Secondary Metabolites of the Rice Blast Fungus Pyricularia oryzae: Biosynthesis and Biological Function

MoLAEA Regulates Secondary Metabolism in Magnaporthe oryzae

(2020) Pallabi Saha et al.   mSphere

Unique features of the ketosynthase domain in a non-ribosomal peptide synthetase–polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1

(2020) Choong-Soo Yun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycovirus-Induced Tenuazonic Acid Production in a Rice Blast Fungus Magnaporthe oryzae

(2020) Akihiro Ninomiya et al.   Frontiers in Microbiology

Genome Mining Reveals Neurospora crassa Can Produce the Salicylaldehyde Sordarial

(2019) Zhiyue Zhao et al.   JOURNAL OF NATURAL PRODUCTS

Development of a novel fungicide, tolprocarb

(2019) Hiroyuki Hagiwara et al.   JOURNAL OF PESTICIDE SCIENCE

Griseaketides A–D, New Aromatic Polyketides from the Pathogenic Fungus Magnaporthe grisea

(2019) Yin-He Yang et al.   MOLECULES

Tenuazonic acid from Stemphylium loti inhibits the plant plasma membrane H + ‐ATPase by a mechanism involving the C‐terminal regulatory domain

(2019) Peter K. Bjørk et al.   NEW PHYTOLOGIST

Synthesis and Absolute Configuration of Natural 2-Pyrones

(2018) Immo Burkhardt et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Induction of Nectriapyrone Biosynthesis in the Rice Blast Fungus Pyricularia oryzae by Disturbance of the Two-Component Signal Transduction System

(2018) Takayuki Motoyama et al.   CHEMBIOCHEM

Synthesis and activities of tolprocarb derivatives against Pyricularia oryzae: relationships among the activities for polyketide synthase, melanin biosynthesis, and rice blast

(2017) Shinichi Banba et al.   JOURNAL OF PESTICIDE SCIENCE

Increased metabolite production by deletion of an HDA1-type histone deacetylase in the phytopathogenic fungi, Magnaporthe oryzae (Pyricularia oryzae ) and Fusarium asiaticum

(2017) K. Maeda et al.   LETTERS IN APPLIED MICROBIOLOGY

Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae

(2017) Stefan Jacob et al.   MICROBIOLOGY-SGM

Recent advances in tenuazonic acid as a potential herbicide

(2017) Shiguo Chen et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Regulation and Role of Fungal Secondary Metabolites

(2016) Juliane Macheleidt et al.   Annual Review of Genetics

Biosynthesis of α-pyrones

(2016) Till F Schäberle   Beilstein Journal of Organic Chemistry

Biosynthetic approaches to creating bioactive fungal metabolites: Pathway engineering and activation of secondary metabolism

(2016) Takayuki Motoyama et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Gibepyrone Biosynthesis in the Rice PathogenFusarium fujikuroiIs Facilitated by a Small Polyketide Synthase Gene Cluster

(2016) Slavica Janevska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quinone/hydroquinone meroterpenoids with antitubercular and cytotoxic activities produced by the sponge-derived fungus Gliomastix sp. ZSDS1-F7

(2016) Wei-Jun He et al.   NATURAL PRODUCT RESEARCH

A new α-pyrone from the mangrove endophytic fungus Phomopsis sp. HNY29-2B

(2016) Runlin Cai et al.   NATURAL PRODUCT RESEARCH

Cytokinin Production by the Rice Blast Fungus Is a Pivotal Requirement for Full Virulence

(2016) Emilie Chanclud et al.   PLoS Pathogens

Two new monoterpenoid α-pyrones from a fungusNectriasp. HLS206 associated with the marine spongeGelliodes carnosa

(2015) Ting Gong et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Gulypyrones A and B and Phomentrioloxins B and C Produced by Diaporthe gulyae, a Potential Mycoherbicide for Saffron Thistle (Carthamus lanatus)

(2015) Anna Andolfi et al.   JOURNAL OF NATURAL PRODUCTS

Uncovering the structures of modular polyketide synthases

(2015) Kira J. Weissman   NATURAL PRODUCT REPORTS

A fungal monooxygenase-derived jasmonate attenuates host innate immunity

(2015) Rajesh N Patkar et al.   Nature Chemical Biology

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

(2015) Peter J. Rutledge et al.   NATURE REVIEWS MICROBIOLOGY

Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae

(2015) Zhongshu Song et al.   Chemical Science

Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

(2015) Choong-Soo Yun et al.   Nature Communications

Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters

(2015) Tina Netzker et al.   Frontiers in Microbiology

Crucial Roles of Abscisic Acid Biogenesis in Virulence of Rice Blast Fungus Magnaporthe oryzae

(2015) Carla A. Spence et al.   Frontiers in Plant Science

Paenilamicin: Structure and Biosynthesis of a Hybrid Nonribosomal Peptide/Polyketide Antibiotic from the Bee PathogenPaenibacillus larvae

(2014) Sebastian Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cis-Double Bond Formation by Thioesterase and Transfer by Ketosynthase in FR901464 Biosynthesis

(2014) Hai-Yan He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fungal type III polyketide synthases

(2014) Makoto Hashimoto et al.   NATURAL PRODUCT REPORTS

Structure of a modular polyketide synthase

(2014) Somnath Dutta et al.   NATURE

Blocking the QB-binding site of photosystem II by tenuazonic acid, a non-host-specific toxin ofAlternaria alternata, activates singlet oxygen-mediated and EXECUTER-dependent signalling inArabidopsis

(2014) SHIGUO CHEN et al.   PLANT CELL AND ENVIRONMENT

Polyketides from the mangrove-derived endophytic fungus Acremonium strictum

(2014) Lena Hammerschmidt et al.   TETRAHEDRON LETTERS

Potential health hazards due to the occurrence of the mycotoxin tenuazonic acid in infant food

(2013) Stefan Asam et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Vinylogous chain branching catalysed by a dedicated polyketide synthase module

(2013) Tom Bretschneider et al.   NATURE

Pyrones as bacterial signaling molecules

(2013) Alexander O Brachmann et al.   Nature Chemical Biology

Hypocreaterpenes A and B, cadinane-type sesquiterpenes from a marine-derived fungus, Hypocreales sp.

(2013) Hong Zhu et al.   Phytochemistry Letters

Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS

(2013) Katja Maria Fisch   RSC Advances

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

(2012) Kozo Ochi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular Diversity Sculpted by Fungal PKS-NRPS Hybrids

(2012) Daniela Boettger et al.   CHEMBIOCHEM

Characterization of a Fungal Thioesterase Having Claisen Cyclase and Deacetylase Activities in Melanin Biosynthesis

(2012) Anna L. Vagstad et al.   CHEMISTRY & BIOLOGY

Large-Scale Synthesis of Isotopically Labeled 13C2-Tenuazonic Acid and Development of a Rapid HPLC-MS/MS Method for the Analysis of Tenuazonic Acid in Tomato and Pepper Products

(2012) Lilia Lohrey et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cytokinins Act Synergistically with Salicylic Acid to Activate Defense Gene Expression in Rice

(2012) Chang-Jie Jiang et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain

(2012) Xue Gao et al.   Nature Chemical Biology

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

The Insect Pathogen Serratia marcescens Db10 Uses a Hybrid Non-Ribosomal Peptide Synthetase-Polyketide Synthase to Produce the Antibiotic Althiomycin

(2012) Amy J. Gerc et al.   PLoS One

A Branched Extender Unit Shared between Two Orthogonal Polyketide Pathways in an Endophyte

(2011) Zhongli Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Biotransformation of Plausible Biosynthetic Intermediates of Salicylaldehyde-Type Phytotoxins of Rice Blast Fungus, Magnaporthe grisea

(2011) Koji Tanaka et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Phytotoxic polyketides produced by Phomopsis foeniculi, a strain isolated from diseased Bulgarian fennel

(2011) Antonio Evidente et al.   EUROPEAN JOURNAL OF PLANT PATHOLOGY

Enzyme Immunoassay for Tenuazonic Acid in Apple and Tomato Products

(2011) Madeleine Gross et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Physiological role of germicidins in spore germination and hyphal elongation in Streptomyces coelicolor A3(2)

(2011) Yuu Aoki et al.   JOURNAL OF ANTIBIOTICS

Transcriptional regulatory elements in fungal secondary metabolism

(2011) Wenbing Yin et al.   JOURNAL OF MICROBIOLOGY

Auxin Production by the Rice Blast Fungus and its Localization in Host Tissue

(2011) Eiji Tanaka et al.   JOURNAL OF PHYTOPATHOLOGY

Abscisic Acid Interacts Antagonistically with Salicylic Acid Signaling Pathway in Rice–Magnaporthe griseaInteraction

(2010) Chang-Jie Jiang et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria

(2010) J. A. V. Blodgett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chloroplastic oxidative burst induced by tenuazonic acid, a natural photosynthesis inhibitor, triggers cell necrosis in Eupatorium adenophorum Spreng

(2009) Shiguo Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Biological activities from extracts of endophytic fungi isolated fromViguiera arenariaandTithonia diversifolia

(2009) Denise O. Guimarães et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Three new compounds from endophytic fungus L10 ofCephalotaxus hainanensis

(2009) Xuan Lu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Determination of the Alternaria mycotoxin tenuazonic acid in cereals by high-performance liquid chromatography–electrospray ionization ion-trap multistage mass spectrometry after derivatization with 2,4-dinitrophenylhydrazine

(2009) David Siegel et al.   JOURNAL OF CHROMATOGRAPHY A

Magnaporthe griseaavirulence geneACE1belongs to an infection-specific gene cluster involved in secondary metabolism

(2008) Jérôme Collemare et al.   NEW PHYTOLOGIST

Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase

(2008) A. Tanovic et al.   SCIENCE

VelB/VeA/LaeA Complex Coordinates Light Signal with Fungal Development and Secondary Metabolism

(2008) O. Bayram et al.   SCIENCE

Alternaria mycotoxins: an overview of chemical characterization, producers, toxicity, analysis and occurrence in foodstuffs

(2008) V. Ostry   World Mycotoxin Journal

Biosynthesis of secondary metabolites in the rice blast fungus Magnaporthe grisea: the role of hybrid PKS-NRPS in pathogenicity

(2007) Jérôme Collemare et al.