Hepatic Nuclear Factor 1α (HNF1α) Dysfunction Down-regulates X-box-binding Protein 1 (XBP1) and Sensitizes β-Cells to Endoplasmic Reticulum Stress

Dual and opposing roles of the unfolded protein response regulated by IRE1  and XBP1 in proinsulin processing and insulin secretion

(2011) A.-H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

(2010) F. Allagnat et al.   DIABETOLOGIA

Protective Unfolded Protein Response in Human Pancreatic Beta Cells Transplanted into Mice

(2010) Jeffrey Kennedy et al.   PLoS One

Detailed transcriptome atlas of the pancreatic beta cell

(2009) Burak Kutlu et al.   BMC Medical Genomics

PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression

(2009) Benoit R. Gauthier et al.   Cell Metabolism

Intersection of the unfolded protein response and hepatic lipid metabolism

(2009) Ann-Hwee Lee et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic β-cell activation

(2009) Andreas Wiederkehr et al.   EMBO JOURNAL

Mitochondrial Dysfunction Contributes to Impaired Insulin Secretion in INS-1 Cells with Dominant-negative Mutations of HNF-1α and in HNF-1α-deficient Islets

(2009) Rebecca L. Pongratz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hnf1  (MODY3) Controls Tissue-Specific Transcriptional Programs and Exerts Opposed Effects on Cell Growth in Pancreatic Islets and Liver

(2009) J.-M. Servitja et al.   MOLECULAR AND CELLULAR BIOLOGY

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATF4-Mediated Induction of 4E-BP1 Contributes to Pancreatic β Cell Survival under Endoplasmic Reticulum Stress

(2008) Suguru Yamaguchi et al.   Cell Metabolism

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum

(2008) Yusuke Adachi et al.   CELL STRUCTURE AND FUNCTION

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

(2008) Donalyn Scheuner et al.   ENDOCRINE REVIEWS

Selective Actions of Mitochondrial Fission/Fusion Genes on Metabolism-Secretion Coupling in Insulin-releasing Cells

(2008) Kyu-Sang Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using Ribosomal Protein Genes as Reference: A Tale of Caution

(2008) Lieven Thorrez et al.   PLoS One