Zwitterion-functionalized mesoporous silica nanoparticles for enhancing oral delivery of protein drugs by overcoming multiple gastrointestinal barriers

Interactions between biomolecules and zwitterionic moieties: a review

(2020) Amir Erfani et al.   BIOMACROMOLECULES

Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions

(2020) Xiangfei Han et al.   Nature Nanotechnology

Mesoporous Silica Nanoparticles as Carriers for Therapeutic Biomolecules

(2020) Rafael R. Castillo et al.   Pharmaceutics

Mesoporous Silica Nanoparticles for Drug Delivery

(2019) Miguel Manzano et al.   ADVANCED FUNCTIONAL MATERIALS

Protective properties of mesocellular silica foams against aggregation and enzymatic hydrolysis of loaded proteins for oral protein delivery

(2019) Ye He et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Functional nanoparticles exploit the bile acid pathway to overcome multiple barriers of the intestinal epithelium for oral insulin delivery

(2018) Weiwei Fan et al.   BIOMATERIALS

Design and intestinal mucus penetration mechanism of core-shell nanocomplex

(2018) Xin Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of different cytotoxicity assays for in vitro evaluation of mesoporous silica nanoparticles

(2018) Katharina Braun et al.   TOXICOLOGY IN VITRO

Mixed-charge pseudo-zwitterionic mesoporous silica nanoparticles with low-fouling and reduced cell uptake properties

(2018) Noemí Encinas et al.   Acta Biomaterialia

Enhanced Oral Delivery of Protein Drugs Using Zwitterion-Functionalized Nanoparticles to Overcome both the Diffusion and Absorption Barriers

(2016) Wei Shan et al.   ACS Applied Materials & Interfaces

Oral delivery of diabetes peptides — Comparing standard formulations incorporating functional excipients and nanotechnologies in the translational context

(2016) Harivardhan Reddy Lakkireddy et al.   ADVANCED DRUG DELIVERY REVIEWS

Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

(2016) P. Lundquist et al.   ADVANCED DRUG DELIVERY REVIEWS

Intracellular transport of nanocarriers across the intestinal epithelium

(2016) Weiwei Fan et al.   DRUG DISCOVERY TODAY

Overcoming the Diffusion Barrier of Mucus and Absorption Barrier of Epithelium by Self-Assembled Nanoparticles for Oral Delivery of Insulin

(2015) Wei Shan et al.   ACS Nano

Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles

(2015) Irene Pereira de Sousa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Liposomes Modified with Superhydrophilic Polymer Linked to a Nonphospholipid Anchor Exhibit Reduced Complement Activation and Enhanced Circulation

(2015) Okhil K. Nag et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Multifunctional Polymer Combining the Imidazole and Zwitterion Motifs as a Biocompatible Compact Coating for Quantum Dots

(2015) Wentao Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward Oral Delivery of Biopharmaceuticals: An Assessment of the Gastrointestinal Stability of 17 Peptide Drugs

(2015) Jie Wang et al.   MOLECULAR PHARMACEUTICS

Developments of mucus penetrating nanoparticles

(2015) Min Liu et al.   Asian Journal of Pharmaceutical Sciences

Chitosan-modified porous silicon microparticles for enhanced permeability of insulin across intestinal cell monolayers

(2014) Neha Shrestha et al.   BIOMATERIALS

Zwitterionic drug nanocarriers: A biomimetic strategy for drug delivery

(2014) Qiao Jin et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles

(2013) Xiuying Li et al.   BIOMATERIALS

Mucus Penetrating Nanoparticles: Biophysical Tool and Method of Drug and Gene Delivery

(2012) Laura M. Ensign et al.   ADVANCED MATERIALS

Super-hydrophilic zwitterionic poly(carboxybetaine) and amphiphilic non-ionic poly(ethylene glycol) for stealth nanoparticles

(2012) Zhiqiang Cao et al.   Nano Today

Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers

(2011) Laura M. Ensign et al.   ADVANCED DRUG DELIVERY REVIEWS

Biodegradable Nanoparticles Composed Entirely of Safe Materials that Rapidly Penetrate Human Mucus

(2011) Ming Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of spherical mesoporous silica nanoparticles with nanometer-size controllable pores and outer diameters

(2009) Asep Bayu Dani Nandiyanto et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Effect of Surface Properties on Nanoparticle–Cell Interactions

(2009) Ayush Verma et al.   Small

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

(2008) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

The organic solute transporter  - , Ost -Ost , is essential for intestinal bile acid transport and homeostasis

(2008) A. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA