Development of intestinal organoids as tissue surrogates: Cell composition and the Epigenetic control of differentiation

Intestinal organoids as tissue surrogates for toxicological and pharmacological studies

(2013) Anton Kuratnik et al.   BIOCHEMICAL PHARMACOLOGY

Tropolones As Lead-Like Natural Products: The Development of Potent and Selective Histone Deacetylase Inhibitors

(2013) Sophia N. Ononye et al.   ACS Medicinal Chemistry Letters

CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice

(2012) Jeffrey B. King et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

(2012) Javier Muñoz et al.   EMBO JOURNAL

Dclk1 distinguishes between tumor and normal stem cells in the intestine

(2012) Yuki Nakanishi et al.   NATURE GENETICS

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell

(2012) Shiro Yui et al.   NATURE MEDICINE

Paneth Cells in Intestinal Homeostasis and Tissue Injury

(2012) Sabrina Roth et al.   PLoS One

Role of Notch signaling in colon homeostasis and carcinogenesis

(2011) Shingo Miyamoto et al.   CANCER SCIENCE

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium

(2011) François Gerbe et al.   JOURNAL OF CELL BIOLOGY

Microenvironmental regulation of stem cells in intestinal homeostasis and cancer

(2011) Jan Paul Medema et al.   NATURE

Single-molecule transcript counting of stem-cell markers in the mouse intestine

(2011) Shalev Itzkovitz et al.   NATURE CELL BIOLOGY

Isolation and in vitro expansion of human colonic stem cells

(2011) Peter Jung et al.   NATURE MEDICINE

Generating human intestinal tissue from pluripotent stem cells in vitro

(2011) Kyle W McCracken et al.   Nature Protocols

Interconversion Between Intestinal Stem Cell Populations in Distinct Niches

(2011) N. Takeda et al.   SCIENCE

Altered Dynamics of Intestinal Cell Maturation in Apc1638N/+ Mice

(2010) D. Wang et al.   CANCER RESEARCH

Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate

(2010) Kelli L. VanDussen et al.   DEVELOPMENTAL BIOLOGY

Intestinal lineage commitment of embryonic stem cells

(2010) Li Cao et al.   DIFFERENTIATION

EGF signaling activates proliferation and blocks apoptosis of mouse and human intestinal stem/progenitor cells in long-term monolayer cell culture

(2010) Atsushi Suzuki et al.   LABORATORY INVESTIGATION

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells

(2010) R. K. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The expression and crucial roles of BMP signaling in development of smooth muscle progenitor cells in the mouse embryonic gut

(2009) Shigeko Torihashi et al.   DIFFERENTIATION

DCAMKL-1 Expression Identifies Tuft Cells Rather Than Stem Cells in the Adult Mouse Intestinal Epithelium

(2009) François Gerbe et al.   GASTROENTEROLOGY

Single-cell transcript analysis of human embryonic stem cells

(2009) Jason D. Gibson et al.   Integrative Biology

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

(2009) Akifumi Ootani et al.   NATURE MEDICINE

Doublecortin and CaM Kinase-like-1 and Leucine-Rich-Repeat-Containing G-Protein-Coupled Receptor Mark Quiescent and Cycling Intestinal Stem Cells, Respectively

(2009) Randal May et al.   STEM CELLS

Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interactions with myofibroblasts

(2008) S. Samuel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells

(2008) D. T. Breault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Novel Putative Gastrointestinal Stem Cell and Adenoma Stem Cell Marker, Doublecortin and CaM Kinase-Like-1, Following Radiation Injury and in Adenomatous Polyposis Coli/Multiple Intestinal Neoplasia Mice

(2007) Randal May et al.   STEM CELLS