Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors

Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling

(2015) Shufeng Zhou et al.   DEVELOPMENT

Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation

(2015) Jianmin Zhang et al.   DEVELOPMENTAL BIOLOGY

Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish

(2014) I A Viringipurampeer et al.   CELL DEATH AND DIFFERENTIATION

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Number and Distribution of Mouse Retinal Cone Photoreceptors: Differences between an Albino (Swiss) and a Pigmented (C57/BL6) Strain

(2014) Arturo Ortín-Martínez et al.   PLoS One

The Electroretinogram as a Biomarker of Central Dopamine and Serotonin: Potential Relevance to Psychiatric Disorders

(2013) Joëlle Lavoie et al.   BIOLOGICAL PSYCHIATRY

Developmentally Regulated Linker Histone H1c Promotes Heterochromatin Condensation and Mediates Structural Integrity of Rod Photoreceptors in Mouse Retina

(2013) Evgenya Y. Popova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription Coactivators p300 and CBP Are Necessary for Photoreceptor-Specific Chromatin Organization and Gene Expression

(2013) Anne K. Hennig et al.   PLoS One

Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins

(2013) D. Zencak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G9a Histone Methyltransferase Activity in Retinal Progenitors Is Essential for Proper Differentiation and Survival of Mouse Retinal Cells

(2012) K. Katoh et al.   JOURNAL OF NEUROSCIENCE

Bmi1 Is Down-Regulated in the Aging Brain and Displays Antioxidant and Protective Activities in Neurons

(2012) Mohamed Abdouh et al.   PLoS One

Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration

(2012) Y. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

(2012) Kimberly Larson et al.   PLoS Genetics

DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs

(2011) Mohammad M. Karimi et al.   Cell Stem Cell

The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity

(2011) F. Kappes et al.   GENES & DEVELOPMENT

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

An anticlastogenic function for the Polycomb Group gene Bmi1

(2011) J. Chagraoui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Su(var) Genes in Chromatin Control

(2010) Barna D. Fodor et al.   Annual Review of Cell and Developmental Biology

p53 Pro-Oxidant Activity in the Central Nervous System: Implication in Aging and Neurodegenerative Diseases

(2010) Wassim Chatoo et al.   ANTIOXIDANTS & REDOX SIGNALING

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

(2010) Srividya Bhaskara et al.   CANCER CELL

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

(2010) Martin Sauvageau et al.   Cell Stem Cell

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

(2010) Ismail Hassan Ismail et al.   JOURNAL OF CELL BIOLOGY

BMI1 Confers Radioresistance to Normal and Cancerous Neural Stem Cells through Recruitment of the DNA Damage Response Machinery

(2010) S. Facchino et al.   JOURNAL OF NEUROSCIENCE

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina

(2010) Anand Swaroop et al.   NATURE REVIEWS NEUROSCIENCE

Bmi1 Distinguishes Immature Retinal Progenitor/Stem Cells from the Main Progenitor Cell Population and Is Required for Normal Retinal Development

(2010) Wassim Chatoo et al.   STEM CELLS

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

The Polycomb Group Gene Bmi1 Regulates Antioxidant Defenses in Neurons by Repressing p53 Pro-Oxidant Activity

(2009) W. Chatoo et al.   JOURNAL OF NEUROSCIENCE

BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal

(2009) M. Abdouh et al.   JOURNAL OF NEUROSCIENCE

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

Retinoid-related orphan nuclear receptor ROR  is an early-acting factor in rod photoreceptor development

(2009) L. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene

(2009) B. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation

(2009) Jamy C. Peng et al.   PLoS Genetics

Photoreceptor Cell Death Mechanisms in Inherited Retinal Degeneration

(2008) Javier Sancho-Pelluz et al.   MOLECULAR NEUROBIOLOGY