Disturbed hypoxic responses as a pathogenic mechanism of diabetic foot ulcers

Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice

(2015) Vivekananda Gupta Sunkari et al.   WOUND REPAIR AND REGENERATION

Impaired hypoxia-inducible factor (HIF) regulation by hyperglycemia

(2014) Sergiu-Bogdan Catrina   JOURNAL OF MOLECULAR MEDICINE-JMM

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Loss of endothelial-ARNT in adult mice contributes to dampened circulating proangiogenic cells and delayed wound healing

(2014) Yu Han et al.   VASCULAR MEDICINE

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Evidence for the Use of Biological Therapies in Ulcers of the Foot in Diabetes

(2013) William J. Jeffcoate et al.   BIODRUGS

Deferoxamine enhances neovascularization and accelerates wound healing in diabetic rats via the accumulation of hypoxia-inducible factor-1α

(2013) Zhanjiang Hou et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses

(2013) Michael H. Rabinowitz   JOURNAL OF MEDICINAL CHEMISTRY

Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart

(2012) Wanli Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Impact of the Hypoxia-Inducible Factor-1   (HIF1A) Pro582Ser Polymorphism on Diabetes Nephropathy

(2012) H. F. Gu et al.   DIABETES CARE

Loss of epidermal hypoxia-inducible factor-1α accelerates epidermal aging and affects re-epithelialization in human and mouse

(2011) Hamid Reza Rezvani et al.   JOURNAL OF CELL SCIENCE

Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds

(2011) Xianjie Zhang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

(2011) Goodarz Danaei et al.   LANCET

Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure

(2011) Meredith Wetterau et al.   WOUND REPAIR AND REGENERATION

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

The Chaperone-Dependent Ubiquitin Ligase CHIP Targets HIF-1α for Degradation in the Presence of Methylglyoxal

(2010) Carla Figueira Bento et al.   PLoS One

Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1α heterozygous-null mice after burn wounding

(2010) Xianjie Zhang et al.   WOUND REPAIR AND REGENERATION

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

A hypoxic inducible factor-1α hybrid enhances collateral development and reduces vascular leakage in diabetic rats

(2009) Hidetoshi Kajiwara et al.   JOURNAL OF GENE MEDICINE

The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues

(2009) H. Thangarajah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenoviral transfer of HIF-1  enhances vascular responses to critical limb ischemia in diabetic mice

(2009) K. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

(2008) Daniel J. Ceradini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration

(2008) G. Fitsialos et al.   JOURNAL OF CELL SCIENCE

Age-dependent impairment of HIF-1α expression in diabetic mice: Correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells

(2008) Lixin Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Critical Role of HIF-1α in Keratinocyte Defense against Bacterial Infection

(2008) Carole Peyssonnaux et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Stabilization of HIF-1  is critical to improve wound healing in diabetic mice

(2008) I. R. Botusan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA