Fucoidan Structure and Its Impact on Glucose Metabolism: Implications for Diabetes and Cancer Therapy
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Fucoidan Structure and Its Impact on Glucose Metabolism: Implications for Diabetes and Cancer Therapy
Authors
Keywords
-
Journal
Marine Drugs
Volume 19, Issue 1, Pages 30
Publisher
MDPI AG
Online
2021-01-12
DOI
10.3390/md19010030
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The anti-cancer effects of fucoidan: a review of both in vivo and in vitro investigations
- (2020) Yuan Lin et al. Cancer Cell International
- Fucoidan from Ecklonia maxima is a powerful inhibitor of the diabetes-related enzyme, α-glucosidase
- (2020) Chantal Désirée Daub et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Mechanisms of Bioactivities of Fucoidan from the Brown Seaweed Fucus vesiculosus L. of the Barents Sea
- (2020) Olga N. Pozharitskaya et al. Marine Drugs
- Structural Dependence of Sulfated Polysaccharide for Diabetes Management: Fucoidan From Undaria pinnatifida Inhibiting α-Glucosidase More Strongly Than α-Amylase and Amyloglucosidase
- (2020) Hui Si Audrey Koh et al. Frontiers in Pharmacology
- Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms
- (2019) Geert van Weelden et al. Marine Drugs
- Fucoidan from Undaria pinnatifida has anti-diabetic effects by stimulation of glucose uptake and reduction of basal lipolysis in 3 T3-L1 adipocytes
- (2019) Sung-Yi Sim et al. NUTRITION RESEARCH
- Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies
- (2019) Yu Wang et al. Marine Drugs
- GIP and GLP-1: Stepsiblings Rather Than Monozygotic Twins Within the Incretin Family
- (2019) Michael A. Nauck et al. DIABETES
- Assessing methodologies for fucoidan extraction from South African brown algae
- (2019) G.G. January et al. Algal Research-Biomass Biofuels and Bioproducts
- Low-molecular-weight fucoidan: Chemical modification, synthesis of its oligomeric fragments and mimetics
- (2019) Viktoria Evgenievna Suprunchuk CARBOHYDRATE RESEARCH
- Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy
- (2019) Ali F. Abdel-Wahab et al. PHARMACOLOGICAL RESEARCH
- Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer
- (2018) Nicholas S. Akins et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Evolution of GAPDH as a druggable target of tumor glycolysis?
- (2018) Shanmugasundaram Ganapathy-Kanniappan EXPERT OPINION ON THERAPEUTIC TARGETS
- Commercial Fucoidans from Fucus vesiculosus Can Be Grouped into Antiadipogenic and Adipogenic Agents
- (2018) Ruth Oliveira et al. Marine Drugs
- Four Key Steps Control Glycolytic Flux in Mammalian Cells
- (2018) Lukas Bahati Tanner et al. Cell Systems
- Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States
- (2018) Dongya Jia et al. Cells
- Fucoidan Extracted from Undaria pinnatifida: Source for Nutraceuticals/Functional Foods
- (2018) Yu Zhao et al. Marine Drugs
- Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis
- (2017) Zhongling Zhu et al. JOURNAL OF NEUROCHEMISTRY
- The Phytocomplex from Fucus vesiculosus and Ascophyllum nodosum Controls Postprandial Plasma Glucose Levels: An In Vitro and In Vivo Study in a Mouse Model of NASH
- (2017) Daniela Gabbia et al. Marine Drugs
- The seasonal variation of fucoidan within three species of brown macroalgae
- (2017) H.R. Fletcher et al. Algal Research-Biomass Biofuels and Bioproducts
- The Glycolytic Switch in Tumors: How Many Players Are Involved?
- (2017) Li Yu et al. Journal of Cancer
- Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
- (2016) Jay S. Skyler et al. DIABETES
- In vitro and in vivo hypoglycemic effects of brown algal fucoidans
- (2016) Xindi Shan et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling
- (2016) Sheng-Tsai Lin et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4
- (2016) Yiming Wang et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Physicochemical and Biological Characterization of Fucoidan from Fucus vesiculosus Purified by Dye Affinity Chromatography
- (2016) Ahmed Zayed et al. Marine Drugs
- Regulation of Intestinal Glucose Absorption by Ion Channels and Transporters
- (2016) Lihong Chen et al. Nutrients
- The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions
- (2016) Michael A Nauck et al. Lancet Diabetes & Endocrinology
- PFK15, a Small Molecule Inhibitor of PFKFB3, Induces Cell Cycle Arrest, Apoptosis and Inhibits Invasion in Gastric Cancer
- (2016) Wei Zhu et al. PLoS One
- Antitumor Effects of Fucoidan on Human Colon Cancer Cells via Activation of Akt Signaling
- (2015) Yong-seok Han et al. Biomolecules & Therapeutics
- Essential Role for Oxidative Phosphorylation in Cancer Progression
- (2015) Maria Chiara Maiuri et al. Cell Metabolism
- Fucoidan – A α-d-glucosidase inhibitor from Sargassum wightii with relevance to type 2 diabetes mellitus therapy
- (2015) T. Vinoth Kumar et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
- (2015) Ibtissam Marchiq et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Therapies from Fucoidan: An Update
- (2015) Janet Fitton et al. Marine Drugs
- Fucoidan Elevates MicroRNA-29b to Regulate DNMT3B-MTSS1 Axis and Inhibit EMT in Human Hepatocellular Carcinoma Cells
- (2015) Ming-De Yan et al. Marine Drugs
- Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential
- (2015) Farzaneh Atashrazm et al. Marine Drugs
- Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia
- (2015) Meng-Chuan Chen et al. Marine Drugs
- Molecular pathophysiology of hepatic glucose production
- (2015) Kfir Sharabi et al. MOLECULAR ASPECTS OF MEDICINE
- The double trouble of metabolic diseases: the diabetes–cancer link
- (2015) Slavica Tudzarova et al. MOLECULAR BIOLOGY OF THE CELL
- Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways
- (2015) YONG-SEOK HAN et al. Molecular Medicine Reports
- Bioactive compounds from brown seaweeds: Phloroglucinol, fucoxanthin and fucoidan as promising therapeutic agents against breast cancer
- (2015) D. Pádua et al. Phytochemistry Letters
- Antidiabetic potential of marine algae by inhibiting key metabolic enzymes
- (2015) P.S. Unnikrishnan et al. Frontiers in Life Science
- Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect
- (2015) Chung-Ling Lu et al. PLoS One
- The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents
- (2014) Greg M. Kowalski et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Targeting the Metabolic Plasticity of Multiple Myeloma with FDA-Approved Ritonavir and Metformin
- (2014) S. Dalva-Aydemir et al. CLINICAL CANCER RESEARCH
- Alpha-amylase and alpha-glucosidase inhibition is differentially modulated by fucoidan obtained from Fucus vesiculosus and Ascophyllum nodosum
- (2014) Kyung-Tae Kim et al. PHYTOCHEMISTRY
- The Role of SGLT1 and GLUT2 in Intestinal Glucose Transport and Sensing
- (2014) Pia V. Röder et al. PLoS One
- Fucoidan from sea cucumber protects against high-fat high-sucrose diet-induced hyperglycaemia and insulin resistance in mice
- (2014) Shiwei Hu et al. Journal of Functional Foods
- Inhibitory Potential ofTurbinaria ornataagainst Key Metabolic Enzymes Linked to Diabetes
- (2014) P. S. Unnikrishnan et al. Biomed Research International
- Safety and efficacy of acarbose in the treatment of diabetes in Chinese patients
- (2014) Xiao-Ming Mao et al. Therapeutics and Clinical Risk Management
- The inhibition of migration and invasion of cancer cells by graphene via the impairment of mitochondrial respiration
- (2013) Hejiang Zhou et al. BIOMATERIALS
- Altered energy metabolism in cancer
- (2013) Yi Zhang et al. CANCER BIOLOGY & THERAPY
- Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells
- (2013) Alexander Roesch et al. CANCER CELL
- Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer
- (2013) Cecilia Marini et al. CELL CYCLE
- AKT signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells
- (2013) Tae-Min Cho et al. FOOD AND CHEMICAL TOXICOLOGY
- Purification and structural characterization of sulfated polysaccharide from Sargassum myriocystum and its efficacy in scavenging free radicals
- (2013) V Pragasam et al. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Brown seaweed fucoidan: Biological activity and apoptosis, growth signaling mechanism in cancer
- (2013) Kalimuthu Senthilkumar et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors
- (2013) E. M. Dunbar et al. INVESTIGATIONAL NEW DRUGS
- Type 1 diabetes
- (2013) Mark A Atkinson et al. LANCET
- Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation
- (2013) Marcel Tutor Ale et al. RSC Advances
- Altered metabolism in cancer
- (2012) Jason W Locasale et al. BMC BIOLOGY
- A phase I dose-escalation trial of 2-deoxy-d-glucose alone or combined with docetaxel in patients with advanced solid tumors
- (2012) Luis E. Raez et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Role of monocarboxylate transporters in human cancers: state of the art
- (2012) Céline Pinheiro et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells
- (2012) Christophe J. De Saedeleer et al. PLoS One
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy
- (2012) Weiqin Lu et al. PLOS BIOLOGY
- Fucoidans from Brown Seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural Characteristics and Anticancer Activity
- (2011) Svetlana Ermakova et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Determination of the Na+/Glucose Cotransporter (SGLT1) Turnover Rate Using the Ion-Trap Technique
- (2011) Jean-Philippe Longpré et al. BIOPHYSICAL JOURNAL
- Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: isolation, structural characteristics, and antitumor activity
- (2011) Olesya S. Vishchuk et al. CARBOHYDRATE RESEARCH
- The monocarboxylate transporter family-Structure and functional characterization
- (2011) Andrew P. Halestrap IUBMB LIFE
- An Unfractionated Fucoidan fromAscophyllum nodosum: Extraction, Characterization, and Apoptotic Effects in Vitro
- (2011) Sarah A. Foley et al. JOURNAL OF NATURAL PRODUCTS
- Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds Inhibit Proliferation of Melanoma Cells and Induce Apoptosis by Activation of Caspase-3 in Vitro
- (2011) Marcel Tutor Ale et al. Marine Drugs
- Fucoidan from Undaria pinnatifida Induces Apoptosis in A549 Human Lung Carcinoma Cells
- (2011) Hye-Jin Boo et al. PHYTOTHERAPY RESEARCH
- Insights into digestion and absorption of major nutrients in humans
- (2010) Barbara E. Goodman ADVANCES IN PHYSIOLOGY EDUCATION
- Diabetes and Cancer: A consensus report
- (2010) E. Giovannucci et al. DIABETES CARE
- The physiological regulation of glucose flux into muscle in vivo
- (2010) D. H. Wasserman et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Inhibitory effects of fucan sulfates on enzymatic hydrolysis of starch
- (2010) MyoungLae Cho et al. LWT-FOOD SCIENCE AND TECHNOLOGY
- Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines
- (2010) Rajaa Hussien et al. PHYSIOLOGICAL GENOMICS
- Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes
- (2010) S. L. Colombo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
- (2010) A. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes
- (2009) Shrikanth H. Havale et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Fucoidan Induces Apoptosis through Activation of Caspase-8 on Human Breast Cancer MCF-7 Cells
- (2009) Yumi Yamasaki-Miyamoto et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Monthly changes in the content and monosaccharide composition of fucoidan from Undaria pinnatifida (Laminariales, Phaeophyta)
- (2009) Anna V. Skriptsova et al. JOURNAL OF APPLIED PHYCOLOGY
- 18F-FDG Avidity in Lymphoma Readdressed: A Study of 766 Patients
- (2009) M. Weiler-Sagie et al. JOURNAL OF NUCLEAR MEDICINE
- The Antitumor Effect and Hepatotoxicity of a Hexokinase II Inhibitor 3-Bromopyruvate: In Vivo Investigation of Intraarterial Administration in a Rabbit VX2 Hepatoma Model
- (2009) Hwan Jun Jae et al. KOREAN JOURNAL OF RADIOLOGY
- Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
- (2009) Olivier Feron RADIOTHERAPY AND ONCOLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Brick by brick: metabolism and tumor cell growth
- (2008) Ralph J DeBerardinis et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Fucoidan: Structure and Bioactivity
- (2008) Bo Li et al. MOLECULES
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started