The cell cycle and cancer

BD-ProExC as Adjunct Molecular Marker for Improved Detection of CIN2+ after HPV Primary Screening

(2011) C. E. Depuydt et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

ProExC Triage of Atypical Glandular Cells on Liquid-Based Cervical Cytology Specimens

(2011) Andrew Hamilton Fletcher et al.   Journal of Lower Genital Tract Disease

Microarray-Based Class Discovery for Molecular Classification of Breast Cancer: Analysis of Interobserver Agreement

(2011) Alan Mackay et al.   JNCI-Journal of the National Cancer Institute

The Promise of a Personalized Genomic Approach to Pancreatic Cancer and Why Targeted Therapies Have Missed the Mark

(2011) William E. Fisher   WORLD JOURNAL OF SURGERY

Targeting DNA Replication before it Starts

(2010) Sara Rodriguez-Acebes et al.   AMERICAN JOURNAL OF PATHOLOGY

Eukaryotic Chromosome DNA Replication: Where, When, and How?

(2010) Hisao Masai et al.   Annual Review of Biochemistry

Diagnosis of prostate cancer by detection of minichromosome maintenance 5 protein in urine sediments

(2010) T J Dudderidge et al.   BRITISH JOURNAL OF CANCER

Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast

(2010) Seiji Matsumoto et al.   CELL CYCLE

Targeting Cell Division Cycle 7 Kinase: A New Approach for Cancer Therapy

(2010) A. Montagnoli et al.   CLINICAL CANCER RESEARCH

Molecular architecture of the DNA replication origin activation checkpoint

(2010) Slavica Tudzarova et al.   EMBO JOURNAL

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

(2010) K. Labib   GENES & DEVELOPMENT

Biomarkers in bladder cancer

(2010) Ian Proctor et al.   HISTOPATHOLOGY

Phase III Study of Enzastaurin Compared With Lomustine in the Treatment of Recurrent Intracranial Glioblastoma

(2010) Wolfgang Wick et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase III Trial of Bevacizumab Plus Interferon Alfa Versus Interferon Alfa Monotherapy in Patients With Metastatic Renal Cell Carcinoma: Final Results of CALGB 90206

(2010) Brian I. Rini et al.   JOURNAL OF CLINICAL ONCOLOGY

Ki67 in breast cancer: prognostic and predictive potential

(2010) Rinat Yerushalmi et al.   LANCET ONCOLOGY

Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy

(2010) J Rafael Sierra et al.   Molecular Cancer

The Dbf4–Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

(2010) Yi-Jun Sheu et al.   NATURE

Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer

(2009) M Loddo et al.   BRITISH JOURNAL OF CANCER

DNA Replication Licensing Factors and Aneuploidy Are Linked to Tumor Cell Cycle State and Clinical Outcome in Penile Carcinoma

(2009) O. J. Kayes et al.   CLINICAL CANCER RESEARCH

Cdc7 Kinase Is a Predictor of Survival and a Novel Therapeutic Target in Epithelial Ovarian Carcinoma

(2009) A. A. Kulkarni et al.   CLINICAL CANCER RESEARCH

Cdc7 kinase – A new target for drug development

(2009) Ronan Swords et al.   EUROPEAN JOURNAL OF CANCER

Breast Cancer Subtypes and Response to Docetaxel in Node-Positive Breast Cancer: Use of an Immunohistochemical Definition in the BCIRG 001 Trial

(2009) Judith Hugh et al.   JOURNAL OF CLINICAL ONCOLOGY

Ki67 Expression and Docetaxel Efficacy in Patients With Estrogen Receptor–Positive Breast Cancer

(2009) Frédérique Penault-Llorca et al.   JOURNAL OF CLINICAL ONCOLOGY

Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial

(2009) Paul Ellis et al.   LANCET

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Detecting High-Grade Cervical Disease on ASC-H Cytology

(2008) Momin T. Siddiqui et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in bile aspirates

(2008) L Ayaru et al.   BRITISH JOURNAL OF CANCER

ATR-dependent Activation of p38 MAP Kinase Is Responsible for Apoptotic Cell Death in Cells Depleted of Cdc7

(2008) Jun-Sub Im et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enabling personalized cancer medicine through analysis of gene-expression patterns

(2008) Laura J. van 't Veer et al.   NATURE

A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity

(2008) Alessia Montagnoli et al.   Nature Chemical Biology