Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy

Notoginsenoside R1 alleviates oxidized low-density lipoprotein-induced apoptosis, inflammatory response, and oxidative stress in HUVECS through modulation of XIST/miR-221-3p/TRAF6 axis

(2020) Jian Zhao et al.   CELLULAR SIGNALLING

Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury

(2019) Wenjun Xiong et al.   Frontiers in Physiology

Vps15 is critical to mediate autophagy in AngII treated HUVECs probably by PDK1/PKC signaling pathway

(2019) Haiyan Shan et al.   LIFE SCIENCES

Pharmacological Effects of Scutellarin, An Active Component of Genus Scutellaria and Erigeron: A Systematic Review

(2018) Sebastian Chledzik et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Mechanisms, pathophysiological roles and methods for analyzing mitophagy – recent insights

(2018) Jessica A. Williams et al.   BIOLOGICAL CHEMISTRY

Autophagy in health and disease: A comprehensive review

(2018) Sarbari Saha et al.   BIOMEDICINE & PHARMACOTHERAPY

FGF21 protects human umbilical vein endothelial cells against high glucose-induced apoptosis via PI3K/Akt/Fox3a signaling pathway

(2018) Dongmin Guo et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Scutellarin protects against vascular endothelial dysfunction and prevents atherosclerosis via antioxidation

(2018) Jiao Mo et al.   PHYTOMEDICINE

Cellular death, reactive oxygen species (ROS) and diabetic complications

(2018) Caroline Maria Oliveira Volpe et al.   Cell Death & Disease

Ethyl Rosmarinate Protects High Glucose-Induced Injury in Human Endothelial Cells

(2018) Yan-Hui Shen et al.   MOLECULES

The endothelial border to health: Mechanistic evidence of the hyperglycemic culprit of inflammatory disease acceleration

(2017) Nina Waerling Hansen et al.   IUBMB LIFE

Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle

(2017) Jun-Won Heo et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Effect of Scutellarin inhibits collagen-induced arthritis through TLR4/NF-κB-mediated inflammation

(2017) Laibo Zhang et al.   Molecular Medicine Reports

Modulating putative endothelial progenitor cells for the treatment of endothelial dysfunction and cardiovascular complications in diabetes

(2017) Julien Wils et al.   PHARMACOLOGY & THERAPEUTICS

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

(2017) Atul Kumar et al.   eLife

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

(2017) Li Xiao et al.   Redox Biology

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular docking reveals the potential of phthalate esters to inhibit the enzymes of the glucocorticoid biosynthesis pathway

(2016) Shahzad Ahmad et al.   JOURNAL OF APPLIED TOXICOLOGY

The beneficial potential of polyphenol-enriched fraction from Erigerontis Herba on metabolic syndrome

(2016) Yan Ping Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Grape seed proanthocyanidins protects against cadmium induced oxidative pancreatitis in rats by attenuating oxidative stress, inflammation and apoptosis via Nrf-2/HO-1 signaling

(2016) Nazima Bashir et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mitochondrial dynamics, mitophagy and cardiovascular disease

(2016) César Vásquez-Trincado et al.   JOURNAL OF PHYSIOLOGY-LONDON

Apigenin and naringenin ameliorate PKCβII-associated endothelial dysfunction via regulating ROS/caspase-3 and NO pathway in endothelial cells exposed to high glucose

(2016) Weiwei Qin et al.   VASCULAR PHARMACOLOGY

The research and development on the antioxidants in prevention of diabetic complications

(2016) Mohammad Rahimi-Madiseh et al.   Asian Pacific Journal of Tropical Medicine

Ameliorative effects of hispidulin on high glucose-mediated endothelial dysfunction via inhibition of PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling in endothelial cells

(2016) Weiwei Qin et al.   Journal of Functional Foods

Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular system

(2015) Yoshiyuki Ikeda et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Abnormal Glucose Metabolism in Alzheimer’s Disease: Relation to Autophagy/Mitophagy and Therapeutic Approaches

(2015) Kalpita Banerjee et al.   NEUROCHEMICAL RESEARCH

Mechanisms of the dilator action of the Erigerontis Herba on rat aorta

(2014) Chi-Man Koon et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

(2013) Teresa Fiorentino et al.   CURRENT PHARMACEUTICAL DESIGN

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

PINK1 cleavage at position A103 by the mitochondrial protease PARL

(2010) Emma Deas et al.   HUMAN MOLECULAR GENETICS

The macrophage Ox-LDL receptor, CD36 and its association with type II diabetes mellitus

(2010) Sunaina Gautam et al.   MOLECULAR GENETICS AND METABOLISM

Estrogenic and Neuroprotective Properties of Scutellarin fromErigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease

(2009) Judy Zhu et al.   PLANTA MEDICA

Scutellarin-induced endothelium-independent relaxation in rat aorta

(2008) Zhenwei Pan et al.   PHYTOTHERAPY RESEARCH

Scutellarin Isolated from Erigeron multiradiatus Inhibits High Glucose-mediated Vascular Inflammation

(2008) Pei LUO et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN