- Home
- Publications
- Publication Search
- Publication Details
Title
Juvenile myelomonocytic leukemia: who’s the driver at the wheel?
Authors
Keywords
-
Journal
BLOOD
Volume 133, Issue 10, Pages 1060-1070
Publisher
American Society of Hematology
Online
2019-01-23
DOI
10.1182/blood-2018-11-844688
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia
- (2019) Christopher F. Krombholz et al. LEUKEMIA
- Integrated molecular profiling of juvenile myelomonocytic leukemia
- (2018) Norihiro Murakami et al. BLOOD
- Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells
- (2018) Sarah K. Tasian et al. LEUKEMIA
- Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study
- (2018) Christopher C. Dvorak et al. PEDIATRIC BLOOD & CANCER
- KMT2A-rearranged infantile acute myeloid leukemia masquerading as juvenile myelomonocytic leukemia
- (2018) Takuyo Kanayama et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Epigenetic dysregulation of the erythropoietic transcription factor KLF1 and the β-like globin locus in juvenile myelomonocytic leukemia
- (2017) Silvia Fluhr et al. Epigenetics
- De novo mutations in CBL causing early-onset paediatric moyamoya angiopathy
- (2017) Stéphanie Guey et al. JOURNAL OF MEDICAL GENETICS
- RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia
- (2017) Daniel B. Lipka et al. Nature Communications
- Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
- (2017) Elliot Stieglitz et al. Nature Communications
- Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia
- (2016) Thomas Wilhelm et al. Epigenetics
- Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2-/- c-/- mice
- (2016) C. F. Krombholz et al. HAEMATOLOGICA
- DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
- (2016) Christopher C Oakes et al. NATURE GENETICS
- Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With anNRASQ61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia
- (2016) Sunil S. Raikar et al. PEDIATRIC BLOOD & CANCER
- MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment
- (2016) Pier Paolo Leoncini et al. Oncotarget
- CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia
- (2016) Silvia Fluhr et al. Clinical Epigenetics
- Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2-/- c-/- mice
- (2016) C. F. Krombholz et al. HAEMATOLOGICA
- Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia
- (2016) Hirotoshi Sakaguchi et al. PLoS One
- Bridging to transplant with azacitidine in juvenile myelomonocytic leukemia: a retrospective analysis of the EWOG-MDS study group
- (2015) A. Cseh et al. BLOOD
- LIN28Boverexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia
- (2015) Hetty H. Helsmoortel et al. BLOOD
- JMML and RALD (Ras-associated autoimmune leukoproliferative disorder): common genetic etiology yet clinically distinct entities
- (2015) Katherine R. Calvo et al. BLOOD
- How I treat juvenile myelomonocytic leukemia
- (2015) F. Locatelli et al. BLOOD
- A novel heterozygous RIT1 mutation in a patient with Noonan syndrome, leukopenia, and transient myeloproliferation—a review of the literature
- (2015) Michaela Nemcikova et al. EUROPEAN JOURNAL OF PEDIATRICS
- Unmistakable Morphology? Infantile Malignant Osteopetrosis Resembling Juvenile Myelomonocytic Leukemia in Infants
- (2015) Anne Strauss et al. JOURNAL OF PEDIATRICS
- NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors
- (2015) K Byrgazov et al. LEUKEMIA
- Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network
- (2015) Aurélie Caye et al. NATURE GENETICS
- The genomic landscape of juvenile myelomonocytic leukemia
- (2015) Elliot Stieglitz et al. NATURE GENETICS
- Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11 -Associated Juvenile Myelomonocytic Leukemia
- (2015) Sonia Mulero-Navarro et al. Cell Reports
- Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia
- (2014) E. Stieglitz et al. BLOOD
- RASA4undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia
- (2014) Anna R Poetsch et al. Epigenetics
- Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis
- (2014) E. Flex et al. HUMAN MOLECULAR GENETICS
- Transplantation for juvenile myelomonocytic leukemia: a retrospective study of 30 children treated with a regimen of busulfan, fludarabine, and melphalan
- (2014) Miharu Yabe et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Juvenile myelomonocytic leukaemia and Noonan syndrome
- (2014) Marion Strullu et al. JOURNAL OF MEDICAL GENETICS
- Concurrent juvenile myelomonocytic leukemia and T-lymphoblastic lymphoma with a shared missense mutation inNRAS
- (2014) Brenda Ly et al. PEDIATRIC BLOOD & CANCER
- Germline Mutation ofCBLIs Associated With Moyamoya Disease in a Child With Juvenile Myelomonocytic Leukemia and Noonan Syndrome-Like Disorder
- (2014) Nobuyuki Hyakuna et al. PEDIATRIC BLOOD & CANCER
- Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia
- (2013) S. Gandre-Babbe et al. BLOOD
- Autoimmunity and persistent RAS-mutated clones long after the spontaneous regression of JMML
- (2013) M Takagi et al. LEUKEMIA
- Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia
- (2013) Hirotoshi Sakaguchi et al. NATURE GENETICS
- Validation of flow cytometric phospho-STAT5 as a diagnostic tool for juvenile myelomonocytic leukemia
- (2013) D Hasegawa et al. Blood Cancer Journal
- Autoimmune disease and multiple autoantibodies in 42 patients with RASopathies
- (2012) Caio R.D.C. Quaio et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia
- (2012) Ayami Yoshimi et al. PEDIATRIC BLOOD & CANCER
- Congenital and Childhood myeloproliferative disorders with eosinophilia responsive to imatinib
- (2012) Shirley Abraham et al. PEDIATRIC BLOOD & CANCER
- Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome
- (2011) C. Olk-Batz et al. BLOOD
- Recent advances in the pathogenesis and treatment of juvenile myelomonocytic leukaemia
- (2011) Mignon L. Loh BRITISH JOURNAL OF HAEMATOLOGY
- Non–lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatasePtpn11(Shp2) on malignant transformation of hematopoietic cells
- (2011) Dan Xu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Childhood Myelodysplastic Syndrome: Focus on the Approach to Diagnosis and Treatment of Juvenile Myelomonocytic Leukemia
- (2011) M. L. Loh Hematology-American Society of Hematology Education Program
- Autoimmune lymphoproliferative syndrome-like disease with somatic KRAS mutation
- (2010) M. Takagi et al. BLOOD
- Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis
- (2010) J. E. Niemela et al. BLOOD
- A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells
- (2010) D. Xu et al. BLOOD
- Gene Expression–Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia
- (2010) Silvia Bresolin et al. JOURNAL OF CLINICAL ONCOLOGY
- Germline mutations of the CBL gene define a new genetic syndrome with predisposition to juvenile myelomonocytic leukaemia
- (2010) B. Perez et al. JOURNAL OF MEDICAL GENETICS
- Development of T-cell Acute Lymphoblastic Leukemia in a Patient in Very Long Lasting Complete Remission of Juvenile Myelomonocytic Leukemia
- (2010) Alexei A. Maschan et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- ALK fusion genes in children with atypical myeloproliferative leukemia
- (2010) S Röttgers et al. LEUKEMIA
- Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia
- (2010) Charlotte M Niemeyer et al. NATURE GENETICS
- Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7
- (2009) I. Furlan et al. BLOOD
- Mutations in CBL occur frequently in juvenile myelomonocytic leukemia
- (2009) M. L. Loh et al. BLOOD
- Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia
- (2009) H. Muramatsu et al. BLOOD
- Germ-line mutation of theNRASgene may be responsible for the development of juvenile myelomonocytic leukaemia
- (2009) Paola De Filippi et al. BRITISH JOURNAL OF HAEMATOLOGY
- Mitotic recombination and compound-heterozygous mutations are predominant NF1-inactivating mechanisms in children with juvenile myelomonocytic leukemia and neurofibromatosis type 1
- (2009) D. Steinemann et al. HAEMATOLOGICA
- Morphologic Differential Diagnosis of Juvenile Myelomonocytic Leukemia—Pitfalls Apart From Viral Infection
- (2009) Axel Karow et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- A restricted spectrum of NRAS mutations causes Noonan syndrome
- (2009) Ion C Cirstea et al. NATURE GENETICS
- Correlation of Clinical Features With the Mutational Status of GM-CSF Signaling Pathway-Related Genes in Juvenile Myelomonocytic Leukemia
- (2009) Nao Yoshida et al. PEDIATRIC RESEARCH
- Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations
- (2008) C. Flotho et al. BLOOD
- Single-Cell Profiling Identifies Aberrant STAT5 Activation in Myeloid Malignancies with Specific Clinical and Biologic Correlates
- (2008) Nikesh Kotecha et al. CANCER CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started