications
Online
2013-03-28
DOI
10.3892/ijo.2013.1870
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- (2014) Daniel J. Klionsky et al. Autophagy
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- (2012) Daniel J. Klionsky et al. Autophagy
- Proteasome inhibitors in multiple myeloma: 10 years later
- (2012) P. Moreau et al. BLOOD
- Clarithromycin enhances dasatinib-induced cell death in chronic myeloid leukemia cells, by inhibition of late stage autophagy
- (2012) Lisa Schafranek et al. LEUKEMIA & LYMPHOMA
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- (2012) Angelo Michele Carella et al. LEUKEMIA & LYMPHOMA
- Blocking Autophagy Prevents Bortezomib-Induced NF-κB Activation by Reducing I-κBα Degradation in Lymphoma Cells
- (2012) Li Jia et al. PLoS One
- Guidelines for the diagnosis and management of multiple myeloma 2011
- (2011) Jennifer M. Bird et al. BRITISH JOURNAL OF HAEMATOLOGY
- Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia
- (2011) Tomasz Rzymski et al. CELL CYCLE
- Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection
- (2011) Maurizio Renna et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
- (2011) Ira Tabas et al. NATURE CELL BIOLOGY
- Autophagy as a target for anticancer therapy
- (2011) Filip Janku et al. Nature Reviews Clinical Oncology
- Ubiquitylation in ERAD: Reversing to Go Forward?
- (2011) Yien Che Tsai et al. PLOS BIOLOGY
- Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma
- (2010) Francesca Gay et al. AMERICAN JOURNAL OF HEMATOLOGY
- Multiple Myeloma
- (2010) Jacob Laubach et al. Annual Review of Medicine
- Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells
- (2010) Sudharsan Periyasamy-Thandavan et al. Autophagy
- Novel Cell- and Tissue-Based Assays for Detecting Misfolded and Aggregated Protein Accumulation Within Aggresomes and Inclusion Bodies
- (2010) Dee Shen et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
- (2010) Joo-Yong Lee et al. EMBO JOURNAL
- Proteasome Inhibitor PS-341 (Bortezomib) Induces Calpain-dependent IκBα Degradation
- (2010) Chunyang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress
- (2010) M Ri et al. LEUKEMIA
- NF-κB localization in multiple myeloma plasma cells and mesenchymal cells
- (2010) Concetta Conticello et al. LEUKEMIA RESEARCH
- Autophagy in mammalian development and differentiation
- (2010) Noboru Mizushima et al. NATURE CELL BIOLOGY
- Regulation of autophagy by ATF4 in response to severe hypoxia
- (2010) T Rzymski et al. ONCOGENE
- Bortezomib induces canonical nuclear factor- B activation in multiple myeloma cells
- (2009) T. Hideshima et al. BLOOD
- The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
- (2009) M. Milani et al. CANCER RESEARCH
- Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems
- (2009) Viktor I. Korolchuk et al. FEBS LETTERS
- A Role for Ubiquitin in Selective Autophagy
- (2009) Vladimir Kirkin et al. MOLECULAR CELL
- Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA
- (2008) S. T. Nawrocki et al. BLOOD
- Role of the Aggresome Pathway in Cancer: Targeting Histone Deacetylase 6-Dependent Protein Degradation
- (2008) A. Rodriguez-Gonzalez et al. CANCER RESEARCH
- Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways
- (2008) D. R. Fels et al. CANCER RESEARCH
- NF-??B in the pathogenesis and treatment of multiple myeloma
- (2008) Zhi-Wei Li et al. CURRENT OPINION IN HEMATOLOGY
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