Astrocyte-derived clusterin suppresses amyloid formation in vivo

Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies

(2019) Evangeline M. Foster et al.   Frontiers in Neuroscience

Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice

(2019) Sofía Fernández de Retana et al.   Alzheimers Research & Therapy

Intraventricular infusion of clusterin ameliorated cognition and pathology in Tg6799 model of Alzheimer’s disease

(2018) Xue-Mei Qi et al.   BMC NEUROSCIENCE

Associations of plasma clusterin and Alzheimer’s disease-related MRI markers in adults at mid-life: The CARDIA Brain MRI sub-study

(2018) Thaddeus Haight et al.   PLoS One

Association of the Alzheimer's Disease Clusterin Risk Allele with Plasma Clusterin Concentration

(2018) Britta Schürmann et al.   JOURNAL OF ALZHEIMERS DISEASE

Clusterin contributes to early stage of Alzheimer's disease pathogenesis

(2018) Shin-Bi Oh et al.   BRAIN PATHOLOGY

Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways

(2017) Aleksandra M. Wojtas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clusterin Binds to Aβ1–42Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation

(2016) Marten Beeg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

(2015) Casey Cook et al.   HUMAN MOLECULAR GENETICS

Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations

(2015) Karolien Bettens et al.   Molecular Neurodegeneration

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

(2013) Paramita Chakrabarty et al.   PLoS One

The Role of Clusterin in Amyloid-β–Associated Neurodegeneration

(2013) Rahul S. Desikan et al.   JAMA Neurology

Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk

(2012) Karolien Bettens et al.   Molecular Neurodegeneration

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum

(2011) Andreas Charidimou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations

(2011) Katherine Lynn Youmans et al.   JOURNAL OF NEUROSCIENCE METHODS

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

(2011) Priyanka Narayan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment

(2011) Madhav Thambisetty et al.   NEUROIMAGE

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS