Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets

(2020) Bethan Psaila et al.   MOLECULAR CELL

SynergyFinder 2.0: visual analytics of multi-drug combination synergies

(2020) Aleksandr Ianevski et al.   NUCLEIC ACIDS RESEARCH

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing

(2019) Alba Rodriguez-Meira et al.   MOLECULAR CELL

Juvenile myelomonocytic leukemia: who’s the driver at the wheel?

(2019) Charlotte M. Niemeyer et al.   BLOOD

Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment

(2019) Aurélie Caye et al.   LEUKEMIA

Single cell analysis of normal and leukemic hematopoiesis

(2018) Benjamin J. Povinelli et al.   MOLECULAR ASPECTS OF MEDICINE

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

(2017) Alice Giustacchini et al.   NATURE MEDICINE

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis

(2017) Nathan J. Palpant et al.   Cell Reports

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality

(2016) Marios Dimitriou et al.   Oncotarget

How I treat juvenile myelomonocytic leukemia

(2015) F. Locatelli et al.   BLOOD

GPI-80 Defines Self-Renewal Ability in Hematopoietic Stem Cells during Human Development

(2015) Sacha Leandra Prashad et al.   Cell Stem Cell

Expressions of CD96 and CD123 in Bone Marrow Cells of Patients with Myelodysplastic Syndromes

(2015) Wei Zhang et al.   Clinical Laboratory

Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network

(2015) Aurélie Caye et al.   NATURE GENETICS

The genomic landscape of juvenile myelomonocytic leukemia

(2015) Elliot Stieglitz et al.   NATURE GENETICS

Expression of CD90, CD96, CD117, and CD123 on Different Hematopoietic Cell Populations from Pediatric Patients with Acute Myeloid Leukemia

(2014) Antonieta Chávez-González et al.   ARCHIVES OF MEDICAL RESEARCH

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

(2014) E. Stieglitz et al.   BLOOD

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

(2014) Petter S. Woll et al.   CANCER CELL

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Strategies for purging CD96+stem cells in vitro and in vivo

(2013) Matthias Staudinger et al.   OncoImmunology

Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty

(2012) Jeffrey A. Magee et al.   CANCER CELL

Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

(2012) M. Jan et al.   Science Translational Medicine

Hurdles Toward a Cure for CML: The CML Stem Cell

(2011) Paolo Gallipoli et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties

(2008) Christoph le Viseur et al.   CANCER CELL

Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells

(2008) L L Remsing Rix et al.   LEUKEMIA

A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death

(2008) T. E. Wood et al.   MOLECULAR CANCER THERAPEUTICS