Silencing of lipocalin‐2 improves cardiomyocyte viability under iron overload conditions via decreasing mitochondrial dysfunction and apoptosis

On the physiological and cellular homeostasis of ascorbate

(2020) Magdalena Przybyło et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Keeping heart homeostasis in check through the balance of iron metabolism

(2019) Driton Vela   Acta Physiologica

Enterobactin, an iron chelating bacterial siderophore, arrests cancer cell proliferation

(2019) Piu Saha et al.   BIOCHEMICAL PHARMACOLOGY

Emerging role of mitophagy in cardiovascular physiology and pathology

(2019) Pablo E. Morales et al.   MOLECULAR ASPECTS OF MEDICINE

Holo-lipocalin-2–derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes

(2018) Erfei Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnosis and treatment of cardiac iron overload in transfusion-dependent thalassemia patients

(2018) Natthaphat Siri-Angkul et al.   Expert Review of Hematology

Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase

(2018) Bin Qi et al.   CELL

Non-transferrin-bound iron transporters

(2018) Mitchell D. Knutson   FREE RADICAL BIOLOGY AND MEDICINE

Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice

(2017) Juthamas Khamseekaew et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A combination of an iron chelator with an antioxidant exerts greater efficacy on cardioprotection than monotherapy in iron-overload thalassemic mice

(2017) Sirinart Kumfu et al.   FREE RADICAL RESEARCH

T-type and L-type Calcium Channel Blockers for the Treatment of Cardiac Iron Overload

(2017) Sirinart Kumfu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin

(2017) Fan Yang et al.   Oncotarget

Dual T-type and L-type calcium channel blocker exerts beneficial effects in attenuating cardiovascular dysfunction in iron-overloaded thalassaemic mice

(2016) Sirinart Kumfu et al.   EXPERIMENTAL PHYSIOLOGY

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

(2016) Briana R. Wilson et al.   TRENDS IN MOLECULAR MEDICINE

Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats

(2016) Suwakon Wongjaikam et al.   PLoS One

Thrombopoietin Protects Cardiomyocytes from Iron-Overload Induced Oxidative Stress and Mitochondrial Injury

(2015) Shing Chan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Iron and oxidative stress in cardiomyopathy in thalassemia

(2015) Vasilios Berdoukas et al.   FREE RADICAL BIOLOGY AND MEDICINE

The regulatory mechanisms of myogenin expression in doxorubicin-treated rat cardiomyocytes

(2015) Shu-Ting Liu et al.   Oncotarget

Plasma neutrophil gelatinase-associated lipocalin levels are markedly increased in patients with non-transfusion-dependent thalassemia: Lack of association with markers of erythropoiesis, iron metabolism and renal function

(2014) Aikaterini Patsaoura et al.   CLINICAL BIOCHEMISTRY

The Pathophysiology of Transfusional Iron Overload

(2014) John B. Porter et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Iron Overload and Apoptosis of HL-1 Cardiomyocytes: Effects of Calcium Channel Blockade

(2014) Mei-pian Chen et al.   PLoS One

Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice

(2012) Sirinart Kumfu et al.   BIOMETALS

Ferric iron uptake into cardiomyocytes of β-thalassemic mice is not through calcium channels

(2012) Sirinart Kumfu et al.   DRUG AND CHEMICAL TOXICOLOGY

T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice

(2012) Sirinart Kumfu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Inhibition of p38 MAPK During Ischemia, But Not Reperfusion, Effectively Attenuates Fatal Arrhythmia in Ischemia/Reperfusion Heart

(2012) Sirirat Surinkaew et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Chronic Cardiorenal Failure is Correlated with Endogenous Erythropoietin Levels and Decreases in Response to Low-Dose Erythropoietin Treatment

(2012) Mireille E. Emans et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Non-transferrin bound iron in Thalassemia: Differential detection of redox active forms in children and older patients

(2011) William Breuer et al.   AMERICAN JOURNAL OF HEMATOLOGY

Non-transferrin bound iron: A key role in iron overload and iron toxicity

(2011) Pierre Brissot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Iron overload thalassemic cardiomyopathy: Iron status assessment and mechanisms of mechanical and electrical disturbance due to iron toxicity

(2011) Suree Lekawanvijit et al.   CANADIAN JOURNAL OF CARDIOLOGY

Iron Overload Cardiomyopathy in Clinical Practice

(2011) Dimitrios T. Kremastinos et al.   CIRCULATION

Prognostic value of neutrophil gelatinase-associated lipocalin in acute heart failure

(2011) Margarida Alvelos et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Lipocalin-2 Induces Cardiomyocyte Apoptosis by Increasing Intracellular Iron Accumulation

(2011) Guoxiong Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron-Chelating Therapy for Transfusional Iron Overload

(2011) Gary M. Brittenham   NEW ENGLAND JOURNAL OF MEDICINE

Monitoring the efficiency of iron chelation therapy: the potential of nontransferrin-bound iron

(2010) R.C. Hider et al.   Annals of the New York Academy of Sciences

Serum ferritin: Past, present and future

(2010) Wei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Lipocalin-2/Neutrophil Gelatinase-B Associated Lipocalin Is Strongly Induced in Hearts of Rats With Autoimmune Myocarditis and in Human Myocarditis

(2010) Limin Ding et al.   CIRCULATION JOURNAL

T-type calcium channel as a portal of iron uptake into cardiomyocytes of beta-thalassemic mice

(2010) Sirinart Kumfu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Iron-Overload Cardiomyopathy: Pathophysiology, Diagnosis, and Treatment

(2010) Colm J. Murphy et al.   JOURNAL OF CARDIAC FAILURE

Iron-Induced Cardiac Damage: Role of Apoptosis and Deferasirox Intervention

(2010) Y. Wang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure

(2009) A. Yndestad et al.   EUROPEAN HEART JOURNAL

Increased Plasma Neutrophil Gelatinase-Associated Lipocalin Levels Predict Mortality in Elderly Patients with Chronic Heart Failure

(2009) Davide Bolignano et al.   REJUVENATION RESEARCH

Upregulation of Neutrophil Gelatinase-associated Lipocalin, NGAL/Lcn2, in β-Thalassemia Patients

(2008) Mehryar Habibi Roudkenar et al.   ARCHIVES OF MEDICAL RESEARCH