Epigenetic Targets for Oligonucleotide Therapies of Pulmonary Arterial Hypertension
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epigenetic Targets for Oligonucleotide Therapies of Pulmonary Arterial Hypertension
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 23, Pages 9222
Publisher
MDPI AG
Online
2020-12-04
DOI
10.3390/ijms21239222
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Current and future treatments of pulmonary arterial hypertension
- (2020) Natascha Sommer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Correlation Between Single Nucleotide Polymorphisms of the rs664589 Locus in the Long-Chain Noncoding RNA Lung Adenocarcinoma Metastasis-Associated Gene 1, Hypertension, and Its Mechanism
- (2020) Xianyu Mou et al. Genetic Testing and Molecular Biomarkers
- The promise and challenge of therapeutic genome editing
- (2020) Jennifer A. Doudna NATURE
- Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension
- (2020) François Potus et al. CIRCULATION
- Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
- (2020) Ashley E. Lepack et al. SCIENCE
- siRNA based drug design, quality, delivery and clinical translation
- (2020) Md Abdus Subhan et al. Nanomedicine-Nanotechnology Biology and Medicine
- The BET Bromodomain Inhibitor I-BET-151 Induces Structural and Functional Alterations of the Heart Mitochondria in Healthy Male Mice and Rats
- (2019) Jérôme Piquereau et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension
- (2019) Diederik E Van der Feen et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- NSD2 silencing alleviates pulmonary arterial hypertension by inhibiting trehalose metabolism and autophagy
- (2019) Xue-liang Zhou et al. CLINICAL SCIENCE
- Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells
- (2019) Mahendran Chinnappan et al. Scientific Reports
- Epigenetics and vascular diseases
- (2019) Matthew S. Stratton et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- LncRNA Tug1 involves in the pulmonary vascular remodeling in mice with hypoxic pulmonary hypertension via the microRNA-374c-mediated Foxc1
- (2019) Lei Yang et al. LIFE SCIENCES
- Targeting histone acetylation in pulmonary hypertension and right ventricular hypertrophy
- (2019) Prakash Chelladurai et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Long Noncoding RNA LnRPT Puts the Brakes on Pulmonary Artery Smooth Muscle Cell Proliferation
- (2018) William M. Oldham AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The Long Noncoding RNA LnRPT Is Regulated by PDGF-BB and Modulates the Proliferation of Pulmonary Artery Smooth Muscle Cells
- (2018) Jidong Chen et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Epigenetic Regulation and Its Therapeutic Potential in Pulmonary Hypertension
- (2018) Yu Wang et al. Frontiers in Pharmacology
- Insights on the epigenetic mechanisms underlying pulmonary arterial hypertension
- (2018) R.C.P. Luna et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- Long noncoding RNA Hoxaas3 contributes to hypoxia-induced pulmonary artery smooth muscle cell proliferation
- (2018) Hongyue Zhang et al. CARDIOVASCULAR RESEARCH
- Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
- (2018) Marc Humbert et al. EUROPEAN RESPIRATORY JOURNAL
- Clinical trial design and new therapies for pulmonary arterial hypertension
- (2018) Olivier Sitbon et al. EUROPEAN RESPIRATORY JOURNAL
- Long noncoding RNA UCA1 promotes the proliferation of hypoxic human pulmonary artery smooth muscle cells
- (2018) Tian-Tian Zhu et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2
- (2017) Richard Y. Kim et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The Role of Nuclear Receptor–Binding SET Domain Family Histone Lysine Methyltransferases in Cancer
- (2017) Richard L. Bennett et al. Cold Spring Harbor Perspectives in Medicine
- The cancer theory of pulmonary arterial hypertension
- (2017) Olivier Boucherat et al. Pulmonary Circulation
- HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension
- (2017) Olivier Boucherat et al. Scientific Reports
- Análisis de la metilación de la región promotora del gen BMPR2 en pacientes con hipertensión arterial pulmonar
- (2016) Guillermo Pousada et al. ARCHIVOS DE BRONCONEUMOLOGIA
- World Health Organization Group I Pulmonary Hypertension
- (2016) Kurt W. Prins et al. CARDIOLOGY CLINICS
- Inhibition of histone deacetylase reduces transcription of NADPH oxidases and ROS production and ameliorates pulmonary arterial hypertension
- (2016) Feng Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Long noncoding RNA expression profiles of hypoxic pulmonary hypertension rat model
- (2016) Xiaohua Wang et al. GENE
- Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension
- (2016) Sharon Mumby et al. RESPIROLOGY
- Análisis de la metilación de la región promotora del gen BMPR2 en pacientes con hipertensión arterial pulmonar
- (2016) Guillermo Pousada et al. ARCHIVOS DE BRONCONEUMOLOGIA
- Transcription Factors, Transcriptional Coregulators, and Epigenetic Modulation in the Control of Pulmonary Vascular Cell Phenotype: Therapeutic Implications for Pulmonary Hypertension (2015 Grover Conference Series)
- (2016) Soni S. Pullamsetti et al. Pulmonary Circulation
- Reversal of MicroRNA Dysregulation in an Animal Model of Pulmonary Hypertension
- (2016) Igor B. Gubrij et al. PLoS One
- Inflammation in chronic thromboembolic pulmonary hypertension: accomplice or bystander in altered angiogenesis?
- (2015) Paul M. Hassoun EUROPEAN RESPIRATORY JOURNAL
- Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension
- (2015) Jared M. McLendon et al. JOURNAL OF CONTROLLED RELEASE
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
- (2015) Norihiro Kato et al. NATURE GENETICS
- Epigenetic targets for novel therapies of lung diseases
- (2015) Brian S. Comer et al. PHARMACOLOGY & THERAPEUTICS
- Development and classes of epigenetic drugs for cancer
- (2014) Dashyant Dhanak et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth
- (2014) Katharina M. Michalik et al. CIRCULATION RESEARCH
- BET-ting on chromatin-based therapeutics for heart failure
- (2014) Saptarsi M. Haldar et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
- (2014) Ezgi Hacisuleyman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Anticipated Classes of New Medications and Molecular Targets for Pulmonary Arterial Hypertension
- (2014) Nicholas W. Morrell et al. Pulmonary Circulation
- lincRNAs: Genomics, Evolution, and Mechanisms
- (2013) Igor Ulitsky et al. CELL
- Histone deacetylases in cardiac fibrosis: Current perspectives for therapy
- (2013) Hui Tao et al. CELLULAR SIGNALLING
- MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts
- (2013) Daren Wang et al. CIRCULATION RESEARCH
- Targeting long non-coding RNAs in cancers: Progress and prospects
- (2013) Chi Han Li et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells
- (2013) Kang Kang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma
- (2013) Yongqing Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension
- (2013) Rubin M. Tuder et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Targeting long non-coding RNA to therapeutically upregulate gene expression
- (2013) Claes Wahlestedt NATURE REVIEWS DRUG DISCOVERY
- Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction
- (2013) Andrii Rudenko et al. NEURON
- Circulating miRNAs as Potential Marker for Pulmonary Hypertension
- (2013) Chuanyu Wei et al. PLoS One
- Integrated Expression Profiles of mRNA and miRNA in Polarized Primary Murine Microglia
- (2013) Robert W. Freilich et al. PLoS One
- Safety profile of RNAi nanomedicines
- (2012) Scott A. Barros et al. ADVANCED DRUG DELIVERY REVIEWS
- Cytotoxic Cells and Granulysin in Pulmonary Arterial Hypertension and Pulmonary Veno-occlusive Disease
- (2012) Frédéric Perros et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Genome Regulation by Long Noncoding RNAs
- (2012) John L. Rinn et al. Annual Review of Biochemistry
- Noncoding Transcription at Enhancers: General Principles and Functional Models
- (2012) Gioacchino Natoli et al. Annual Review of Genetics
- DNA methylation inhibitors in cancer: Recent and future approaches
- (2012) Christina Gros et al. BIOCHIMIE
- Histone Deacetylation Inhibition in Pulmonary Hypertension
- (2012) Lan Zhao et al. CIRCULATION
- MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension
- (2012) Victoria N. Parikh et al. CIRCULATION
- A Role for miR-145 in Pulmonary Arterial Hypertension
- (2012) Paola Caruso et al. CIRCULATION RESEARCH
- AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension
- (2012) Matthias Brock et al. EUROPEAN HEART JOURNAL
- Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells
- (2012) Weishi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression
- (2012) Clemens L. Bockmeyer et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Control of somatic tissue differentiation by the long non-coding RNA TINCR
- (2012) Markus Kretz et al. NATURE
- An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension
- (2012) Jongmin Kim et al. NATURE MEDICINE
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Mir-206 Regulates Pulmonary Artery Smooth Muscle Cell Proliferation and Differentiation
- (2012) Samuel Jalali et al. PLoS One
- Antisense oligonucleotide therapeutics for inherited neurodegenerative diseases
- (2012) Amber L. Southwell et al. TRENDS IN MOLECULAR MEDICINE
- Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension
- (2012) Kevin White et al. Pulmonary Circulation
- Inhibition of MicroRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension
- (2011) Soni S. Pullamsetti et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Drugs Targeting Epigenetic Histone Acetylation in Vascular Smooth Muscle Cells for Restenosis and Atherosclerosis
- (2011) Rama Natarajan ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Regulation of chromatin by histone modifications
- (2011) Andrew J Bannister et al. CELL RESEARCH
- Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
- (2011) M. N. Cabili et al. GENES & DEVELOPMENT
- Inhibition of house dust mite–induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment
- (2011) Adam Collison et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Role for miR-204 in human pulmonary arterial hypertension
- (2011) Audrey Courboulin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension
- (2011) M. Li et al. JOURNAL OF IMMUNOLOGY
- Cancer epigenetics reaches mainstream oncology
- (2011) Manuel Rodríguez-Paredes et al. NATURE MEDICINE
- RNA splicing control
- (2011) Xinying Zong et al. RNA Biology
- Dynamic Changes in Lung MicroRNA Profiles During the Development of Pulmonary Hypertension due to Chronic Hypoxia and Monocrotaline
- (2010) Paola Caruso et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension
- (2010) Stephen L. Archer et al. CIRCULATION
- Epigenetic regulation of the endothelial nitric oxide synthase gene in persistent pulmonary hypertension of the newborn rat
- (2010) Xue-Feng Xu et al. JOURNAL OF HYPERTENSION
- Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
- (2010) Jian Feng et al. NATURE NEUROSCIENCE
- Interleukin-6 Modulates the Expression of the Bone Morphogenic Protein Receptor Type II Through a Novel STAT3–microRNA Cluster 17/92 Pathway
- (2009) Matthias Brock et al. CIRCULATION RESEARCH
- Prostacyclin Inhibits IFN- -Stimulated Cytokine Expression by Reduced Recruitment of CBP/p300 to STAT1 in a SOCS-1-Independent Manner
- (2009) D. Strassheim et al. JOURNAL OF IMMUNOLOGY
- Linking DNA methylation and histone modification: patterns and paradigms
- (2009) Howard Cedar et al. NATURE REVIEWS GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More