Novel 3D preclinical model systems with primary human liver cells: recent progresses, applications and future prospects

Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity

(2020) Catherine C. Bell et al.   ARCHIVES OF TOXICOLOGY

Novel patient-derived preclinical models of liver cancer

(2020) Erin Bresnahan et al.   JOURNAL OF HEPATOLOGY

3D Spheroids with Primary Human Liver Cells and Differential Roles of Kupffer Cells in Drug-Induced Liver Injury

(2020) Feng Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Next generation in vitro primary hepatic cell test systems—their suitability as an alternative to in vivo testing?

(2020) Ali Kermanizadeh et al.   Hepatobiliary Surgery and Nutrition

Optimization of 3D hydrogel microenvironment for enhanced hepatic functionality of primary human hepatocytes

(2020) Ho‐Joon Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Bioprinting of in vitro tumor models for personalized cancer treatment: a review

(2020) Shuangshuang Mao et al.   Biofabrication

Patient-derived model systems and the development of next-generation anticancer therapeutics

(2020) Nikolaus Krall et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Application of a 3D Bioprinted Hepatocellular Carcinoma Cell Model in Antitumor Drug Research

(2020) Lejia Sun et al.   Frontiers in Oncology

Three-dimensional bio-printing of primary human hepatocellular carcinoma for personalized medicine

(2020) Feihu Xie et al.   BIOMATERIALS

Non-alcoholic fatty liver disease (NAFLD) and the quest for effective treatments

(2019) Kessarin Thanapirom et al.   HEPATOBILIARY SURGERY AND NUTRITION

Establishment of a hepatocellular carcinoma patient‐derived xenograft platform and its application in biomarker identification

(2019) Bo Hu et al.   INTERNATIONAL JOURNAL OF CANCER

The future of organ-oriented research and treatment

(2019) Qiang Zhao et al.   Hepatobiliary Surgery and Nutrition

3D bioprinting of tissues and organs for regenerative medicine

(2018) Sanjairaj Vijayavenkataraman et al.   ADVANCED DRUG DELIVERY REVIEWS

A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX

(2018) Xiang Li et al.   LAB ON A CHIP

Human hepatic 3D spheroids as a model for steatosis and insulin resistance

(2018) Mikael Kozyra et al.   Scientific Reports

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

(2018) Sandro Nuciforo et al.   Cell Reports

Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture

(2018) Weng Chuan Peng et al.   CELL

Circulating Tumor Cell-Derived Pre-Clinical Models for Personalized Medicine

(2018) Marta Tellez-Gabriel et al.   Cancers

Patient-derived xenografts, a multi-faceted in vivo model enlightening research on rare liver cancer biology

(2017) Massimo Moro et al.   HEPATOBILIARY SURGERY AND NUTRITION