Mitochondrial sorting and assembly machinery operates by β-barrel switching

Structure of a nascent membrane protein as it folds on the BAM complex

(2020) David Tomasek et al.   NATURE

Structural insight into mitochondrial β-barrel outer membrane protein biogenesis

(2020) Kathryn A. Diederichs et al.   Nature Communications

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme

(2019) Felix Boos et al.   NATURE CELL BIOLOGY

Structure of a serine-type glutathione S-transferase of Ceriporiopsis subvermispora and identification of the enzymatically important non-canonical residues by functional mutagenesis

(2019) Wan Hasnidah Wan Osman et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial protein translocation-associated degradation

(2019) Christoph U. Mårtensson et al.   NATURE

cryo_fit: Democratization of Flexible Fitting for Cryo-EM

(2019) Doo Nam Kim et al.   JOURNAL OF STRUCTURAL BIOLOGY

The big BAM theory: An open and closed case?

(2019) Runrun Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure of the mitochondrial import gate reveals distinct preprotein paths

(2019) Yuhei Araiso et al.   NATURE

Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution

(2019) Kyle Tucker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane protein insertion through a mitochondrial β-barrel gate

(2018) Alexandra I. C. Höhr et al.   SCIENCE

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

(2018) Katharina Weinhäupl et al.   CELL

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MolProbity: More and better reference data for improved all-atom structure validation

(2017) Christopher J. Williams et al.   PROTEIN SCIENCE

Template-based quaternary structure prediction of proteins using enhanced profile-profile alignments

(2017) Tsukasa Nakamura et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

The N-terminus of VDAC: Structure, mutational analysis, and a potential role in regulating barrel shape

(2016) Sabbir R. Shuvo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex

(2016) Martijn A. Huynen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10

(2016) Lars Ellenrieder et al.   Nature Communications

Characterization of the targeting signal in mitochondrial β-barrel proteins

(2016) Tobias Jores et al.   Nature Communications

Mitochondrial-bacterial hybrids of BamA/Tob55 suggest variable requirements for the membrane integration of β-barrel proteins

(2016) Anna-Katharina Pfitzner et al.   Scientific Reports

Assembly of β-barrel proteins in the mitochondrial outer membrane

(2015) Alexandra I.C. Höhr et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphatidylcholine Affects the Role of the Sorting and Assembly Machinery in the Biogenesis of Mitochondrial β-Barrel Proteins

(2015) Max-Hinderk Schuler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin

(2015) Kate E. Helmich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sam37 is crucial for formation of the mitochondrial TOM–SAM supercomplex, thereby promoting β-barrel biogenesis

(2015) Lena-Sophie Wenz et al.   JOURNAL OF CELL BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

High Resolution Structure and Double Electron-Electron Resonance of the Zebrafish Voltage-dependent Anion Channel 2 Reveal an Oligomeric Population

(2014) Johann Schredelseker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-guided simulations illuminate the mechanism of ATP transport through VDAC1

(2014) Om P Choudhary et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors

(2014) Paul A Barsanti et al.   ACS Medicinal Chemistry Letters

Coupling of Mitochondrial Import and Export Translocases by Receptor-Mediated Supercomplex Formation

(2013) Jian Qiu et al.   CELL

Role of Phosphatidylethanolamine in the Biogenesis of Mitochondrial Outer Membrane Proteins

(2013) Thomas Becker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

Conventions and workflows for usingSitus

(2012) Willy Wriggers   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Characterization of the insertase for β-barrel proteins of the outer mitochondrial membrane

(2012) Astrid Klein et al.   JOURNAL OF CELL BIOLOGY

Discovery of an archetypal protein transport system in bacterial outer membranes

(2012) Joel Selkrig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution structure of a new crystal form of BamA POTRA4–5 fromEscherichia coli

(2011) Heng Zhang et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

β-Barrel Membrane Protein Assembly by the Bam Complex

(2011) Christine L. Hagan et al.   Annual Review of Biochemistry

Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex

(2011) David A. Stroud et al.   MOLECULAR BIOLOGY OF THE CELL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mdm10 as a dynamic constituent of the TOB/SAM complex directs coordinated assembly of Tom40

(2010) Koji Yamano et al.   EMBO REPORTS

Tom7 Regulates Mdm10-mediated Assembly of the Mitochondrial Import Channel Protein Tom40

(2010) Koji Yamano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biogenesis of Mitochondria: Dual Role of Tom7 in Modulating Assembly of the Preprotein Translocase of the Outer Membrane

(2010) Thomas Becker et al.   JOURNAL OF MOLECULAR BIOLOGY

Mass Estimation of Native Proteins by Blue Native Electrophoresis

(2010) Ilka Wittig et al.   MOLECULAR & CELLULAR PROTEOMICS

Assembly of the Mitochondrial Protein Import Channel

(2010) Thomas Becker et al.   MOLECULAR BIOLOGY OF THE CELL

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Biogenesis of β-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence

(2009) Dirk M. Walther et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitochondrial Cardiolipin Involved in Outer-Membrane Protein Biogenesis: Implications for Barth Syndrome

(2009) Natalia Gebert et al.   CURRENT BIOLOGY

Biogenesis of mitochondrial outer membrane proteins

(2008) Dirk M. Walther et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

(2008) Stephan Kutik et al.   CELL

Structure of the human voltage-dependent anion channel

(2008) M. Bayrhuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Peripheral Membrane Subunits of the SAM Complex Function Codependently in Mitochondrial Outer Membrane Biogenesis

(2007) Nickie C. Chan et al.   MOLECULAR BIOLOGY OF THE CELL