The Wnt/β-Catenin Pathway is Activated as a Novel Nucleolar Stress Response

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

(2020) Peter M. Bruno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age

(2020) Rita Ferreira et al.   Cells

Dual regulation of p53 by the ribosome maturation factor SBDS

(2020) Qian Hao et al.   Cell Death & Disease

Loss of Peter Pan protein is associated with cell cycle defects and apoptotic events

(2019) Marina Keil et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

(2019) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

Emerging Role of the Nucleolar Stress Response in Autophagy

(2019) Astrid S. Pfister   Frontiers in Cellular Neuroscience

Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux

(2019) David P. Dannheisig et al.   Cells

NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes

(2019) Anaïs Darracq et al.   PLoS Genetics

Intranasal wnt-3a alleviates neuronal apoptosis in early brain injury post subarachnoid hemorrhage via the regulation of wnt target PPAN mediated by the moonlighting role of aldolase C

(2019) Wu Ruan et al.   NEUROCHEMISTRY INTERNATIONAL

Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis

(2018) Mikael S. Lindström et al.   ONCOGENE

Wnt signaling in cervical cancer?

(2018) Min Yang et al.   Journal of Cancer

Increased risk of colon cancer and osteogenic sarcoma in Diamond Blackfan anemia

(2018) Adrianna Vlachos et al.   BLOOD

Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis

(2018) Babita Madan et al.   JOURNAL OF CLINICAL INVESTIGATION

Crosstalk between NF-κB and Nucleoli in the Regulation of Cellular Homeostasis

(2018) Jingyu Chen et al.   Cells

Cancer in the National Cancer Institute inherited bone marrow failure syndrome cohort after fifteen years of follow-up

(2017) Blanche P. Alter et al.   HAEMATOLOGICA

p21: A Two-Faced Genome Guardian

(2017) Alexandros G. Georgakilas et al.   TRENDS IN MOLECULAR MEDICINE

Cancer in the National Cancer Institute inherited bone marrow failure syndrome cohort after fifteen years of follow-up

(2017) Blanche P. Alter et al.   HAEMATOLOGICA

Wnt signaling in triple-negative breast cancer

(2017) SÖ-G Pohl et al.   Oncogenesis

Tcof1-Related Molecular Networks in Treacher Collins Syndrome

(2016) Jiewen Dai et al.   JOURNAL OF CRANIOFACIAL SURGERY

β-Catenin-Independent Roles of Wnt/LRP6 Signaling

(2016) Sergio P. Acebron et al.   TRENDS IN CELL BIOLOGY

CX-5461 induces autophagy and inhibits tumor growth via mammalian target of rapamycin-related signaling pathways in osteosarcoma

(2016) Xu Li et al.   OncoTargets and Therapy

Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development

(2016) Elisa Barbieri et al.   Oncotarget

Depletion of ribosomal protein S19 causes a reduction of rRNA synthesis

(2016) Giada Juli et al.   Scientific Reports

An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in Acute Myeloid Leukemia

(2015) Erdogan Taskesen et al.   BMC BIOINFORMATICS

Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes

(2015) N. A. Zambetti et al.   HAEMATOLOGICA

The Wnt Target Protein Peter Pan Defines a Novel p53-independent Nucleolar Stress-Response Pathway

(2015) Astrid S. Pfister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells

(2015) Changbao Chen et al.   Oncotarget

Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes

(2015) N. A. Zambetti et al.   HAEMATOLOGICA

CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

(2015) Manuel Stemmer et al.   PLoS One

Mitotic Wnt Signaling Promotes Protein Stabilization and Regulates Cell Size

(2014) Sergio P. Acebron et al.   MOLECULAR CELL

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evaluating Strategies to Normalise Biological Replicates of Western Blot Data

(2014) Andrea Degasperi et al.   PLoS One

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer

(2013) Jieping Li et al.   IUBMB LIFE

High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia

(2012) K. H. Metzeler et al.   BLOOD

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

(2012) Megan J. Bywater et al.   CANCER CELL

Mitotic and mitogenic Wnt signalling

(2012) Christof Niehrs et al.   EMBO JOURNAL

Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line

(2012) Feng-Xian Qin et al.   International Journal of Medical Sciences

Amer2 Protein Interacts with EB1 Protein and Adenomatous Polyposis Coli (APC) and Controls Microtubule Stability and Cell Migration

(2012) Astrid S. Pfister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Spatial Distribution of LGR5+ Cells Correlates With Gastric Cancer Progression

(2012) Eva Simon et al.   PLoS One

p53 -Dependent and -Independent Nucleolar Stress Responses

(2012) Karl Holmberg Olausson et al.   Cells

Nucleolar stress characterized by downregulation of nucleophosmin: A novel cause of neuronal degeneration

(2011) Esther Magdalena Marquez-Lona et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pescadillo homologue 1 and Peter Pan function during Xenopus laevis pronephros development

(2011) Aleksandra Tecza et al.   BIOLOGY OF THE CELL

Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis

(2011) V. Bugner et al.   DEVELOPMENT

Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2to LRP6 phosphorylation

(2011) Kristina Tanneberger et al.   EMBO JOURNAL

Amer2 Protein Is a Novel Negative Regulator of Wnt/β-Catenin Signaling Involved in Neuroectodermal Patterning

(2011) Astrid S. Pfister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling

(2011) N. H. Kim et al.   Science Signaling

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

(2010) Denis Drygin et al.   CANCER RESEARCH

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

B23 interacts with PES1 and is involved in nucleolar localization of PES1

(2009) J. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Down-regulation of pescadillo inhibits proliferation and tumorigenicity of breast cancer cells

(2009) Jun Li et al.   CANCER SCIENCE

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity

(2009) Rachel Rau et al.   HEMATOLOGICAL ONCOLOGY

Nucleophosmin/B23 Regulates Ubiquitin Dynamics in Nucleoli by Recruiting Deubiquitylating Enzyme USP36

(2009) Akinori Endo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing

(2008) Markus Haindl et al.   EMBO REPORTS