Linking nutrient sensing and gene expression in Plasmodium falciparum blood‐stage parasites

Metabolic alterations in the erythrocyte during blood-stage development of the malaria parasite

(2020) Shivendra G. Tewari et al.   MALARIA JOURNAL

Modifications of histones in parasites as drug targets

(2020) Mohsin Nawaz et al.   VETERINARY PARASITOLOGY

Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites

(2020) Nanika Coetzee et al.   Scientific Reports

Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases

(2020) Krista A. Matthews et al.   ACS Infectious Diseases

Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

(2020) Aditya S. Paul et al.   Nature Communications

GCN5 acetyltransferase in cellular energetic and metabolic processes

(2020) Beste Mutlu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The antimalarial resistome – finding new drug targets and their modes of action

(2020) Krypton Carolino et al.   CURRENT OPINION IN MICROBIOLOGY

Plasmodium Para-Aminobenzoate Synthesis and Salvage Resolve Avoidance of Folate Competition and Adaptation to Host Diet

(2019) Joachim Michael Matz et al.   Cell Reports

An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases

(2019) Shi-Hui Law et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kinetic and Cross-Sectional Studies on the Genesis of Hypoargininemia in Severe Pediatric Plasmodium falciparum Malaria

(2019) Matthew P. Rubach et al.   INFECTION AND IMMUNITY

Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites

(2018) Gabrielle A. Josling et al.   Annual Review of Microbiology

Drug targets for resistant malaria: Historic to future perspectives

(2018) Sahil Kumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Parasite Sensing of Host Nutrients and Environmental Cues

(2018) Vanessa Zuzarte-Luís et al.   Cell Host & Microbe

AMPK: Sensing Glucose as well as Cellular Energy Status

(2018) Sheng-Cai Lin et al.   Cell Metabolism

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

(2018) Sharon Wein et al.   JOURNAL OF LIPID RESEARCH

Identifying the components of acidosis in patients with severe P. falciparum malaria using metabolomics

(2018) Stije J Leopold et al.   JOURNAL OF INFECTIOUS DISEASES

Evaluating antimalarial efficacy by tracking glycolysis in Plasmodium falciparum using NMR spectroscopy

(2018) Rupali Shivapurkar et al.   Scientific Reports

A Metabolomic Signature of Acute Caloric Restriction

(2017) Tinh-Hai Collet et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metabolomics-Based Elucidation of Active Metabolic Pathways in Erythrocytes and HSC-Derived Reticulocytes

(2017) Anubhav Srivastava et al.   JOURNAL OF PROTEOME RESEARCH

Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria

(2017) Judy Orikiiriza et al.   Metabolomics

A Metabolic Function for Phospholipid and Histone Methylation

(2017) Cunqi Ye et al.   MOLECULAR CELL

Nutrient sensing modulates malaria parasite virulence

(2017) Liliana Mancio-Silva et al.   NATURE

Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

(2017) Asaf Poran et al.   NATURE

Plasmodium falciparum Maf1 Confers Survival upon Amino Acid Starvation

(2017) Kyle Jarrod McLean et al.   mBio

Adaptation of Plasmodium falciparum to its transmission environment

(2017) Martin K. Rono et al.   Nature Ecology & Evolution

Host iron status and erythropoietic response to iron supplementation determines susceptibility to the RBC stage of falciparum malaria during pregnancy

(2017) Morgan M. Goheen et al.   Scientific Reports

AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions

(2016) Antero Salminen et al.   CELLULAR SIGNALLING

Nutrient sensing, signal transduction and immune responses

(2016) Jessica Walls et al.   SEMINARS IN IMMUNOLOGY

Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite

(2016) Simon A. Cobbold et al.   Scientific Reports

Anemia, Iron Supplementation and Susceptibility to Plasmodium falciparum Malaria

(2016) Ishag Adam   EBioMedicine

Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

(2016) Lucía Serrán-Aguilera et al.   Scientific Reports

What is a normal blood glucose?

(2015) Maria Güemes et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum

(2015) Sonia Gulati et al.   Cell Host & Microbe

The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite

(2015) Luciano F. Huergo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Lactate retards the development of erythrocytic stages of the human malaria parasite Plasmodium falciparum

(2015) Kenji Hikosaka et al.   PARASITOLOGY INTERNATIONAL

Host Reticulocytes Provide Metabolic Reservoirs That Can Be Exploited by Malaria Parasites

(2015) Anubhav Srivastava et al.   PLoS Pathogens

Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites

(2014) Nicolas M.B. Brancucci et al.   Cell Host & Microbe

Host Cell Phosphatidylcholine Is a Key Mediator of Malaria Parasite Survival during Liver Stage Infection

(2014) Maurice A. Itoe et al.   Cell Host & Microbe

A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion

(2014) Bradley I. Coleman et al.   Cell Host & Microbe

A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium

(2014) Abhinav Sinha et al.   NATURE

A transcriptional switch underlies commitment to sexual development in malaria parasites

(2014) Björn F. C. Kafsack et al.   NATURE

Plasmodium falciparum transmission stages accumulate in the human bone marrow

(2014) R. Joice et al.   Science Translational Medicine

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

(2014) Matthew F. Calabrese et al.   STRUCTURE

The proliferating cell hypothesis: a metabolic framework for Plasmodium growth and development

(2014) J. Enrique Salcedo-Sora et al.   TRENDS IN PARASITOLOGY

BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

(2014) Rebecca D. Oppenheim et al.   PLoS Pathogens

Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases

(2014) Pierre Crozet et al.   Frontiers in Plant Science

Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow

(2013) R. Aguilar et al.   BLOOD

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum

(2013) James I MacRae et al.   BMC BIOLOGY

Nutrient sensing and metabolic stress pathways in innate immunity

(2013) Jessica Tsalikis et al.   CELLULAR MICROBIOLOGY

Gestational Diabetes Mellitus

(2013) D. R. Coustan   CLINICAL CHEMISTRY

Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways inPlasmodium falciparum

(2013) Simon A. Cobbold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission

(2013) A. M. Bobenchik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum

(2013) Liliana Mancio-Silva et al.   Nature Communications

Fluxes in “Free” and Total Zinc Are Essential for Progression of Intraerythrocytic Stages of Plasmodium falciparum

(2012) Rebecca G. Marvin et al.   CHEMISTRY & BIOLOGY

Epigenetic Dysregulation of Virulence Gene Expression in Severe Plasmodium falciparum Malaria

(2012) Catherine J. Merrick et al.   JOURNAL OF INFECTIOUS DISEASES

Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state

(2012) S. E. Babbitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes

(2011) Ling Cai et al.   MOLECULAR CELL

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

Caloric Restriction in Humans: Impact on Physiological, Psychological, and Behavioral Outcomes

(2010) Leanne M. Redman et al.   ANTIOXIDANTS & REDOX SIGNALING

Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis

(2010) Carola Huthmacher et al.   BMC Systems Biology

Molecular Basis of RNA Polymerase III Transcription Repression by Maf1

(2010) Alessandro Vannini et al.   CELL

Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells

(2010) Boris Shor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

(2010) T. Kantidakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host-Parasite Interactions Revealed by Plasmodium falciparum Metabolomics

(2009) Kellen L. Olszewski et al.   Cell Host & Microbe

PfeIK1, a eukaryotic initiation factor 2α kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation

(2009) Clare Fennell et al.   MALARIA JOURNAL

Differential, Positional-Dependent Transcriptional Response of Antigenic Variation (var) Genes to Biological Stress in Plasmodium falciparum

(2009) Elli Rosenberg et al.   PLoS One

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

(2009) Christopher J Tonkin et al.   PLOS BIOLOGY

Histone lysine methyltransferases and demethylases in Plasmodium falciparum

(2008) Liwang Cui et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Disruption of thePlasmodium falciparum PfPMTGene Results in a Complete Loss of Phosphatidylcholine Biosynthesis via the Serine-Decarboxylase-Phosphoethanolamine-Methyltransferase Pathway and Severe Growth and Survival Defects

(2008) William Harold Witola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY