Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites
Authors
Keywords
-
Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-02-11
DOI
10.1038/s41598-020-59298-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma
- (2019) Vivian Chua et al. EMBO Molecular Medicine
- The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Plasmodium falciparum Gametocyte Development and Transmission
- (2019) Che Julius Ngwa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation
- (2019) Riëtte van Biljon et al. BMC GENOMICS
- Epigenetic Variation and Regulation in Malaria Parasites
- (2018) Manoj T. Duraisingh et al. Annual Review of Microbiology
- Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials
- (2018) Mariëtte E van der Watt et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Identification of novel quinazoline derivatives as potent antiplasmodial agents
- (2018) Anne Bouchut et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Scriptaid cause histone deacetylase inhibition and cell cycle arrest in HeLa cancer cells: A study on structural and functional aspects
- (2017) M. Janaki Ramaiah et al. GENE
- Epigenetic landscapes underlining global patterns of gene expression in the human malaria parasite, Plasmodium falciparum
- (2017) Archana P Gupta et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Histone Deacetylase Inhibitors as Anticancer Drugs
- (2017) Tomas Eckschlager et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives
- (2017) Gebremedhin S. Hailu et al. JOURNAL OF MEDICINAL CHEMISTRY
- New developments in anti-malarial target candidate and product profiles
- (2017) Jeremy N. Burrows et al. MALARIA JOURNAL
- Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity
- (2017) Sandeep Sundriyal et al. MedChemComm
- Histone 4 lysine 8 acetylation regulates proliferation and host–pathogen interaction in Plasmodium falciparum
- (2017) Archana P. Gupta et al. Epigenetics & Chromatin
- Malaria Epigenetics
- (2017) Alfred Cortés et al. Cold Spring Harbor Perspectives in Medicine
- Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum
- (2017) Che J. Ngwa et al. Frontiers in Cellular and Infection Microbiology
- Effect of clinically approved HDAC inhibitors on Plasmodium , Leishmania and Schistosoma parasite growth
- (2017) Ming Jang Chua et al. International Journal for Parasitology-Drugs and Drug Resistance
- Malaria
- (2017) Margaret A. Phillips et al. Nature Reviews Disease Primers
- Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites
- (2017) Nanika Coetzee et al. Scientific Reports
- In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species
- (2016) P. Moyo et al. JOURNAL OF ETHNOPHARMACOLOGY
- Histone Modifications and Cancer
- (2016) James E. Audia et al. Cold Spring Harbor Perspectives in Biology
- Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs
- (2016) Jesus M. Ontoria et al. ACS Medicinal Chemistry Letters
- Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite
- (2015) Giuseppe Giannini et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Why Hydroxamates May Not Be the Best Histone Deacetylase Inhibitors-What Some May Have Forgotten or Would Rather Forget?
- (2015) Sida Shen et al. ChemMedChem
- Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination
- (2015) Janette Reader et al. MALARIA JOURNAL
- A comprehensive epigenome map of Plasmodium falciparum reveals unique mechanisms of transcriptional regulation and identifies H3K36me2 as a global mark of gene suppression
- (2015) Krishanpal Karmodiya et al. Epigenetics & Chromatin
- The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells
- (2015) Y-S Lai et al. Blood Cancer Journal
- A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum
- (2015) Uchechi E. Ukaegbu et al. PLoS Genetics
- Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites
- (2015) Jessica A. Engel et al. International Journal for Parasitology-Drugs and Drug Resistance
- Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules
- (2014) Katharine Trenholme et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans
- (2014) Nicholas A. Malmquist et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Male and Female Gametocyte Functional Viability Assay To Identify Biologically Relevant Malaria Transmission-Blocking Drugs
- (2014) A. Ruecker et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Development and classes of epigenetic drugs for cancer
- (2014) Dashyant Dhanak et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea-Based HDAC Inhibitors
- (2014) Finn K. Hansen et al. ChemMedChem
- Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas
- (2014) Roberta Zappasodi et al. INTERNATIONAL JOURNAL OF CANCER
- Antitumor Effects of a Sirtuin Inhibitor, Tenovin-6, against Gastric Cancer Cells via Death Receptor 5 Up-Regulation
- (2014) Sachiko Hirai et al. PLoS One
- Epigenetic regulation of the Plasmodium falciparum genome
- (2013) M. F. Duffy et al. Briefings in Functional Genomics
- A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection
- (2013) Sarah D'Alessandro et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Malaria biology and disease pathogenesis: insights for new treatments
- (2013) Louis H Miller et al. NATURE MEDICINE
- Dynamic Epigenetic Regulation of Gene Expression during the Life Cycle of Malaria Parasite Plasmodium falciparum
- (2013) Archna P. Gupta et al. PLoS Pathogens
- Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939
- (2012) Subathdrage D. M. Sumanadasa et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells
- (2012) JING WANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells
- (2012) Junko Kikuchi et al. LUNG CANCER
- Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum
- (2012) N. A. Malmquist et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Placing the Plasmodium falciparum epigenome on the map
- (2012) Wieteke A.M. Hoeijmakers et al. TRENDS IN PARASITOLOGY
- Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide
- (2011) J Chang et al. BRITISH JOURNAL OF CANCER
- Discovery of Novel Alkylated (bis)Urea and (bis)Thiourea Polyamine Analogues with Potent Antimalarial Activities
- (2011) Bianca K. Verlinden et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ex VivoActivity of Histone Deacetylase Inhibitors against Multidrug-Resistant Clinical Isolates ofPlasmodium falciparumandP. vivax
- (2010) Jutta Marfurt et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Malaria: Could its unusual epigenome be the weak spot?
- (2010) Adriana M. Salcedo-Amaya et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2
- (2010) Barrie Peck et al. MOLECULAR CANCER THERAPEUTICS
- Histone Deacetylases Play a Major Role in the Transcriptional Regulation of the Plasmodium falciparum Life Cycle
- (2010) Balbir K. Chaal et al. PLoS Pathogens
- Targeting Histone Deacetylase Inhibitors for Anti-Malarial Therapy
- (2009) Katherine Andrews et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
- (2009) T. B. Miranda et al. MOLECULAR CANCER THERAPEUTICS
- Antimalarial Activity of Phenylthiazolyl-Bearing Hydroxamate-Based Histone Deacetylase Inhibitors
- (2008) G. S. Dow et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression during In VitroPlasmodium falciparumDevelopment
- (2008) Long Cui et al. EUKARYOTIC CELL
- Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth
- (2008) Dhaneswar Prusty et al. FEMS MICROBIOLOGY LETTERS
- Control of gene expression in Plasmodium falciparum – Ten years on
- (2008) Paul Horrocks et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now