Antiresorptive-Type and Discontinuation-Timing Affect ONJ Burden

Invasive Oral Procedures and Events in Women With Postmenopausal Osteoporosis Treated With Denosumab for up to 10 Years

(2019) Nelson B Watts et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pharmacogenomics of osteonecrosis of the jaw

(2019) Guang Yang et al.   BONE

Nonsurgical Management of Medication-Related Osteonecrosis of the Jaws Using Local Wound Care

(2018) Danny Hadaya et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Development of Medication-Related Osteonecrosis of the Jaw After Extraction of Teeth With Experimental Periapical Disease

(2018) Danny Hadaya et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Vertebral Fractures After Discontinuation of Denosumab: A Post Hoc Analysis of the Randomized Placebo-Controlled FREEDOM Trial and Its Extension

(2017) Steven R Cummings et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Clinical Features of 24 Patients With Rebound-Associated Vertebral Fractures After Denosumab Discontinuation: Systematic Review and Additional Cases

(2017) Athanasios D Anastasilakis et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteonecrosis of the jaws (ONJ) in mice after extraction of teeth with periradicular disease

(2016) Akrivoula Soundia et al.   BONE

OPG-Fc but Not Zoledronic Acid Discontinuation Reverses Osteonecrosis of the Jaws (ONJ) in Mice

(2015) Rafael Scaf de Molon et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Disease Stage and Mode of Therapy Are Important Determinants of Treatment Outcomes for Medication-Related Osteonecrosis of the Jaw

(2015) Salvatore L. Ruggiero et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL

(2015) Aneta Schieferdecker et al.   Oncotarget

Spontaneous osteonecrosis of the jaws in the maxilla of mice on antiresorptive treatment: A novel ONJ mouse model

(2014) Rafael Scaf de Molon et al.   BONE

Diagnosis and Management of Osteonecrosis of the Jaw: A Systematic Review and International Consensus

(2014) Aliya A Khan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

American Association of Oral and Maxillofacial Surgeons Position Paper on Medication-Related Osteonecrosis of the Jaw—2014 Update

(2014) Salvatore L. Ruggiero et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

RANKL Inhibition Blocks Osteolytic Lesions and Reduces Skeletal Tumor Burden in Models of Non–Small-Cell Lung Cancer Bone Metastases

(2014) Robert E. Miller et al.   Journal of Thoracic Oncology

RANKL inhibition combined with tamoxifen treatment increases anti-tumor efficacy and prevents tumor-induced bone destruction in an estrogen receptor-positive breast cancer bone metastasis model

(2012) Jude Canon et al.   BREAST CANCER RESEARCH AND TREATMENT

Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid

(2012) Gabriella Misso et al.   CANCER BIOLOGY & THERAPY

Denosumab: mechanism of action and clinical outcomes

(2012) D. A. Hanley et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Adverse Effects of Bisphosphonates: Implications for Osteoporosis Management

(2012) Kurt A. Kennel et al.   MAYO CLINIC PROCEEDINGS

Bisphosphonates for Osteoporosis — Where Do We Go from Here?

(2012) Marcea Whitaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab

(2012) Athanasios Anastasilakis   Therapeutics and Clinical Risk Management

The kidney and bisphosphonates

(2011) Paul D. Miller   BONE

Periodontal disease and bisphosphonates induce osteonecrosis of the jaws in the rat

(2011) Tara L Aghaloo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Antiresorptive therapies for osteoporosis: a clinical overview

(2011) Jian Sheng Chen et al.   Nature Reviews Endocrinology

Inhibition of RANKL increases the anti-tumor effect of the EGFR inhibitor panitumumab in a murine model of bone metastasis

(2010) Jude Canon et al.   BONE

The Role of Surgical Resection in the Management of Bisphosphonate-Related Osteonecrosis of the Jaws

(2009) Eric R. Carlson et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Bisphosphonates: Mechanism of Action and Role in Clinical Practice

(2009) Matthew T. Drake et al.   MAYO CLINIC PROCEEDINGS

Phase 1 trial of denosumab safety, pharmacokinetics, and pharmacodynamics in Japanese women with breast cancer-related bone metastases

(2008) Kan Yonemori et al.   CANCER SCIENCE

RANKL Inhibition with Osteoprotegerin Increases Bone Strength by Improving Cortical and Trabecular bone Architecture in Ovariectomized Rats

(2008) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Risk of hip fracture after bisphosphonate discontinuation: implications for a drug holiday

(2008) J. R. Curtis et al.   OSTEOPOROSIS INTERNATIONAL