Potential Role of Insulin Growth-Factor-Binding Protein 2 as Therapeutic Target for Obesity-Related Insulin Resistance
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Potential Role of Insulin Growth-Factor-Binding Protein 2 as Therapeutic Target for Obesity-Related Insulin Resistance
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 3, Pages 1133
Publisher
MDPI AG
Online
2021-01-25
DOI
10.3390/ijms22031133
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Proteome-wide assessment of diabetes mellitus in Qatari identifies IGFBP-2 as a risk factor already with early glycaemic disturbances
- (2020) Raymond Noordam et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Effects of gastric sleeve surgery on the serum levels of GH, IGF-1 and IGF-binding protein 2 in healthy obese patients
- (2020) Khalid Al-Regaiey et al. BMC GASTROENTEROLOGY
- Analyses of IGFBP2 DNA methylation and mRNA expression in visceral and subcutaneous adipose tissues of obese subjects
- (2019) Xiuli Zhang et al. GROWTH HORMONE & IGF RESEARCH
- Insulin-Like Growth Factor Axis Biomarkers and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
- (2019) Xi-Rui Wang et al. Frontiers in Endocrinology
- Transcriptional Analysis of FOXO1, C/EBP- and PPAR-2 Genes and Their association with Obesity-Related Insulin Resistance
- (2019) Boughanem et al. Genes
- Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis
- (2018) Isuru R. Kumarasinghe et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?
- (2018) John B. Allard et al. Frontiers in Endocrinology
- SIRT6 haploinsufficiency induces BRAFV600E melanoma cell resistance to MAPK inhibitors via IGF signalling
- (2018) Thomas Strub et al. Nature Communications
- Proteins Altered by Surgical Weight Loss Highlight Biomarkers of Insulin Resistance in the Community
- (2018) Ravi V. Shah et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes
- (2018) Clemens Wittenbecher et al. DIABETES
- Ensembl 2019
- (2018) Fiona Cunningham et al. NUCLEIC ACIDS RESEARCH
- Sex-specific correlation of IGFBP-2 and IGFBP-3 with vitamin D status in adults with obesity: a cross-sectional serum proteomics study
- (2018) Nasser M. Al-Daghri et al. Nutrition & Diabetes
- IGFBP-2 and aging: a 20-year longitudinal study on IGFBP-2, IGF-I, BMI, insulin sensitivity and mortality in an aging population
- (2018) Annewieke W van den Beld et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Changes in IGFBP-2 levels following a one-year lifestyle modification program are independently related to improvements in plasma apo B and LDL apo B levels
- (2018) Sophie Carter et al. ATHEROSCLEROSIS
- Differential basal and exercise-induced IGF-I system responses to resistance vs. calisthenic-based military readiness training programs
- (2017) Bradley C. Nindl et al. GROWTH HORMONE & IGF RESEARCH
- IGFBP-3 Interacts with the Vitamin D Receptor in Insulin Signaling Associated with Obesity in Visceral Adipose Tissue
- (2017) Inmaculada Moreno-Santos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Relationships of insulin-like growth factor-1, its binding proteins, and cardiometabolic risk in hypertensive perimenopausal women
- (2017) Agnieszka Olszanecka et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes
- (2017) Biruhalem Assefa et al. Oxidative Medicine and Cellular Longevity
- The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA
- (2017) Chin-Cheng Lee et al. PLoS One
- Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort
- (2016) Yeyi Zhu et al. DIABETES
- Postpartum IGF-I and IGFBP-2 levels are prospectively associated with the development of type 2 diabetes in women with previous gestational diabetes mellitus
- (2016) M. Lappas et al. DIABETES & METABOLISM
- Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies
- (2016) Lynette M Phillips et al. JOURNAL OF PATHOLOGY
- Insulin-like growth factor binding protein-2 regulates β-catenin signaling pathway in glioma cells and together contributes to poor patient prognosis
- (2016) Shilpa S. Patil et al. NEURO-ONCOLOGY
- IGFBP-2 and -3 co-ordinately regulate IGF1 induced matrix mineralisation of differentiating human dental pulp cells
- (2016) Hanaa Alkharobi et al. Stem Cell Research
- Insulin-like growth factor axis in pregnancies affected by fetal growth disorders
- (2016) Aamod R. Nawathe et al. Clinical Epigenetics
- ITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cells
- (2016) E. M. Morandi et al. Scientific Reports
- Relevance of fruits, vegetables and flavonoids from fruits and vegetables during early life, mid-childhood and adolescence for levels of insulin-like growth factor (IGF-1) and its binding proteins IGFBP-2 and IGFBP-3 in young adulthood
- (2015) Danika Krupp et al. BRITISH JOURNAL OF NUTRITION
- Phosphatidylinositol 3-kinase (PI3K) signalling regulates insulin-like-growth factor binding protein-2 (IGFBP-2) production in human adipocytes
- (2015) Franziska Wilhelm et al. GROWTH HORMONE & IGF RESEARCH
- HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures
- (2015) Adam Pickard et al. PLoS Pathogens
- Circulating IGFBP-2 levels are incrementally linked to correlates of the metabolic syndrome and independently associated with VLDL triglycerides
- (2014) Sophie Carter et al. ATHEROSCLEROSIS
- IGFBP2 Is Neither Sufficient nor Necessary for the Physiological Actions of Leptin on Glucose Homeostasis in Maleob/obMice
- (2014) Ursula H. Neumann et al. ENDOCRINOLOGY
- Leptin Enhances Insulin Sensitivity by Direct and Sympathetic Nervous System Regulation of Muscle IGFBP-2 Expression: Evidence From Nonrodent Models
- (2014) Steven W. Yau et al. ENDOCRINOLOGY
- IGFBP-2 Directly Stimulates Osteoblast Differentiation
- (2014) Gang Xi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Heparin-binding mechanism of the IGF2/IGF-binding protein 2 complex
- (2014) Jacob Lund et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Rutin potentiates calcium uptake via voltage-dependent calcium channel associated with stimulation of glucose uptake in skeletal muscle
- (2013) Virginia Demarchi Kappel et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery
- (2013) Markus Ahrens et al. Cell Metabolism
- Hyperglycaemia-induced chemoresistance of prostate cancer cells due to IGFBP2
- (2013) K M Biernacka et al. ENDOCRINE-RELATED CANCER
- The Heparin-Binding Domains of IGFBP-2 Mediate Its Inhibitory Effect on Preadipocyte Differentiation and Fat Development in Male Mice
- (2013) Gang Xi et al. ENDOCRINOLOGY
- Why cellular stress suppresses adipogenesis in skeletal tissue, but is ineffective in adipose tissue: Control of mesenchymal cell differentiation via integrin binding sites in extracellular matrices
- (2013) Vladimir Volloch et al. MATRIX BIOLOGY
- Exercise-Induced Insulin-Like Growth Factor I System Concentrations after Training in Women
- (2013) SARA M. GREGORY et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells
- (2013) W J Azar et al. ONCOGENE
- A cross-sectional analysis of the association between diet and insulin-like growth factor (IGF)-I, IGF-II, IGF-binding protein (IGFBP)-2, and IGFBP-3 in men in the United Kingdom
- (2012) Nicholas J. Young et al. CANCER CAUSES & CONTROL
- Insulin-Like Growth Factor Axis and Risk of Type 2 Diabetes in Women
- (2012) S. N. Rajpathak et al. DIABETES
- Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling
- (2012) X. Shen et al. MOLECULAR AND CELLULAR BIOLOGY
- Serum concentrations and tissue expression of components of insulin-like growth factor-axis in females with type 2 diabetes mellitus and obesity: The influence of very-low-calorie diet
- (2012) V. Touskova et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway
- (2012) Zhuo Li et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Acute regulation of IGF-I by alterations in post-exercise macronutrients
- (2011) E. B. Foster et al. AMINO ACIDS
- Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain
- (2011) Charles A. Galea et al. BIOCHIMIE
- DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression
- (2011) Shichun Zheng et al. NEURO-ONCOLOGY
- IGF2BP2 variations influence repaglinide response and risk of type 2 diabetes in Chinese population
- (2010) Qiong Huang et al. ACTA PHARMACOLOGICA SINICA
- Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene
- (2010) Kristina Hedbacker et al. Cell Metabolism
- IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription
- (2010) Matei Mireuta et al. GROWTH FACTORS
- Adipocytes IGFBP-2 Expression in Prepubertal Obese Children
- (2010) Maffeis Claudio et al. Obesity
- Lack of sex differences in the IGF-IGFBP response to ultra endurance exercise
- (2010) U. Berg et al. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
- Neuroendocrine Cancer-Specific Up-Regulating Mechanism of Insulin-Like Growth Factor Binding Protein-2 in Small Cell Lung Cancer
- (2009) Takuya Yazawa et al. AMERICAN JOURNAL OF PATHOLOGY
- The Association between Diet and Serum Concentrations of IGF-I, IGFBP-1, IGFBP-2, and IGFBP-3 in the European Prospective Investigation into Cancer and Nutrition
- (2009) F. L. Crowe et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Identification of Igf2, Igfbp2 and Enpp2 as Estrogen-Responsive Genes in Rat Hippocampus
- (2009) Chikari TAKEO et al. ENDOCRINE JOURNAL
- The Role of Insulin-Like Growth Factor (IGF) Binding Protein-2 in the Insulin-Mediated Decrease in IGF-I Bioactivity
- (2009) Ayman M. Arafat et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Serum Insulin-Like Growth Factor-1 Binding Proteins 1 and 2 and Mortality in Older Adults: The Health, Aging, and Body Composition Study
- (2009) Donglei Hu et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis
- (2009) Stephen B. Wheatcroft et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Evaluation of the Association of IGF2BP2 Variants With Type 2 Diabetes in French Caucasians
- (2008) K. Duesing et al. DIABETES
- IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus
- (2008) Yun-Sik Choi et al. GLIA
- Replication of Genome-Wide Association Studies of Type 2 Diabetes Susceptibility in Japan
- (2008) Yukio Horikawa et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Gαq interaction and protein kinase C-α/CaMKII activation in H9c2 cardiomyoblast cells
- (2008) Chun-Hsien Chu et al. JOURNAL OF ENDOCRINOLOGY
- PAPA-1 Is a Nuclear Binding Partner of IGFBP-2 and Modulates Its Growth-Promoting Actions
- (2008) Kenichi Miyako et al. MOLECULAR ENDOCRINOLOGY
- Post Genome-Wide Association Studies of Novel Genes Associated with Type 2 Diabetes Show Gene-Gene Interaction and High Predictive Value
- (2008) Stéphane Cauchi et al. PLoS One
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now