IL-10 Deficiency Reveals a Role for TLR2-Dependent Bystander Activation of T Cells in Lyme Arthritis

Two rheumatoid arthritis–specific autoantigens correlate microbial immunity with autoimmune responses in joints

(2017) Annalisa Pianta et al.   JOURNAL OF CLINICAL INVESTIGATION

Lyme Disease

(2016) Linden T. Hu   ANNALS OF INTERNAL MEDICINE

Long-term Follow-up of Patients With Lyme Disease: Longitudinal Analysis of Clinical and Quality-of-life Measures

(2016) Aprielle B. Wills et al.   CLINICAL INFECTIOUS DISEASES

Autoimmune Arthritides, Rheumatoid Arthritis, Psoriatic Arthritis, or Peripheral Spondyloarthritis Following Lyme Disease

(2016) Sheila L. Arvikar et al.   Arthritis & Rheumatology

T Cells Exacerbate Lyme Borreliosis in TLR2-Deficient Mice

(2016) Carrie E. Lasky et al.   Frontiers in Immunology

Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis

(2015) Annalisa Pianta et al.   CLINICAL IMMUNOLOGY

A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease

(2015) Jameson T. Crowley et al.   JOURNAL OF INFECTIOUS DISEASES

Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis

(2015) Robert B. Lochhead et al.   PLoS One

CD4+T Cells Promote Antibody Production but Not Sustained Affinity Maturation during Borrelia burgdorferi Infection

(2014) Rebecca A. Elsner et al.   INFECTION AND IMMUNITY

Activation of    T Cells by Borrelia burgdorferi Is Indirect via a TLR- and Caspase-Dependent Pathway

(2014) C. Collins et al.   JOURNAL OF IMMUNOLOGY

A Critical Role for Type I IFN in Arthritis Development following Borrelia burgdorferi Infection of Mice

(2014) J. C. Miller et al.   JOURNAL OF IMMUNOLOGY

Serum Inflammatory Mediators as Markers of Human Lyme Disease Activity

(2014) Mark J. Soloski et al.   PLoS One

MicroRNA-146a Provides Feedback Regulation of Lyme Arthritis but Not Carditis during Infection with Borrelia burgdorferi

(2014) Robert B. Lochhead et al.   PLoS Pathogens

The Role of Non-Cognate T Cell Stimulation during Intracellular Bacterial Infection

(2014) Stephen J. McSorley   Frontiers in Immunology

Dysregulation of CD4+CD25highT Cells in the Synovial Fluid of Patients With Antibiotic-Refractory Lyme Arthritis

(2013) Nalini K. Vudattu et al.   ARTHRITIS AND RHEUMATISM

Sustained Interactions between T Cell Receptors and Antigens Promote the Differentiation of CD4+ Memory T Cells

(2013) Chulwoo Kim et al.   IMMUNITY

A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease

(2012) Elise E. Drouin et al.   ARTHRITIS AND RHEUMATISM

Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy

(2012) Linda K. Bockenstedt et al.   JOURNAL OF CLINICAL INVESTIGATION

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

(2012) Justin D. Radolf et al.   NATURE REVIEWS MICROBIOLOGY

Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection

(2012) Monica E. Embers et al.   PLoS One

Burden and viability of Borrelia burgdorferi in skin and joints of patients with erythema migrans or lyme arthritis

(2011) Xin Li et al.   ARTHRITIS AND RHEUMATISM

Localized Production of IL-10 Suppresses Early Inflammatory Cell Infiltration and Subsequent Development of IFN- -Mediated Lyme Arthritis

(2011) F. L. Sonderegger et al.   JOURNAL OF IMMUNOLOGY

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

T regulatory cell numbers and function in patients with antibiotic-refractory or antibiotic-responsive lyme arthritis

(2010) Shiqian Shen et al.   ARTHRITIS AND RHEUMATISM

Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease

(2010) Joseph M. Reynolds et al.   IMMUNITY

T cell infiltration is associated with increased Lyme arthritis in TLR2−/−mice

(2009) Xiaohui Wang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

(2008) Minoru Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Rapid Culling of the CD4+ T Cell Repertoire in the Transition from Effector to Memory

(2008) Matthew A. Williams et al.   IMMUNITY

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

(2008) Shahla Abdollahi-Roodsaz et al.   JOURNAL OF CLINICAL INVESTIGATION