Inactivated STAT5 pathway underlies a novel inhibitory role of EBF1 in chronic lymphocytic leukemia
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Title
Inactivated STAT5 pathway underlies a novel inhibitory role of EBF1 in chronic lymphocytic leukemia
Authors
Keywords
Chronic lymphocytic leukemia cells, Early B-Cell factor-1, Signal transducers and activators of transcription 5 pathway, Proliferation, Apoptosis
Journal
EXPERIMENTAL CELL RESEARCH
Volume 398, Issue 1, Pages 112371
Publisher
Elsevier BV
Online
2020-11-12
DOI
10.1016/j.yexcr.2020.112371
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Note: Only part of the references are listed.- Treatment-naive CLL: lessons from phase 2 and phase 3 clinical trials
- (2019) Jennifer A. Woyach BLOOD
- Adherence to the Western, Prudent, and Mediterranean dietary patterns and chronic lymphocytic leukemia in the MCC-Spain study.
- (2018) Marta Solans et al. HAEMATOLOGICA
- Chronic lymphocytic leukaemia
- (2018) Michael Hallek et al. LANCET
- Adherence to the Western, Prudent, and Mediterranean dietary patterns and chronic lymphocytic leukemia in the MCC-Spain study.
- (2018) Marta Solans et al. HAEMATOLOGICA
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis
- (2017) S J Welsh et al. LEUKEMIA
- Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation
- (2017) Kalpesh D. Mahajan et al. Biotechnology Journal
- Early B-cell factor 1 (EBF1) is critical for transcriptional control of SLAMF1 gene in human B cells
- (2016) Anton M. Schwartz et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
- (2016) R. Salvador-Gallego et al. EMBO JOURNAL
- GIFT4 fusokine converts leukemic B cells into immune helper cells
- (2016) Jiusheng Deng et al. Journal of Translational Medicine
- Prognostic significance of signal transducer and activator of transcription 5 and 5b expression in Epstein-Barr virus-positive patients with chronic lymphocytic leukemia
- (2016) Panagiotis T. Diamantopoulos et al. Cancer Medicine
- Ebf1 in DNA repair and leukemogenesis
- (2015) K. Georgopoulos BLOOD
- Inhibition of pulmonary cancer progression by epidermal growth factor receptor-targeted transfection with Bcl-2 and survivin siRNAs
- (2015) Y K Lee et al. CANCER GENE THERAPY
- Effects of gemcitabine on radiosensitization, apoptosis, and Bcl-2 and Bax protein expression in human pancreatic cancer xenografts in nude mice
- (2015) Z.T. Shen et al. GENETICS AND MOLECULAR RESEARCH
- Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia
- (2015) Yan-Fang Tao et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
- (2015) Yamunadevi Subburaj et al. Nature Communications
- Ginsenoside Rg1 Induces Apoptosis through Inhibition of the EpoR-Mediated JAK2/STAT5 Signalling Pathway in the TF-1/Epo Human Leukemia Cell Line
- (2014) Jing Li et al. Asian Pacific Journal of Cancer Prevention
- Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy
- (2014) S. Bibi et al. HAEMATOLOGICA
- The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function
- (2014) Sören Boller et al. IMMUNOLOGICAL REVIEWS
- Comparative study of different procedures for the separation of peripheral blood mononuclear cells in cytokine-induced killer cell immunotherapy for hepatocarcinoma
- (2014) Hui Liu et al. TUMOR BIOLOGY
- Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment
- (2013) Michael Hallek AMERICAN JOURNAL OF HEMATOLOGY
- The Pathogenesis of Chronic Lymphocytic Leukemia
- (2013) Suping Zhang et al. Annual Review of Pathology-Mechanisms of Disease
- Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)
- (2013) J. A. Woyach et al. BLOOD
- Early B-cell Factor 1 Regulates the Expansion of B-cell Progenitors in a Dose-dependent Manner
- (2013) Josefine Åhsberg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ebf1 and c-Myb Repress Rag Transcription Downstream of Stat5 during Early B Cell Development
- (2013) G. A. Timblin et al. JOURNAL OF IMMUNOLOGY
- Combination of YM155, a survivin suppressant with a STAT3 inhibitor: A new strategy to treat diffuse large B-cell lymphoma
- (2013) Naoki Kaneko et al. LEUKEMIA RESEARCH
- Identification of a STAT5 Target Gene, Dpf3, Provides Novel Insights in Chronic Lymphocytic Leukemia
- (2013) Marina Theodorou et al. PLoS One
- The role of STAT5 in lymphocyte development and transformation
- (2012) Lynn M Heltemes-Harris et al. CURRENT OPINION IN IMMUNOLOGY
- Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells
- (2012) I. Gyory et al. GENES & DEVELOPMENT
- Essential role of EBF1 in the generation and function of distinct mature B cell types
- (2012) Bojan Vilagos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B-lineage transcription factors and cooperating gene lesions required for leukemia development
- (2012) E Tijchon et al. LEUKEMIA
- Ebf1orPax5haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia
- (2011) Lynn M. Heltemes-Harris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Granulocyte macrophage-colony stimulating factor shows anti-apoptotic activity in neural progenitor cells via JAK/STAT5-Bcl-2 pathway
- (2010) Jung Kyoung Choi et al. APOPTOSIS
- Age at diagnosis and the utility of prognostic testing in patients with chronic lymphocytic leukemia
- (2010) Tait D. Shanafelt et al. CANCER
- The associations of Janus kinase-2 (JAK2) A830G polymorphism and the treatment outcomes in patients with acute myeloid leukemia
- (2010) Yuejiao Zhong et al. LEUKEMIA & LYMPHOMA
- Clinical significance of Cox-2, Survivin and Bcl-2 expression in hepatocellular carcinoma (HCC)
- (2010) Yu Yang et al. MEDICAL ONCOLOGY
- Stat5 Promotes Survival of Mammary Epithelial Cells through Transcriptional Activation of a Distinct Promoter in Akt1
- (2010) B. A. Creamer et al. MOLECULAR AND CELLULAR BIOLOGY
- Targeting Janus Kinase 2 in Her2/neu-Expressing Mammary Cancer: Implications for Cancer Prevention and Therapy
- (2009) K. Sakamoto et al. CANCER RESEARCH
- Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development
- (2009) Stephen Malin et al. NATURE IMMUNOLOGY
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