Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis

E3 ubiquitin ligase TRIM7 negatively regulates NF-kappa B signaling pathway by degrading p65 in lung cancer

(2020) Jiangbo Jin et al.   CELLULAR SIGNALLING

Regorefenib induces extrinsic/intrinsic apoptosis and inhibits MAPK/NF-κB-modulated tumor progression in bladder cancer in vitro and in vivo

(2019) Chih-Hung Chiang et al.   ENVIRONMENTAL TOXICOLOGY

TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway

(2019) Xia Zhou et al.   JOURNAL OF NEURO-ONCOLOGY

Ricinus communis L. fruit extract inhibits migration/invasion, induces apoptosis in breast cancer cells and arrests tumor progression in vivo

(2019) Munmi Majumder et al.   Scientific Reports

Berbamine Enhances the Efficacy of Gefitinib by Suppressing STAT3 Signaling in Pancreatic Cancer Cells

(2019) Bingren Hu et al.   OncoTargets and Therapy

Bigelovin, a sesquiterpene lactone, suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation in liver cancer

(2018) Bei Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RIPK4 promotes bladder urothelial carcinoma cell aggressiveness by upregulating VEGF-A through the NF-κB pathway

(2018) Jian-Ye Liu et al.   BRITISH JOURNAL OF CANCER

Nuclear Factor-κB Promotes Urothelial Tumorigenesis and Cancer Progression via Cooperation with Androgen Receptor Signaling

(2018) Satoshi Inoue et al.   MOLECULAR CANCER THERAPEUTICS

Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide

(2018) Lu Lu et al.   ONCOGENE

Honokiol is a FOXM1 antagonist

(2018) Marianna Halasi et al.   Cell Death & Disease

Proscillaridin A induces apoptosis and suppresses non-small-cell lung cancer tumor growth via calcium-induced DR4 upregulation

(2018) Run-Ze Li et al.   Cell Death & Disease

Isorhamnetin suppresses PANC-1 pancreatic cancer cell proliferation through S phase arrest

(2018) Jia-Li Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CDK4/6 Inhibition in Cancer: Beyond Cell Cycle Arrest

(2018) Shom Goel et al.   TRENDS IN CELL BIOLOGY

In vitro and in vivo superior radiosensitizing effect of berbamine for head and neck squamous cell carcinoma

(2018) Hongmei Zhu et al.   OncoTargets and Therapy

ROS-modulated therapeutic approaches in cancer treatment

(2017) Muhammad Hassan Raza et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Epithelial-mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis

(2017) Tong Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

An UPLC-MS/MS method for quantifying tetrandrine and its metabolite berbamine in human blood: Application to a human pharmacokinetic study

(2017) Guangyi Yang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cell-Cycle Therapeutics Come of Age

(2017) Matthew Ingham et al.   JOURNAL OF CLINICAL ONCOLOGY

ROS in Cancer: The Burning Question

(2017) Iok In Christine Chio et al.   TRENDS IN MOLECULAR MEDICINE

Berbamine postconditioning protects the heart from ischemia/reperfusion injury through modulation of autophagy

(2017) Yanjun Zheng et al.   Cell Death & Disease

Antitumor properties of Coenzyme Q0 against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy

(2017) You-Cheng Hseu et al.   Scientific Reports

Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia

(2016) Ajay K Chaudhary et al.   Asian Pacific Journal of Cancer Prevention

4-Chlorbenzoyl Berbamine, a Novel Derivative of the Natural Product Berbamine, Potently Inhibits the Growth of Human Myeloma Cells by Modulating the NF-κB and JNK Signalling Pathways

(2016) Yun Liang et al.   CANCER INVESTIGATION

Superoxide Ion: Generation and Chemical Implications

(2016) Maan Hayyan et al.   CHEMICAL REVIEWS

Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis

(2016) Y Zhao et al.   PROSTATE CANCER AND PROSTATIC DISEASES

NF-κB in cancer therapy

(2015) Feng Li et al.   ARCHIVES OF TOXICOLOGY

Cellular Protrusions - Lamellipodia, Filopodia, Invadopodia and Podosomes - and their Roles in Progression of Orofacial Tumours: Current Understanding

(2015) Kamila Mohamed Om Alblazi et al.   Asian Pacific Journal of Cancer Prevention

Cancer treatment and survivorship statistics, 2014

(2014) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Novel Berbamine Derivative Inhibits Cell Viability and Induces Apoptosis in Cancer Stem-Like Cells of Human Glioblastoma, via Up-Regulation of miRNA-4284 and JNK/AP-1 Signaling

(2014) Fan Yang et al.   PLoS One

A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling

(2013) Fan Yang et al.   CANCER BIOLOGY & THERAPY

NF-κBP65 promotes invasion and metastasis of oesophageal squamous cell cancer by regulating matrix metalloproteinase-9 and epithelial-to-mesenchymal transition

(2013) Feng Wang et al.   CELL BIOLOGY INTERNATIONAL

Berbamine Inhibits the Growth of Liver Cancer Cells and Cancer-Initiating Cells by Targeting Ca2+/Calmodulin-Dependent Protein Kinase II

(2013) Z. Meng et al.   MOLECULAR CANCER THERAPEUTICS

Electrospray ionization mass spectrometry probing of binding affinity of berbamine, a flexible cyclic alkaloid from traditional Chinese medicine, with G-quadruplex DNA

(2013) Wei Tan et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Multiple Functions of BCL-2 Family Proteins

(2013) J. M. Hardwick et al.   Cold Spring Harbor Perspectives in Biology

Gatifloxacin Induces S and G2-Phase Cell Cycle Arrest in Pancreatic Cancer Cells via p21/p27/p53

(2012) Vikas Yadav et al.   PLoS One

Induction of apoptosis in human hepatoma SMMC-7721 cells by solamargine from Solanum nigrum L.

(2011) Xia Ding et al.   JOURNAL OF ETHNOPHARMACOLOGY

The cell cycle and cancer

(2011) Gareth H Williams et al.   JOURNAL OF PATHOLOGY

Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity

(2011) Yun Liang et al.   Journal of Zhejiang University-SCIENCE B

NF-κB suppresses ROS levels in BCR–ABL+ cells to prevent activation of JNK and cell death

(2011) S J Stein et al.   ONCOGENE

The Prognostic Significance of Apoptosis-Related Biological Markers in Chinese Gastric Cancer Patients

(2011) Xiaowen Liu et al.   PLoS One

Current therapeutic strategies for invasive and metastatic bladder cancer

(2011) Winston Tan et al.   OncoTargets and Therapy

BCL2 and CASP8 regulation by NF-κB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells

(2010) Ruchi Nehra et al.   FASEB JOURNAL

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Berbamine, a novel nuclear factor κB inhibitor, inhibits growth and induces apoptosis in human myeloma cells

(2009) Yun Liang et al.   ACTA PHARMACOLOGICA SINICA

The Antiproliferation Effect of Berbamine on K562 Resistant Cells by Inhibiting NF-κB Pathway

(2009) Yan-Lin Wei et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Role of Hydrogen Peroxide in NF-κB Activation: From Inducer to Modulator

(2009) Virgínia Oliveira-Marques et al.   ANTIOXIDANTS & REDOX SIGNALING

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-κB signaling pathways in bladder cancer cells

(2008) LiRui Zhang et al.   FEBS LETTERS