Cloning and variation of ground state intestinal stem cells

GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development

(2014) Emily M. Walker et al.   DEVELOPMENTAL BIOLOGY

DUOX2 and DUOXA2 Form the Predominant Enzyme System Capable of Producing the Reactive Oxygen Species H2O2 in Active Ulcerative Colitis and are Modulated by 5-Aminosalicylic Acid

(2014) Tammie S. MacFie et al.   INFLAMMATORY BOWEL DISEASES

An in vivo model of human small intestine using pluripotent stem cells

(2014) Carey L Watson et al.   NATURE MEDICINE

Pluripotent stem cells in regenerative medicine: challenges and recent progress

(2014) Viviane Tabar et al.   NATURE REVIEWS GENETICS

Adult Stem Cells in the Small Intestine Are Intrinsically Programmed with Their Location-Specific Function

(2014) Sabine Middendorp et al.   STEM CELLS

iPS cell technologies: significance and applications to CNS regeneration and disease

(2014) Hideyuki Okano et al.   Molecular Brain

Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury

(2013) Robert P. Fordham et al.   Cell Stem Cell

Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration

(2013) Ciara Metcalfe et al.   Cell Stem Cell

Isolation and Characterization of Intestinal Stem Cells Based on Surface Marker Combinations and Colony-Formation Assay

(2013) Fengchao Wang et al.   GASTROENTEROLOGY

Generation of Engraftable Hematopoietic Stem Cells From Induced Pluripotent Stem Cells by Way of Teratoma Formation

(2013) Nao Suzuki et al.   MOLECULAR THERAPY

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny

(2013) Xiaolei Yin et al.   NATURE METHODS

Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex

(2013) M. A. Farrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BCL-XL Mediates the Strong Selective Advantage of a 20q11.21 Amplification Commonly Found in Human Embryonic Stem Cell Cultures

(2013) Stuart Avery et al.   Stem Cell Reports

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

(2012) G. Amabile et al.   BLOOD

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

(2012) Anne E. Powell et al.   CELL

Creating diseases to understand what prevents them: genetic analysis of inflammation in the gastrointestinal tract

(2012) Katharina Brandl et al.   CURRENT OPINION IN IMMUNOLOGY

Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell

(2012) Shiro Yui et al.   NATURE MEDICINE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Transcriptional Networks in Liver and Intestinal Development

(2012) K. L. Sheaffer et al.   Cold Spring Harbor Perspectives in Biology

Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism

(2012) Nicole M. Chumbler et al.   PLoS Pathogens

Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

(2011) Pooja A. Kumar et al.   CELL

New IBD genetics: common pathways with other diseases

(2011) C. W. Lees et al.   GUT

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

(2011)   NATURE BIOTECHNOLOGY

The role of toxin A and toxin B in the virulence of Clostridium difficile

(2011) Glen P. Carter et al.   TRENDS IN MICROBIOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration

(2010) Paolo Rama et al.   NEW ENGLAND JOURNAL OF MEDICINE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Onecut-2 knockout mice fail to thrive during early postnatal period and have altered patterns of gene expression in small intestine

(2010) Mary R. Dusing et al.   PHYSIOLOGICAL GENOMICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

(2009) Akifumi Ootani et al.   NATURE MEDICINE

GATA4 Is Essential for Jejunal Function in Mice

(2008) Michele A. Battle et al.   GASTROENTEROLOGY

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

(2008) Liqin Zhu et al.   NATURE

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

HOXB4 But Not BMP4 Confers Self-Renewal Properties to ES-Derived Hematopoietic Progenitor Cells

(2008) Sabrina Bonde et al.   TRANSPLANTATION