Atractylenolides, essential components of Atractylodes-based traditional herbal medicines: Antioxidant, anti-inflammatory and anticancer properties

A panoramic review of IL-6: Structure, pathophysiological roles and inhibitors

(2020) Sukhvir Kaur et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs

(2020) Hui Luo et al.   Chinese Journal of Integrative Medicine

Anti-Tumor Activity of Atractylenolide I in Human Colon Adenocarcinoma In Vitro

(2020) Ka Chan et al.   MOLECULES

Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling

(2020) Kuilong Wang et al.   PHYTOMEDICINE

The Anticancer Effects of Atractylenolide III Associate With the Downregulation of Jak3/Stat3-Dependent IDO Expression

(2020) Jun-bao Liu et al.   Frontiers in Pharmacology

Yinchenzhufu decoction protects against alpha-naphthylisothiocyanate-induced acute cholestatic liver injury in mice by ameliorating disordered bile acid homeostasis and inhibiting inflammatory responses

(2020) Guo-Feng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Atractylenolide I Induces Apoptosis and Suppresses Glycolysis by Blocking the JAK2/STAT3 Signaling Pathway in Colorectal Cancer Cells

(2020) Yanxi Li et al.   Frontiers in Pharmacology

An Integrated Pharmacology-Based Analysis for Antidepressant Mechanism of Chinese Herbal Formula Xiao-Yao-San

(2020) Naijun Yuan et al.   Frontiers in Pharmacology

UPLC-Q-Exactive Orbitrap MS Analysis for Identification of Lipophilic Components in Citri Sarcodactylis Fructus from Different Origins in China Using Supercritical CO2 Fluid Extraction Method

(2020) Chengxiao Fu et al.   ACS Omega

Atractylenolide II prevents radiation damage via MAPKp38/Nrf2 signaling pathway

(2020) Changyan Xiao et al.   BIOCHEMICAL PHARMACOLOGY

Ling-gui-zhu-gan decoction alleviates hepatic steatosis through SOCS2 modification by N6-methyladenosine

(2020) Yanqi Dang et al.   BIOMEDICINE & PHARMACOTHERAPY

Simultaneous determination of six components of Danzhi Xiaoyao Pill in beagle plasma by HPLC-MS/MS and a study of pharmacokinetic of paeoniflorin and geniposide after single-dose administration

(2020) Yong-liang Zhu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Exploration of chemical composition and absorption characteristics of Chaigui granules based on UHPLC-Q-orbitrap-MS/MS

(2020) Xiaoxia Gao et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Chemical characterisation and quantification of the major constituents in the Chinese herbal formula Jian‐Pi‐Yi‐Shen pill by UPLC‐Q‐TOF‐MS/MS and HPLC‐QQQ‐MS/MS

(2020) Fochang Wang et al.   PHYTOCHEMICAL ANALYSIS

Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies

(2020) Lijie Zhai et al.   Frontiers in Immunology

Transfer of metastatic traits via miR‐200c in extracellular vesicles derived from colorectal cancer stem cells is inhibited by atractylenolide I

(2020) Dongxin Tang et al.   Clinical and Translational Medicine

Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy

(2020) Chao Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Evaluation of the mechanism of Danggui-Shaoyao-San in regulating the metabolome of nephrotic syndrome based on urinary metabonomics and bioinformatics approaches

(2020) Yunlai Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Embryotoxicity evaluation of atractylodin and β-eudesmol using the zebrafish model

(2020) Gyem Tshering et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Rapid discovery of chemical constituents and absorbed components in rat serum after oral administration of Fuzi-Lizhong pill based on high-throughput HPLC-Q-TOF/MS analysis

(2019) Zhen Zhang et al.   Chinese Medicine

Response of Bioactive Metabolite and Biosynthesis Related Genes to Methyl Jasmonate Elicitation in Codonopsis pilosula

(2019) Jiao-jiao Ji et al.   MOLECULES

HBD Inhibits the Development of Colitis-Associated Cancer in Mice via the IL-6R/STAT3 Signaling Pathway

(2019) Song Deng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-Inflammatory Compounds from Atractylodes macrocephala

(2019) Dawoon Jeong et al.   MOLECULES

Quality evaluation of decoction pieces of Rhizoma Atractylodis Macrocephalae by near infrared spectroscopy coupled with chemometrics

(2019) Xiaoyi Chen et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Establishment of a mouse model of cancer cachexia with spleen deficiency syndrome and the effects of atractylenolide I

(2019) Wan-li Zhang et al.   ACTA PHARMACOLOGICA SINICA

Gut microbial modulation in the treatment of chemotherapy-induced diarrhea with Shenzhu Capsule

(2019) Jing Wang et al.   BMC Complementary and Alternative Medicine

A review of pharmacological and clinical studies on the application of Shenling Baizhu San in treatment of Ulcerative colitis

(2019) Qianqian Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

The effect of Xiang-Sha-Liu-Jun-Zi tang (XSLJZT) on irritable bowel syndrome: A randomized, double-blind, placebo-controlled trial

(2019) Yi-Sing Shih et al.   JOURNAL OF ETHNOPHARMACOLOGY

In vivo metabolic profiles of Bu-Zhong-Yi-Qi-Tang, a famous traditional Chinese medicine prescription, in rats by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

(2019) Liufang Hu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia

(2019) Kecheng Zhou et al.   PHYTOMEDICINE

Geographic authentication of the traditional Chinese medicine Atractylodes macrocephala Koidz. (Baizhu) using stable isotope and multielement analyses

(2019) Ling Hu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Polysaccharide extracted from Atractylodes macrocephala Koidz (PAMK) induce apoptosis in transplanted H22 cells in mice

(2019) Ying-ying Feng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Atractylodis Rhizoma Alba Attenuates Neuroinflammation in BV2 Microglia upon LPS Stimulation by Inducing HO-1 Activity and Inhibiting NF-κB and MAPK

(2019) Yun Hee Jeong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Shen-Ling-Bai-Zhu-San alleviates functional dyspepsia in rats and modulates the composition of the gut microbiota

(2019) Shaobao Zhang et al.   NUTRITION RESEARCH

Hochu-Ekki-To Improves Motor Function in an Amyotrophic Lateral Sclerosis Animal Model

(2019) Mudan Cai et al.   Nutrients

Screening for Potential Active Components of Fangji Huangqi Tang on the Treatment of Nephrotic Syndrome by Using Integrated Metabolomics Based on “Correlations Between Chemical and Metabolic Profiles”

(2019) Xiao Liu et al.   Frontiers in Pharmacology

Integrative serum metabolomics and network analysis on mechanisms exploration of Ling-Gui-Zhu-Gan Decoction on doxorubicin-induced heart failure mice

(2019) Xu Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Xiao-Yao-San reduces blood-brain barrier injury induced by chronic stress in vitro and vivo via glucocorticoid receptor-mediated upregulation of Occludin

(2019) Shaolong Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Small molecules for mesenchymal stem cell fate determination

(2019) Yu-Hao Cheng et al.   World Journal of Stem Cells

The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I

(2018) Xiu-Qiong Fu et al.   EXPERIMENTAL DERMATOLOGY

Glycoproteins isolated from Atractylodes macrocephala Koidz improve protective immune response induction in a mouse model

(2018) Kyoung-A. Kim et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Quality Control of the Fuzi Lizhong Pill Through Simultaneous Determination of 16 Major Bioactive Constituents by RRLC–MS-MS

(2018) Yun-zhuo Dong et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Effects of processing adjuvants on traditional Chinese herbs

(2018) Lin-Lin Chen et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Simultaneous Determination of the Traditional Herbal Formula Ukgansan and the In Vitro Antioxidant Activity of Ferulic Acid as an Active Compound

(2018) Yu Kim et al.   MOLECULES

Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation

(2018) Lu Li et al.   Journal of Cell Communication and Signaling

Repression of PDK1- and LncRNA HOTAIR-Mediated EZH2 Gene Expression Contributes to the Enhancement of Atractylenolide 1 and Erlotinib in the Inhibition of Human Lung Cancer Cells

(2018) Qian Xiao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mucosal immunomodulatory evaluation and chemical profile elucidation of a classical traditional Chinese formula, Bu-Zhong-Yi-Qi-Tang

(2018) Liyin Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review

(2018) Bo Zhu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ameliorative effect of Xiaoyao-jieyu-san on post-stroke depression and its potential mechanisms

(2018) Changde Wang et al.   Journal of Natural Medicines

LC-ESI-MS/MS method for simultaneous determination of eleven bioactive compounds in rat plasma after oral administration of Ling-Gui-Zhu-Gan Decoction and its application to a pharmacokinetics study

(2018) Bin Ji et al.   TALANTA

Systems pharmacology reveals the unique mechanism features of Shenzhu Capsule for treatment of ulcerative colitis in comparison with synthetic drugs

(2018) Wuwen Feng et al.   Scientific Reports

System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of Zhi-zhu Wan for Functional Dyspepsia

(2018) Chun Wang et al.   Frontiers in Pharmacology

Enhancement of neuroprotective activity of Sagunja-tang by fermentation with lactobacillus strains

(2018) Nam-Hui Yim et al.   BMC Complementary and Alternative Medicine

A High Throughput Three-step Ultra-performance Liquid Chromatography Tandem Mass Spectrometry Method to Study Metabolites of Atractylenolide-III

(2018) Zhihui Jiang et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

An ethanol extract of the rhizome of Atractylodes chinensis exerts anti-gastritis activities and inhibits Akt/NF-κB signaling

(2018) Muhammad Jahangir Hossen et al.   JOURNAL OF ETHNOPHARMACOLOGY

UPLC-MS/MS of Atractylenolide I, Atractylenolide II, Atractylenolide III, and Atractyloside A in Rat Plasma after Oral Administration of Raw and Wheat Bran-Processed Atractylodis Rhizoma

(2018) Shizhao Xu et al.   MOLECULES

Atractylenolide II Induces Apoptosis of Prostate Cancer Cells through Regulation of AR and JAK2/STAT3 Signaling Pathways

(2018) Jing Wang et al.   MOLECULES

Bojungikgi-Tang, a Traditional Herbal Formula, Exerts Neuroprotective Effects and Ameliorates Memory Impairments in Alzheimer’s Disease-Like Experimental Models

(2018) Hye-Sun Lim et al.   Nutrients

Pharmacological effects of medicinal components of Atractylodes lancea (Thunb.) DC.

(2018) Xie Jun et al.   Chinese Medicine

Atractylenolide I restores HO-1 expression and inhibits Ox-LDL-induced VSMCs proliferation, migration and inflammatory responses in vitro

(2017) Weifeng Li et al.   EXPERIMENTAL CELL RESEARCH

Ameliorative effect of atractylenolide III in the mast cell proliferation induced by TSLP

(2017) Myoung-schook Yoou et al.   FOOD AND CHEMICAL TOXICOLOGY

Complementary Chinese Herbal Medicine Therapy Improves Survival of Patients With Pancreatic Cancer in Taiwan: A Nationwide Population-Based Cohort Study

(2017) Yi-Ting Kuo et al.   INTEGRATIVE CANCER THERAPIES

Comparison of byakujutsu (Atractylodes rhizome) and sojutsu (Atractylodes lancea rhizome) on anti-inflammatory and immunostimulative effects in vitro

(2017) Yohta Shimato et al.   Journal of Natural Medicines

Influence of sulfur fumigation on the chemical profiles of Atractylodes macrocephala Koidz. evaluated by UFLC–QTOF–MS combined with multivariate statistical analysis

(2017) Xue Sun et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Antitumor activity of 2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-cyclohexadiene-1,4-dione isolated from the aerial part of Atractylodes macrocephala in hepatocellular carcinoma

(2017) Lei Li et al.   Molecular Medicine Reports

Identification of a Multicomponent Traditional Herbal Medicine by HPLC–MS and Electron and Light Microscopy

(2017) Ju-Han Liu et al.   MOLECULES

Using UPLC-MS/MS for Characterization of Active Components in Extracts of Yupingfeng and Application to a Comparative Pharmacokinetic Study in Rat Plasma after Oral Administration

(2017) Meng-Qi Jia et al.   MOLECULES

Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS

(2017) Shuang Tian et al.   MOLECULES

Neuroprotective Role of Atractylenolide-I in an In Vitro and In Vivo Model of Parkinson’s Disease

(2017) et al.   Nutrients

Chemopreventive effects of atractylenolide II on mammary tumorigenesis via activating Nrf2-ARE pathway

(2017) Ting Wang et al.   Oncotarget

Anti-Tumor Effects of Atractylenolide-I on Human Ovarian Cancer Cells

(2017) Fangyi Long et al.   MEDICAL SCIENCE MONITOR

Targeting PDK1 for Chemosensitization of Cancer Cells

(2017) Aikaterini Emmanouilidi et al.   Cancers

Regionalization of Chinese Material Medical Quality Based on Maximum Entropy Model: A case study of Atractylodes lancea

(2017) Zhu Shoudong et al.   Scientific Reports

Induction of apoptosis and differentiation by atractylenolide-1 isolated from Atractylodes macrocephala in human leukemia cells

(2016) Huey-Lan Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inflammatory Inhibitory Activity of Sesquiterpenoids from Atractylodes macrocephala Rhizomes

(2016) Le Son Hoang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Sesquiterpenoids from the seeds of Sarcandra glabra and the potential anti-inflammatory effects

(2016) Saimijiang Yaermaimaiti et al.   FITOTERAPIA

Anti-inflammatory and Antinociceptive Constituents of Atractylodes japonica Koidzumi

(2016) Lih-Geeng Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Two new compounds from Atractylodes macrocephala with neuroprotective activity

(2016) Na Zhang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

The combination effects of Shen-Ling-Bai-Zhu on promoting apoptosis of transplanted H22 hepatocellular carcinoma in mice receiving chemotherapy

(2016) Shengyan Xi et al.   JOURNAL OF ETHNOPHARMACOLOGY

A systems pharmacology approach to decipher the mechanism of danggui-shaoyao-san decoction for the treatment of neurodegenerative diseases

(2016) Yunxia Luo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-tumor effects of Atractylenolide I on bladder cancer cells

(2016) Rui Yu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Classification of the medicinal plants of the genusAtractylodesusing high-performance liquid chromatography with diode array and tandem mass spectrometry detection combined with multivariate statistical analysis

(2016) Hyun-Deok Cho et al.   JOURNAL OF SEPARATION SCIENCE

Atractylenolide I modulates ovarian cancer cell-mediated immunosuppression by blocking MD-2/TLR4 complex-mediated MyD88/NF-κB signaling in vitro

(2016) Hong Liu et al.   Journal of Translational Medicine

Atractylodes lactone compounds inhibit platelet activation

(2016) Yizhu Chen et al.   PLATELETS

Insecticidal and Repellant Activities of Polyacetylenes and Lactones Derived fromAtractylodes lanceaRhizomes

(2015) Hai-Ping Chen et al.   CHEMISTRY & BIODIVERSITY

Atractylenolide I protects mice from lipopolysaccharide-induced acute lung injury

(2015) Jun-liang Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory activity of atractylenolide III through inhibition of nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophages

(2015) Guang-Quan Ji et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Assessment of the embryotoxicity of four Chinese herbal extracts using the embryonic stem cell test

(2015) LIN-YAN LI et al.   Molecular Medicine Reports

Neuroprotection and mechanisms of atractylenolide III in preventing learning and memory impairment induced by chronic high-dose homocysteine administration in rats

(2015) H. Zhao et al.   NEUROSCIENCE

ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells

(2015) YAN YE et al.   ONCOLOGY REPORTS

The natural compound codonolactone attenuates TGF-β1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells

(2015) JIANJIANG FU et al.   ONCOLOGY REPORTS

1β-Hydroxyalantolactone, a sesquiterpene lactone fromInula japonica, attenuates atopic dermatitis-like skin lesions induced by 2,4-dinitrochlorobenzene in the mouse

(2015) Guochao Lin et al.   PHARMACEUTICAL BIOLOGY

The protective effect of atractylenolide I on systemic inflammation in the mouse model of sepsis created by cecal ligation and puncture

(2015) Aimin Wang et al.   PHARMACEUTICAL BIOLOGY

The natural compound codonolactone impairs tumor induced angiogenesis by downregulating BMP signaling in endothelial cells

(2015) Shan Wang et al.   PHYTOMEDICINE

Strong Specific Inhibition of UDP-glucuronosyltransferase 2B7 by Atractylenolide I and III

(2015) Qian Zhang et al.   PHYTOTHERAPY RESEARCH

A general, concise, ‘collective’ approach to eudesmanolide sesquiterpenoids: total synthesis of bioactive atractylenolides I–IV and related natural products

(2015) Subburethinam Ramesh et al.   TETRAHEDRON LETTERS

Mechanisms and pathways of innate immune activation and regulation in health and cancer

(2015) Jun Cui et al.   Human Vaccines & Immunotherapeutics

Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits

(2014) Li Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II

(2014) Xiu-Qiong Fu et al.   EXPERIMENTAL DERMATOLOGY

Codonolactone, a sesquiterpene lactone isolated from Chloranthus henryi Hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of Runx2

(2014) WEI WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A Simultaneous Determination of Principal Compounds in Tokishakuyakusan by High-Performance Liquid Chromatography with Diode Array Detector

(2014) M. Sumino et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Identification and pharmacokinetics of multiple constituents in rat plasma after oral administration of Yinchenzhufu decoction

(2014) Qian Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacological Effects of “Jutsu” (Atractylodis rhizome and Atractylodis lanceae rhizome) on 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-Induced Head Twitch Response in Mice (I)

(2014) Chiaki Murayama et al.   MOLECULES

Neuroprotection of Atractylenolide III from Atractylodis macrocephalae Against Glutamate-Induced Neuronal Apoptosis Via Inhibiting Caspase Signaling Pathway

(2014) Chao Liu et al.   NEUROCHEMICAL RESEARCH

Simultaneous determination of 11 bioactive compounds in Jaeumganghwa-tang by high performance liquid chromatography-diode array detection

(2014) ChoongJe Ma et al.   Pharmacognosy Magazine

Chromatographic fingerprinting analysis of Zhizhu Wan preparation by high-performance liquid chromatography coupled with photodiode array detector

(2014) Xijun Wang et al.   Pharmacognosy Magazine

Dang Shen[Codonopsis pilosula(Franch.) Nannf] Herbal Formulae for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis

(2014) Johannah L. Shergis et al.   PHYTOTHERAPY RESEARCH

Atractylenolide-I Sensitizes Human Ovarian Cancer Cells to Paclitaxel by Blocking Activation of TLR4/MyD88-dependent Pathway

(2014) Jian-Ming Huang et al.   Scientific Reports

Pharmacokinetic–pharmacodynamic evaluation of the major component astragaloside IV on the immunomodulatory effects of Yu-ping-feng prescription

(2013) Jue Song et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

UPLC–Q-TOF-MS/MS fingerprinting of Traditional Chinese Formula SiJunZiTang

(2013) Yanyan Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Content determination of the major constituents of Yinchenzhufu decoction via ultra high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry

(2013) Qian Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Anti-Tumor Effects of Atractylenolide I Isolated from Atractylodes macrocephala in Human Lung Carcinoma Cell Lines

(2013) Huanyi Liu et al.   MOLECULES

Targeting of the Sonic Hedgehog Pathway by Atractylenolides Promotes Chondrogenic Differentiation of Mesenchymal Stem Cells

(2012) Xican Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Simultaneous determination of atractylenolide II and atractylenolide III by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of Atractylodes Macrocephala Rhizoma extract

(2012) Yang-yang Shi et al.   BIOMEDICAL CHROMATOGRAPHY

Identification and quantification of the major volatile constituents in antidepressant active fraction of xiaoyaosan by gas chromatography–mass spectrometry

(2012) Yuzhi Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

The inhibitory activity of atractylenolide Ш, a sesquiterpenoid, on IgE-mediated mast cell activation and passive cutaneous anaphylaxis (PCA)

(2012) Nan-nan Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Molecular studies of the congenital malformation induced by Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage

(2012) L. Y. Tang et al.   MOLECULAR HUMAN REPRODUCTION

A new sesquiterpene lactone fromSarcandra glabra

(2012) Xiao-Ru Hu et al.   NATURAL PRODUCT RESEARCH

Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage

(2011) L. Li et al.   HUMAN REPRODUCTION

Blockade of IL-6 Secretion Pathway by the Sesquiterpenoid Atractylenolide III

(2011) Tae-Hee Kang et al.   JOURNAL OF NATURAL PRODUCTS

Quantitative analysis of atractylenolide I in rat plasma by LC–MS/MS method and its application to pharmacokinetic study

(2011) Yujuan Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Screening for Compounds with Aromatase Inhibiting Activities from Atractylodes macrocephala Koidz

(2011) Hai Jiang et al.   MOLECULES

Atractylodes japonica Koidzumi inhibits the production of proinflammatory cytokines through inhibition of the NF-κB/IκB signal pathway in HMC-1 human mast cells

(2010) Myung Hee Hong et al.   ARCHIVES OF PHARMACAL RESEARCH

Effects of Sesquiterpenes Isolated From Largehead Atractylodes Rhizome on Growth, Migration, and Differentiation of B16 Melanoma Cells

(2010) Yan Ye et al.   INTEGRATIVE CANCER THERAPIES

Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro

(2009) Changhe Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sesquiterpene Lactones from the Root Tubers ofLindera aggregata

(2009) Li-She Gan et al.   JOURNAL OF NATURAL PRODUCTS

A new cytotoxic prenylated dihydrobenzofuran derivative and other chemical constituents from the rhizomes of Atractylodes lancea DC

(2008) Jin-ao Duan et al.   ARCHIVES OF PHARMACAL RESEARCH

Two new sesquiterpene lactones fromSarcandra glabra

(2008) Li-Ping Zhu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

A capillary gas chromatography-selected ion monitoring mass spectrometry method for the analysis of atractylenolide I in rat plasma and tissues, and application in a pharmacokinetic study

(2008) Changhe Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A Randomized Pilot Study of Atractylenolide I on Gastric Cancer Cachexia Patients

(2007) Yi Liu et al.   Evidence-based Complementary and Alternative Medicine