Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

The Alternaria genomes database: a comprehensive resource for a fungal genus comprised of saprophytes, plant pathogens, and allergenic species

(2015) Ha X Dang et al.   BMC GENOMICS

Structural Basis for the Formation of Acylalkylpyrones from Two β-Ketoacyl Units by the Fungal Type III Polyketide Synthase CsyB

(2015) Takahiro Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paenilamicin: Structure and Biosynthesis of a Hybrid Nonribosomal Peptide/Polyketide Antibiotic from the Bee PathogenPaenibacillus larvae

(2014) Sebastian Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reconstructing fungal natural product biosynthetic pathways

(2014) C. M. Lazarus et al.   NATURAL PRODUCT REPORTS

Fungal type III polyketide synthases

(2014) Makoto Hashimoto et al.   NATURAL PRODUCT REPORTS

One pathway, many compounds: heterologous expression of a fungal biosynthetic pathway reveals its intrinsic potential for diversity

(2013) Zahida Wasil et al.   Chemical Science

Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS

(2013) Katja Maria Fisch   RSC Advances

Phylogenetic Study of Polyketide Synthases and Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Mycotoxins

(2013) Antonia Gallo et al.   Toxins

Molecular Diversity Sculpted by Fungal PKS-NRPS Hybrids

(2012) Daniela Boettger et al.   CHEMBIOCHEM

Quartromicin Biosynthesis: Two Alternative Polyketide Chains Produced by One Polyketide Synthase Assembly Line

(2012) Hai-Yan He et al.   CHEMISTRY & BIOLOGY

Large-Scale Synthesis of Isotopically Labeled 13C2-Tenuazonic Acid and Development of a Rapid HPLC-MS/MS Method for the Analysis of Tenuazonic Acid in Tomato and Pepper Products

(2012) Lilia Lohrey et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

(2012) Yit-Heng Chooi et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain

(2012) Xue Gao et al.   Nature Chemical Biology

The Insect Pathogen Serratia marcescens Db10 Uses a Hybrid Non-Ribosomal Peptide Synthetase-Polyketide Synthase to Produce the Antibiotic Althiomycin

(2012) Amy J. Gerc et al.   PLoS One

Enzyme Immunoassay for Tenuazonic Acid in Apple and Tomato Products

(2011) Madeleine Gross et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

An in vitro system to study cyclopeptide heterophyllin B biosynthesis in the medicinal plant Pseudostellaria heterophylla

(2011) Wenyan Xu et al.   PLANT CELL TISSUE AND ORGAN CULTURE

In vitro reconstruction of tetronate RK-682 biosynthesis

(2010) Yuhui Sun et al.   Nature Chemical Biology

Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria

(2010) J. A. V. Blodgett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis

(2010) T. P. Korman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization ofcyclo-Acetoacetyl-l-Tryptophan Dimethylallyltransferase in Cyclopiazonic Acid Biosynthesis: Substrate Promiscuity and Site Directed Mutagenesis Studies

(2009) Xinyu Liu et al.   BIOCHEMISTRY

Determination of the Alternaria mycotoxin tenuazonic acid in cereals by high-performance liquid chromatography–electrospray ionization ion-trap multistage mass spectrometry after derivatization with 2,4-dinitrophenylhydrazine

(2009) David Siegel et al.   JOURNAL OF CHROMATOGRAPHY A

A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, inAspergillus nidulans

(2009) Yi-Ming Chiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chromatin-level regulation of biosynthetic gene clusters

(2009) Jin Woo Bok et al.   Nature Chemical Biology

Hidden biosynthetic treasures brought to light

(2009) Christian Hertweck   Nature Chemical Biology

Authentic Heterologous Expression of the Tenellin Iterative Polyketide Synthase Nonribosomal Peptide Synthetase Requires Coexpression with an Enoyl Reductase

(2008) Laura M. Halo et al.   CHEMBIOCHEM

Thioesterase-Like Role for Fungal PKS-NRPS Hybrid Reductive Domains

(2008) James W. Sims et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alternaria mycotoxins: an overview of chemical characterization, producers, toxicity, analysis and occurrence in foodstuffs

(2008) V. Ostry   World Mycotoxin Journal

Biosynthesis of secondary metabolites in the rice blast fungus Magnaporthe grisea: the role of hybrid PKS-NRPS in pathogenicity

(2007) Jérôme Collemare et al.