In the Right Place at the Right Time: miRNAs as Key Regulators in Developing Axons

Spatiotemporal regulation of GSK3β levels by miRNA-26a controls axon development in cortical neurons

(2020) Cristiano Lucci et al.   DEVELOPMENT

Axonal precursor mi RNA s hitchhike on endosomes and locally regulate the development of neural circuits

(2020) Eloina Corradi et al.   EMBO JOURNAL

Local mRNA translation in long-term maintenance of axon health and function

(2020) Eunjin Kim et al.   CURRENT OPINION IN NEUROBIOLOGY

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

(2019) Jean-Michel Cioni et al.   CELL

MicroRNAs and Regeneration in Animal Models of CNS Disorders

(2019) Tamara Roitbak   NEUROCHEMICAL RESEARCH

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments

(2019) Anne-Sophie Hafner et al.   SCIENCE

Local translation in neurons: visualization and function

(2019) Christine E. Holt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

Neuronal RNP granules: from physiological to pathological assemblies

(2018) Fabienne De Graeve et al.   BIOLOGICAL CHEMISTRY

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

(2018) Benjamin Kleaveland et al.   CELL

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Aβ 1–42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons

(2018) Chandler A Walker et al.   EMBO REPORTS

MicroRNA degradation by a conserved target RNA regulates animal behavior

(2018) Angelo Bitetti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

(2018) Roberta Cagnetta et al.   NEURON

Locally translated mTOR controls axonal local translation in nerve injury

(2018) Marco Terenzio et al.   SCIENCE

MicroRNA degradation by a conserved target RNA regulates animal behavior

(2018) Angelo Bitetti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activity-Dependent Pre-miR-134 Dendritic Localization Is Required for Hippocampal Neuron Dendritogenesis

(2018) Federico Zampa et al.   Frontiers in Molecular Neuroscience

Evolutionary divergence of Brain-specific precursor miRNAs drives efficient processing and production of mature miRNAs in human

(2018) Sajib Chakraborty et al.   NEUROSCIENCE

miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance

(2018) Tao Yang et al.   Cell Reports

Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

(2018) Noga Gershoni-Emek et al.   Frontiers in Molecular Neuroscience

Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development

(2018) Tomasz J. Nowakowski et al.   NATURE NEUROSCIENCE

RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo

(2017) Hovy Ho-Wai Wong et al.   NEURON

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

(2017) Anaïs Bellon et al.   Cell Reports

Accumulating Evidence for Axonal Translation in Neuronal Homeostasis

(2017) Emily L. Spaulding et al.   Frontiers in Neuroscience

ALS Along the Axons – Expression of Coding and Noncoding RNA Differs in Axons of ALS models

(2017) Nimrod Rotem et al.   Scientific Reports

Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons

(2017) Florian Ströhl et al.   Scientific Reports

Dynamic Axonal Translation in Developing and Mature Visual Circuits

(2016) Toshiaki Shigeoka et al.   CELL

Axonal localization and mitochondrial association of precursor microRNA 338

(2016) Jose Norberto S. Vargas et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA-338 Attenuates Cortical Neuronal Outgrowth by Modulating the Expression of Axon Guidance Genes

(2016) Aron Kos et al.   MOLECULAR NEUROBIOLOGY

Distribution of miRNA expression across human tissues

(2016) Nicole Ludwig et al.   NUCLEIC ACIDS RESEARCH

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer’s Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7)

(2016) Yuhai Zhao et al.   Genes

Membrane-Coupled mRNA Trafficking in Fungi

(2015) Carl Haag et al.   Annual Review of Microbiology

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

(2015) Henry Heberle et al.   BMC BIOINFORMATICS

MicroRNAs in the axon locally mediate the effects of chondroitin sulfate proteoglycans and cGMP on axonal growth

(2015) Yi Zhang et al.   Developmental Neurobiology

Identification of precursor microRNAs within distal axons of sensory neuron

(2015) Hak Hee Kim et al.   JOURNAL OF NEUROCHEMISTRY

Direct visualization of newly synthesized target proteins in situ

(2015) Susanne tom Dieck et al.   NATURE METHODS

FMRP-Mediated Axonal Delivery of miR-181d Regulates Axon Elongation by Locally Targeting Map1b and Calm1

(2015) Bin Wang et al.   Cell Reports

Dynamic Change and Target Prediction of Axon-Specific MicroRNAs in Regenerating Sciatic Nerve

(2015) Monichan Phay et al.   PLoS One

MicroRNA-132 Is Enriched in Developing Axons, Locally Regulates Rasa1 mRNA, and Promotes Axon Extension

(2014) M. L. Hancock et al.   JOURNAL OF NEUROSCIENCE

In the right place at the right time: visualizing and understanding mRNA localization

(2014) Adina R. Buxbaum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of axon-enriched MicroRNAs localized to growth cones of cortical neurons

(2013) Yukio Sasaki et al.   Developmental Neurobiology

Endosomal transport of septin mRNA and protein indicates local translation on endosomes and is required for correct septin filamentation

(2013) Sebastian Baumann et al.   EMBO REPORTS

The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134

(2013) S. Bicker et al.   GENES & DEVELOPMENT

Intra-axonal Synthesis of Eukaryotic Translation Initiation Factors Regulates Local Protein Synthesis and Axon Growth in Rat Sympathetic Neurons

(2013) A. N. Kar et al.   JOURNAL OF NEUROSCIENCE

The MicroRNA-17-92 Cluster Enhances Axonal Outgrowth in Embryonic Cortical Neurons

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

miR-26a promotes neurite outgrowth by repressing PTEN expression

(2013) BAOGUO LI et al.   Molecular Medicine Reports

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Mitochondria Coordinate Sites of Axon Branching through Localized Intra-axonal Protein Synthesis

(2013) Mirela Spillane et al.   Cell Reports

Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development

(2013) Maria Skamagki et al.   Cell Reports

MicroRNA-338 regulates the axonal expression of multiple nuclear-encoded mitochondrial mRNAs encoding subunits of the oxidative phosphorylation machinery

(2012) Armaz Aschrafi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kinesin-3 and dynein mediate microtubule-dependent co-transport of mRNPs and endosomes

(2012) S. Baumann et al.   JOURNAL OF CELL SCIENCE

Cooperative Activation of PI3K by Ras and Rho Family Small GTPases

(2012) Hee Won Yang et al.   MOLECULAR CELL

microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons

(2012) Federico Dajas-Bailador et al.   NATURE NEUROSCIENCE

Intra-axonal Translation of SMAD1/5/8 Mediates Retrograde Regulation of Trigeminal Ganglia Subtype Specification

(2012) Sheng-Jian Ji et al.   NEURON

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain

(2012) Miao He et al.   NEURON

The lin-4 MicroRNA Targets the LIN-14 Transcription Factor to Inhibit Netrin-Mediated Axon Attraction

(2012) Y. Zou et al.   Science Signaling

Pathologies of axonal transport in neurodegenerative diseases

(2012) Xin-An Liu et al.   Translational Neuroscience

Deep sequencing analysis of the developing mouse brain reveals a novel microRNA

(2011) King-Hwa Ling et al.   BMC GENOMICS

Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling

(2011) Ravi S. Muddashetty et al.   MOLECULAR CELL

miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones

(2011) Marie-Laure Baudet et al.   NATURE NEUROSCIENCE

Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

(2011) Alison A Staton et al.   Nature Protocols

Bicaudal-D Regulates Fragile X Mental Retardation Protein Levels, Motility, and Function during Neuronal Morphogenesis

(2010) Ambra Bianco et al.   CURRENT BIOLOGY

Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs

(2010) K. H. Zivraj et al.   JOURNAL OF NEUROSCIENCE

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

(2010) Catia Andreassi et al.   NATURE NEUROSCIENCE

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

(2010) Dieter Edbauer et al.   NEURON

Identification and quantitative analyses of microRNAs located in the distal axons of sympathetic neurons

(2010) O. Natera-Naranjo et al.   RNA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

MicroRNA Implications across Neurodevelopment and Neuropathology

(2009) Sabata Martino et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

Three distinct RNA localization mechanisms contribute to oocyte polarity establishment in the cnidarian Clytia hemisphærica

(2008) Aldine Amiel et al.   DEVELOPMENTAL BIOLOGY

A Direct Role for FMRP in Activity-Dependent Dendritic mRNA Transport Links Filopodial-Spine Morphogenesis to Fragile X Syndrome

(2008) Jason B. Dictenberg et al.   DEVELOPMENTAL CELL

MicroRNA-338 Regulates Local Cytochrome c Oxidase IV mRNA Levels and Oxidative Phosphorylation in the Axons of Sympathetic Neurons

(2008) A. Aschrafi et al.   JOURNAL OF NEUROSCIENCE

Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

(2008) Llewellyn J. Cox et al.   NATURE CELL BIOLOGY

Dynamic Association of the Fragile X Mental Retardation Protein as a Messenger Ribonucleoprotein between Microtubules and Polyribosomes

(2007) Houping Wang et al.   MOLECULAR BIOLOGY OF THE CELL