High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia

Age-Related Prognostic Impact of Different Types ofDNMT3AMutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia

(2012) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia

(2011) A. Kuhnl et al.   BLOOD

Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

(2010) A. Gutierrez et al.   BLOOD

Rapid identification of IDH1 and IDH2 mutations in acute myeloid leukaemia using high resolution melting curve analysis

(2010) Sylvie M. Noordermeer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Prospective Evaluation of Allogeneic Hematopoietic Stem-Cell Transplantation From Matched Related and Matched Unrelated Donors in Younger Adults With High-Risk Acute Myeloid Leukemia: German-Austrian Trial AMLHD98A

(2010) Richard F. Schlenk et al.   JOURNAL OF CLINICAL ONCOLOGY

Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways

(2010) A Kohlmann et al.   LEUKEMIA

The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

(2010) Y. Wang et al.   SCIENCE

NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high-risk myelodysplastic syndrome (MDS)

(2009) F. Schneider et al.   BLOOD

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Marked downregulation of the granulopoiesis regulatorLEF1is associated with disease progression in the myelodysplastic syndromes

(2009) Andrea Pellagatti et al.   BRITISH JOURNAL OF HAEMATOLOGY

ERGExpression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis ofERG, MN1, andBAALCTranscript Levels Using Oligonucleotide Microarrays

(2009) Klaus H. Metzeler et al.   JOURNAL OF CLINICAL ONCOLOGY

An FLT3 gene-expression signature predicts clinical outcome in normal karyotype AML

(2008) L. Bullinger et al.   BLOOD

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

(2008) K. H. Metzeler et al.   BLOOD

Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome

(2008) Jinglan Xu et al.   BRITISH JOURNAL OF HAEMATOLOGY

Rapid and sensitive screening forCEBPAmutations in acute myeloid leukaemia

(2008) Tobias Benthaus et al.   BRITISH JOURNAL OF HAEMATOLOGY

Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells

(2008) Katharina Salome Minke et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

(2008) Konstantin Petropoulos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Richard F. Schlenk et al.   NEW ENGLAND JOURNAL OF MEDICINE