IGFBP-2 Directly Stimulates Osteoblast Differentiation

The role of insulin-like-growth factor binding protein 2 (IGFBP2) and phosphatase and tensin homologue (PTEN) in the regulation of myoblast differentiation and hypertrophy

(2013) Adam P. Sharples et al.   GROWTH HORMONE & IGF RESEARCH

Human Parathyroid Hormone Increases the mRNA Expression of the IGF System and Hematopoietic Growth Factors in Osteoblasts, but Does Not Influence Expression in Mesenchymal Stem Cells

(2013) Jong-Hwa Lee et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Insulin-like growth factor binding protein-2 and neurotrophin 3 synergize together to promote the expansion of hematopoietic cells ex vivo

(2012) Betül Çelebi et al.   CYTOKINE

Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase   and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling

(2012) X. Shen et al.   MOLECULAR AND CELLULAR BIOLOGY

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

(2012) Lingling Xian et al.   NATURE MEDICINE

Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading

(2011) Chandrasekhar Kesavan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells

(2011) H. Huynh et al.   BLOOD

The Heparin-binding Domain of IGFBP-2 Has Insulin-like Growth Factor Binding-independent Biologic Activity in the Growing Skeleton

(2011) Masanobu Kawai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-like growth factor-binding protein-2 is required for osteoclast differentiation

(2011) Victoria E DeMambro et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Crosstalks between integrin alpha 5 and IGF2/IGFBP2 signalling trigger human bone marrow-derived mesenchymal stromal osteogenic differentiation

(2010) Zahia Hamidouche et al.   BMC CELL BIOLOGY

Protein kinase D mediates the synergistic effects of BMP-7 and IGF-I on osteoblastic cell differentiation

(2010) Lee-Chuan C. Yeh et al.   GROWTH FACTORS

Basic fibroblast growth factor regulates IGF-I binding proteins in the clonal osteoblastic cell line MC3T3-E1

(2010) Marja M. Hurley et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation

(2010) Liang Chen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Subcellular localization of IRS-1 in IGF-I-mediated chondrogenic proliferation, differentiation and hypertrophy of bone marrow mesenchymal stem cells

(2009) Lara Longobardi et al.   GROWTH FACTORS

Candidate gene analysis of femoral neck trabecular and cortical volumetric bone mineral density in older men

(2009) Laura M Yerges et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Akt promotes BMP2-mediated osteoblast differentiation and bone development

(2009) A. Mukherjee et al.   JOURNAL OF CELL SCIENCE

Characterization of human cultured periosteal sheets expressing bone-forming potential:in vitroandin vivoanimal studies

(2009) Tomoyuki Kawase et al.   Journal of Tissue Engineering and Regenerative Medicine

Defined Carboxy-Terminal Fragments of Insulin-Like Growth Factor (IGF) Binding Protein-2 Exert Similar Mitogenic Activity on Cultured Rat Growth Plate Chondrocytes as IGF-I

(2008) Daniela Kiepe et al.   ENDOCRINOLOGY

Gender-Specific Changes in Bone Turnover and Skeletal Architecture inIgfbp-2-Null Mice

(2008) V. E. DeMambro et al.   ENDOCRINOLOGY

p66shc Negatively Regulates Insulin-Like Growth Factor I Signal Transduction via Inhibition of p52shc Binding to Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Substrate-1 Leading to Impaired Growth Factor Receptor-Bound Protein-2 Membrane Recruitment

(2008) Gang Xi et al.   MOLECULAR ENDOCRINOLOGY

The protein tyrosine phosphatase Rptpζ is expressed in differentiated osteoblasts and affects bone formation in mice

(2007) T. Schinke et al.   BONE

Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways

(2007) Angela Raucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY