The Ugly Duckling Turned to Swan: A Change in Perception of Bystander-Activated Memory CD8 T Cells

Cutting Edge: Antitumor Immunity by Pathogen-Specific CD8 T Cells in the Absence of Cognate Antigen Recognition

(2020) Derek B. Danahy et al.   JOURNAL OF IMMUNOLOGY

MHC class I-independent activation of virtual memory CD8 T cells induced by chemotherapeutic agent-treated cancer cells

(2020) Xiaoguang Wang et al.   Cellular & Molecular Immunology

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

(2019) Pamela C. Rosato et al.   Nature Communications

Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner

(2019) Isabel Barnstorf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis

(2019) Brandon L. Jutras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCR3 enables recruitment and site-specific bystander activation of memory CD8+ T cells

(2019) Nicholas J. Maurice et al.   Nature Communications

Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates

(2019) Melissa Hui Yen Chng et al.   IMMUNITY

Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

(2019) Chenghao Ge et al.   Cell Reports

Innate-like Cytotoxic Function of Bystander-Activated CD8 + T Cells Is Associated with Liver Injury in Acute Hepatitis A

(2018) Jihye Kim et al.   IMMUNITY

MAIT cells and viruses

(2018) James E Ussher et al.   IMMUNOLOGY AND CELL BIOLOGY

IL-10 Deficiency Reveals a Role for TLR2-Dependent Bystander Activation of T Cells in Lyme Arthritis

(2018) Sarah K. Whiteside et al.   JOURNAL OF IMMUNOLOGY

Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors

(2018) Thomas Duhen et al.   Nature Communications

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

(2018) Yannick Simoni et al.   NATURE

Virtual memory CD8 T cells expanded by helminth infection confer broad protection against bacterial infection

(2018) J. S. Lin et al.   Mucosal Immunology

Paracrine costimulation of IFN-γ signaling by integrins modulates CD8 T cell differentiation

(2018) Matthew F. Krummel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bystander T Cells: A Balancing Act of Friends and Foes

(2018) Sarah K. Whiteside et al.   TRENDS IN IMMUNOLOGY

Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection

(2018) Marion Rolot et al.   Nature Communications

The MAIT conundrum – how human MAIT cells distinguish bacterial colonization from infection in mucosal barrier tissues

(2017) Julia D. Berkson et al.   IMMUNOLOGY LETTERS

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses

(2017) Matthew D. Martin et al.   Frontiers in Immunology

Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis

(2016) Andrea Schietinger et al.   IMMUNITY

IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection

(2016) Souheil-Antoine Younes et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-12 Signals through the TCR To Support CD8 Innate Immune Responses

(2016) Nicholas P. Goplen et al.   JOURNAL OF IMMUNOLOGY

The Essential Role of Neutrophils during Infection with the Intracellular Bacterial PathogenListeria monocytogenes

(2016) Alexandra R. Witter et al.   JOURNAL OF IMMUNOLOGY

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation

(2016) Liyen Loh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

(2016) Jason T. White et al.   Nature Communications

Immune-surveillance through exhausted effector T-cells

(2016) Dietmar Zehn et al.   Current Opinion in Virology

IL12-mediated sensitizing of T-cell receptor-dependent and -independent tumor cell killing

(2016) Matthias Braun et al.   OncoImmunology

CXCR3 Chemokine Receptor Enables Local CD8+ T Cell Migration for the Destruction of Virus-Infected Cells

(2015) Heather D. Hickman et al.   IMMUNITY

Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+T Cells That Exacerbates Disease in Mice Coinfected withLeishmania major

(2015) Erika J. Crosby et al.   JOURNAL OF IMMUNOLOGY

Virus-specific T lymphocytes home to the skin during natural dengue infection

(2015) Laura Rivino et al.   Science Translational Medicine

Five Layers of Receptor Signaling in γδ T-Cell Differentiation and Activation

(2015) Sérgio T. Ribeiro et al.   Frontiers in Immunology

Memory-T-Cell-Derived Interferon-γ Instructs Potent Innate Cell Activation for Protective Immunity

(2014) Saïdi M’Homa Soudja et al.   IMMUNITY

IL-15: a central regulator of celiac disease immunopathology

(2014) Valérie Abadie et al.   IMMUNOLOGICAL REVIEWS

The Common  -Chain Cytokines IL-2, IL-7, IL-15, and IL-21 Induce the Expression of Programmed Death-1 and Its Ligands

(2014) A. L. Kinter et al.   JOURNAL OF IMMUNOLOGY

Distinct Requirements for Activation of NKT and NK Cells during Viral Infection

(2014) A. J. Tyznik et al.   JOURNAL OF IMMUNOLOGY

Antigen-Dependent versus -Independent Activation of Invariant NKT Cells during Infection

(2014) K. L. Holzapfel et al.   JOURNAL OF IMMUNOLOGY

Anti-Inflammatory Cytokines Directly Inhibit Innate but Not Adaptive CD8+ T Cell Functions

(2014) B. E. Freeman et al.   JOURNAL OF VIROLOGY

Bystander Activation and Anti-Tumor Effects of CD8+ T Cells Following Interleukin-2 Based Immunotherapy Is Independent of CD4+ T Cell Help

(2014) Arta M. Monjazeb et al.   PLoS One

Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection

(2014) Erika J. Crosby et al.   PLoS Pathogens

Influenza infection results in local expansion of memory CD8+T cells with antigen non-specific phenotype and function

(2013) Gail D. Sckisel et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

(2013) Talyn Chu et al.   Cell Reports

Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy

(2012) J. K. Tietze et al.   BLOOD

A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

(2012) Wolfgang Kastenmüller et al.   CELL

Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion

(2012) Saïdi M'Homa Soudja et al.   IMMUNITY

Primary Epstein-Barr virus infection does not erode preexisting CD8+T cell memory in humans

(2012) Oludare A. Odumade et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer immunoediting by the innate immune system in the absence of adaptive immunity

(2012) Timothy O’Sullivan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dissociating Markers of Senescence and Protective Ability in Memory T Cells

(2012) Martin Prlic et al.   PLoS One

Regulation of innate CD8+ T-cell activation mediated by cytokines

(2012) B. E. Freeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I Interferons Regulate Cytolytic Activity of Memory CD8+ T Cells in the Lung Airways during Respiratory Virus Challenge

(2010) Jacob E. Kohlmeier et al.   IMMUNITY

Contribution of Herpesvirus Specific CD8 T Cells to Anti-Viral T Cell Response in Humans

(2010) Elena Sandalova et al.   PLoS Pathogens

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

(2009) L. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy

(2008) Nadia Guerra et al.   IMMUNITY

Regulation of Hierarchical Clustering and Activation of Innate Immune Cells by Dendritic Cells

(2008) Suk-Jo Kang et al.   IMMUNITY