PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus

Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes

(2015) Laura Marroqui et al.   EBioMedicine

Abnormal Weight Gain and Gut Microbiota Modifications Are Side Effects of Long-Term Doxycycline and Hydroxychloroquine Treatment

(2014) Emmanouil Angelakis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Nitric Oxide Induces Ataxia Telangiectasia Mutated (ATM) Protein-dependent γH2AX Protein Formation in Pancreatic β Cells

(2014) Bryndon J. Oleson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting inflammation in the treatment of type 2 diabetes: time to start

(2014) Marc Y. Donath   NATURE REVIEWS DRUG DISCOVERY

Cyclin D3 promotes pancreatic  -cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes

(2014) N. A. Saavedra-Avila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell lines

(2014) Meriem Semache et al.   Islets

Type 2 Diabetes and Congenital Hyperinsulinism Cause DNA Double-Strand Breaks and p53 Activity in β Cells

(2013) Sharona Tornovsky-Babeay et al.   Cell Metabolism

Overexpression of Galectin-9 in Islets Prolongs Grafts Survival via Downregulation of Th1 Responses

(2013) Feng-Cheng Chou et al.   CELL TRANSPLANTATION

Induction of Diabetes in the RIP-B7.1 Mouse Model Is Critically Dependent on TLR3 and MyD88 Pathways and Is Associated With Alterations in the Intestinal Microbiome

(2013) A. K. Alkanani et al.   DIABETES

Inhibition of VEGFR-2 Reverses Type 1 Diabetes in NOD Mice by Abrogating Insulitis and Restoring Islet Function

(2013) S. Armando Villalta et al.   DIABETES

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

(2013) Miriam Cnop et al.   DIABETES

Insulin Hypersecretion in Islets From Diet-Induced Hyperinsulinemic Obese Female Mice Is Associated With Several Functional Adaptations in Individual β-Cells

(2013) Alejandro Gonzalez et al.   ENDOCRINOLOGY

Destruction of Tissue, Cells and Organelles in Type 1 Diabetic Rats Presented at Macromolecular Resolution

(2013) Raimond B. G. Ravelli et al.   Scientific Reports

Calreticulin signaling in health and disease

(2012) Wen-An Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

In Vivo Conditional Pax4 Overexpression in Mature Islet  -Cells Prevents Stress-Induced Hyperglycemia in Mice

(2011) K. H. H. He et al.   DIABETES

Hepatic Nuclear Factor 1α (HNF1α) Dysfunction Down-regulates X-box-binding Protein 1 (XBP1) and Sensitizes β-Cells to Endoplasmic Reticulum Stress

(2011) Clare L. Kirkpatrick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RasGAP-Derived Fragment N Increases the Resistance of Beta Cells towards Apoptosis in NOD Mice and Delays the Progression from Mild to Overt Diabetes

(2011) Natasa Bulat et al.   PLoS One

Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic  -Cell Death and Accelerates the Onset of Diabetes

(2010) J. Mellado-Gil et al.   DIABETES

PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression

(2009) Benoit R. Gauthier et al.   Cell Metabolism

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice

(2009) Feng-Cheng Chou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of Diminished Glucose Stimulation and Endoplasmic Reticulum Function in Nonoscillatory Pancreatic Islets

(2008) Pooya Jahanshahi et al.   ENDOCRINOLOGY