Mitochondrial architecture in cardiac myocytes depends on cell shape and matrix rigidity

Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction

(2020) Erzsébet Bartolák-Suki et al.   Scientific Reports

Association of mitochondria with microtubules inhibits mitochondrial fission by precluding assembly of the fission protein Dnm1

(2019) Kritika Mehta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix-guided control of mitochondrial function in cardiac myocytes

(2019) Davi M. Lyra-Leite et al.   Acta Biomaterialia

A rapid and efficient method for the isolation of postnatal murine cardiac myocyte and fibroblast cells

(2018) Jonathan J. Weldrick et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Microenvironmental Modulation of Calcium Wave Propagation Velocity in Engineered Cardiac Tissues

(2018) Andrew P. Petersen et al.   Cellular and Molecular Bioengineering

Subcellular connectomic analyses of energy networks in striated muscle

(2018) Christopher K. E. Bleck et al.   Nature Communications

Engineering micromyocardium to delineate cellular and extracellular regulation of myocardial tissue contractility

(2017) Nethika R. Ariyasinghe et al.   Integrative Biology

Regulation of Mitochondrial Structure and Dynamics by the Cytoskeleton and Mechanical Factors

(2017) Erzsébet Bartolák-Suki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Myofibrils in Cardiomyocytes Tend to Assemble Along the Maximal Principle Stress Directions

(2017) Hongyan Yuan et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Power Grid Protection of the Muscle Mitochondrial Reticulum

(2017) Brian Glancy et al.   Cell Reports

Physiological Mitochondrial Fragmentation Is a Normal Cardiac Adaptation to Increased Energy Demand

(2017) Michael Coronado et al.   CIRCULATION RESEARCH

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission

(2017) Kensuke Tsushima et al.   CIRCULATION RESEARCH

The Effect of Substrate Stiffness on Cardiomyocyte Action Potentials

(2016) Sean D. Boothe et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Hypertrophy Changes 3D Shape of hiPSC-Cardiomyocytes: Implications for Cellular Maturation in Regenerative Medicine

(2016) Cassady E. Rupert et al.   Cellular and Molecular Bioengineering

Assessing Cardiac Metabolism

(2016) Heinrich Taegtmeyer et al.   CIRCULATION RESEARCH

Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture

(2016) Alexandra I. Mot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hypertrophy induced KIF5B controls mitochondrial localization and function in neonatal rat cardiomyocytes

(2016) Wardit Tigchelaar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Physiological and pathological cardiac hypertrophy

(2016) Ippei Shimizu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial quality control: Easy come, easy go

(2015) Aleksandr Stotland et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial biogenesis and dynamics in the developing and diseased heart

(2015) Gerald W. Dorn et al.   GENES & DEVELOPMENT

Fluctuation-driven mechanotransduction regulates mitochondrial-network structure and function

(2015) Erzsébet Bartolák-Suki et al.   NATURE MATERIALS

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

(2015) Alexandre J. S. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

(2015) T. Wai et al.   SCIENCE

Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

(2015) G. Gong et al.   SCIENCE

Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle

(2015) Jaclyn P. Kerr et al.   Nature Communications

Matrix elasticity regulates the optimal cardiac myocyte shape for contractility

(2014) Megan L. McCain et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues

(2014) Megan L. McCain et al.   BIOMATERIALS

Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway

(2014) C. Pennanen et al.   JOURNAL OF CELL SCIENCE

Myocardial remodeling in hypertension

(2014) W Nadruz   JOURNAL OF HUMAN HYPERTENSION

Extracellular matrix remodeling following myocardial infarction influences the therapeutic potential of mesenchymal stem cells

(2014) Kelly Sullivan et al.   Stem Cell Research & Therapy

Heart-Specific Stiffening in Early Embryos Parallels Matrix and Myosin Expression to Optimize Beating

(2013) Stephanie Majkut et al.   CURRENT BIOLOGY

From Structure to Function: Mitochondrial Morphology, Motion and Shaping in Vascular Smooth Muscle

(2013) John G. McCarron et al.   JOURNAL OF VASCULAR RESEARCH

Myocyte Shape Regulates Lateral Registry of Sarcomeres and Contractility

(2012) Po-Ling Kuo et al.   AMERICAN JOURNAL OF PATHOLOGY

Bioenergetic role of mitochondrial fusion and fission

(2012) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondria in cardiac hypertrophy and heart failure

(2012) Mariana G. Rosca et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Reactive oxygen species contribute to the development of arrhythmogenic Ca2+waves during β-adrenergic receptor stimulation in rabbit cardiomyocytes

(2012) Elisa Bovo et al.   JOURNAL OF PHYSIOLOGY-LONDON

Development of Polydimethylsiloxane Substrates with Tunable Elastic Modulus to Study Cell Mechanobiology in Muscle and Nerve

(2012) Rachelle N. Palchesko et al.   PLoS One

Cooperative coupling of cell-matrix and cell-cell adhesions in cardiac muscle

(2012) M. L. McCain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Mitochondria–cytoskeleton interaction: Distribution of β-tubulins in cardiomyocytes and HL-1 cells

(2011) Rita Guzun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Optimization of Cardiac Metabolism in Heart Failure

(2011) Tomohisa Nagoshi et al.   CURRENT PHARMACEUTICAL DESIGN

Hierarchical architecture influences calcium dynamics in engineered cardiac muscle

(2011) Terrence Pong et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function

(2011) Megan L. McCain et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Self-Organization of Muscle Cell Structure and Function

(2011) Anna Grosberg et al.   PLoS Computational Biology

Myocyte Changes in Heart Failure

(2011) Olga V. Savinova et al.   Heart Failure Clinics

Expression of mitochondrial fusion–fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition

(2010) Sabzali Javadov et al.   BASIC RESEARCH IN CARDIOLOGY

Nuclear morphology and deformation in engineered cardiac myocytes and tissues

(2010) Mark-Anthony P. Bray et al.   BIOMATERIALS

Reactive Oxygen Species Originating From Mitochondria Regulate the Cardiac Sodium Channel

(2010) Man Liu et al.   CIRCULATION RESEARCH

Soft lithography for micro- and nanoscale patterning

(2010) Dong Qin et al.   Nature Protocols

Mitochondrial OPA1, apoptosis, and heart failure

(2009) Le Chen et al.   CARDIOVASCULAR RESEARCH

Substrate Stiffness Affects the Functional Maturation of Neonatal Rat Ventricular Myocytes

(2008) Jeffrey G. Jacot et al.   BIOPHYSICAL JOURNAL

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE

Sarcomere alignment is regulated by myocyte shape

(2008) Mark-Anthony Bray et al.   CELL MOTILITY AND THE CYTOSKELETON