Modulation of phagosome phosphoinositide dynamics by a Legionella phosphoinositide 3‐kinase

Phosphoinositides and the Fate of Legionella in Phagocytes

(2020) A. Leoni Swart et al.   Frontiers in Immunology

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

(2019) Laura Gomez-Valero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Study of Legionella Effector Domains Revealed Novel and Prevalent Phosphatidylinositol 3-Phosphate Binding Domains

(2019) Nimrod Nachmias et al.   INFECTION AND IMMUNITY

Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases

(2019) Miles H. Black et al.   SCIENCE

Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase

(2019) Ninghai Gan et al.   NATURE

Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation

(2019) Sagar Bhogaraju et al.   NATURE

Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen

(2019) Edwin E. Jeng et al.   Cell Host & Microbe

Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB

(2019) Donghyuk Shin et al.   MOLECULAR CELL

Deubiquitination of phosphoribosyl-ubiquitin conjugates by phosphodiesterase-domain–containing Legionella effectors

(2019) Min Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ

(2019) Alan Sulpizio et al.   eLife

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

(2018) Benjamin Kleaveland et al.   CELL

A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella

(2018) Hannah E. Ledvina et al.   Cell Host & Microbe

Legionella-Containing Vacuoles Capture PtdIns(4)P-Rich Vesicles Derived from the Golgi Apparatus

(2018) Stephen Weber et al.   mBio

Legionella and Coxiella effectors: strength in diversity and activity

(2017) Jiazhang Qiu et al.   NATURE REVIEWS MICROBIOLOGY

Formation of the Legionella Replicative Compartment at the Crossroads of Retrograde Trafficking

(2017) Kevin Bärlocher et al.   Frontiers in Cellular and Infection Microbiology

Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination

(2016) Sagar Bhogaraju et al.   CELL

Phosphatidylinositol 3‐phosphates—at the interface between cell signalling and membrane traffic

(2016) Andrea L Marat et al.   EMBO JOURNAL

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

(2016) Malene L Urbanus et al.   Molecular Systems Biology

Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

(2016) Jiazhang Qiu et al.   NATURE

Subversion of Retrograde Trafficking by Translocated Pathogen Effectors

(2016) Nicolas Personnic et al.   TRENDS IN MICROBIOLOGY

Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector

(2016) Na Dong et al.   Nature Microbiology

Novel Type III Effectors in Pseudomonas aeruginosa

(2015) David Burstein et al.   mBio

Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5

(2014) M. Lucas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

(2014) Andree Hubber et al.   PLoS Pathogens

The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication

(2013) Ivo Finsel et al.   Cell Host & Microbe

Identification of Legionella pneumophila Effectors Regulated by the LetAS-RsmYZ-CsrA Regulatory Cascade, Many of Which Modulate Vesicular Trafficking

(2013) O. Nevo et al.   JOURNAL OF BACTERIOLOGY

Identification and Structural Characterization of aLegionellaPhosphoinositide Phosphatase

(2013) Leila Toulabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection

(2013) Eva Rothmeier et al.   PLoS Pathogens

Phosphoinositides and vesicular membrane traffic

(2012) Peter Mayinger   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Legionella pneumophila Effector DrrA Is Sufficient to Stimulate SNARE-Dependent Membrane Fusion

(2012) Kohei Arasaki et al.   Cell Host & Microbe

Domain organization of Legionella effector SetA

(2012) Thomas Jank et al.   CELLULAR MICROBIOLOGY

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase

(2012) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploitation of evolutionarily conserved amoeba and mammalian processes by Legionella

(2012) Tasneem Al-Quadan et al.   TRENDS IN MICROBIOLOGY

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

The E Block motif is associated with Legionella pneumophila translocated substrates

(2010) Li Huang et al.   CELLULAR MICROBIOLOGY

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

Coordination of Golgi functions by phosphatidylinositol 4-kinases

(2010) Todd R. Graham et al.   TRENDS IN CELL BIOLOGY

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequential Actions of Myotubularin Lipid Phosphatases Regulate Endosomal PI(3)P and Growth Factor Receptor Trafficking

(2008) Canhong Cao et al.   MOLECULAR BIOLOGY OF THE CELL

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY