YAP accelerates vascular senescence via blocking autophagic flux and activating mTOR

Autophagy and senescence: A new insight in selected human diseases

(2019) Peramaiyan Rajendran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

(2019) Lina Fu et al.   PLOS BIOLOGY

Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction

(2019) Antonio Totaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular endothelial growth factor enhances tendon‐bone healing by activating Yes‐associated protein for angiogenesis induction and rotator cuff reconstruction in rats

(2019) Yao Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence

(2019) Karan Sachdeva et al.   Frontiers in Immunology

Neuregulin-1 attenuates stress-induced vascular senescence

(2018) Hadis Shakeri et al.   CARDIOVASCULAR RESEARCH

Oroxylin A inhibits ethanol-induced hepatocyte senescence via  YAP pathway

(2018) Huanhuan Jin et al.   CELL PROLIFERATION

YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6Novelty and Significance

(2018) Yang Lv et al.   CIRCULATION RESEARCH

Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis

(2018) Mariana Pavel et al.   Nature Communications

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade

(2017) Qian Zhang et al.   NATURE CELL BIOLOGY

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP

(2016) Taru Muranen et al.   CANCER RESEARCH

Polydatin post-treatment alleviates myocardial ischaemia/reperfusion injury by promoting autophagic flux

(2016) Y. Ling et al.   CLINICAL SCIENCE

Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow

(2016) Li Wang et al.   NATURE

Repression of YAP by NCTD disrupts NSCLC progression

(2016) Jiwei Guo et al.   Oncotarget

The Mediterranean Diet, its Components, and Cardiovascular Disease

(2015) R. Jay Widmer et al.   AMERICAN JOURNAL OF MEDICINE

The integration of autophagy and cellular trafficking pathways via RAB GAPs

(2015) Andreas Kern et al.   Autophagy

The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1

(2015) Carsten Gram Hansen et al.   CELL RESEARCH

Autophagy in Vascular Disease

(2015) G. R. Y. De Meyer et al.   CIRCULATION RESEARCH

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

(2015) Inge Mannaerts et al.   JOURNAL OF HEPATOLOGY

Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex

(2014) Ning Liang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

YAP/TEAD-Mediated Transcription Controls Cellular Senescence

(2013) Q. Xie et al.   CANCER RESEARCH

ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence

(2013) F Fausti et al.   CELL DEATH AND DIFFERENTIATION

Yes-associated protein homolog, YAP-1, is involved in the thermotolerance and aging in the nematode Caenorhabditis elegans

(2013) Hiroaki Iwasa et al.   EXPERIMENTAL CELL RESEARCH

Implications of autophagy for vascular smooth muscle cell function and plasticity

(2013) Joshua K. Salabei et al.   FREE RADICAL BIOLOGY AND MEDICINE

The autophagy enhancer spermidine reverses arterial aging

(2013) Thomas J. LaRocca et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Translational evidence that impaired autophagy contributes to arterial ageing

(2012) Thomas J. LaRocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hippo–YAP and mTOR pathways collaborate to regulate organ size

(2012) Alfred Csibi et al.   NATURE CELL BIOLOGY

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

Erratum: Illuminating the functional and structural repertoire of human TBC/RABGAPs

(2012) Marieke A. M. Frasa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signaling circuitries controlling stem cell fate: to be or not to be

(2011) Ramiro Iglesias-Bartolome et al.   CURRENT OPINION IN CELL BIOLOGY

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

(2011) M. Narita et al.   SCIENCE

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT