Actin-Membrane Release Initiates Cell Protrusions

Of Cell Shapes and Motion: The Physical Basis of Animal Cell Migration

(2020) Dani L. Bodor et al.   DEVELOPMENTAL CELL

Ezrin, a prognostic indicator, regulates colon adenocarcinoma progression through glycolysis

(2020) Yixuan Wang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Filament flexibility enhances power transduction of F-actin bundles

(2019) Alessia Perilli et al.   JOURNAL OF CHEMICAL PHYSICS

Nuclear positioning facilitates amoeboid migration along the path of least resistance

(2019) Jörg Renkawitz et al.   NATURE

Branch-restricted localization of phosphatase Prl-1 specifies axonal synaptogenesis domains

(2019) Olivier Urwyler et al.   SCIENCE

Plastic Deformation and Fragmentation of Strained Actin Filaments

(2019) Anthony C. Schramm et al.   BIOPHYSICAL JOURNAL

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

(2019) Mihai L. Azoitei et al.   JOURNAL OF CELL BIOLOGY

Robust and automated detection of subcellular morphological motifs in 3D microscopy images

(2019) Meghan K. Driscoll et al.   NATURE METHODS

Plasticity of cell migration resulting from mechanochemical coupling

(2019) Yuansheng Cao et al.   eLife

The actin cortex at a glance

(2018) Priyamvada Chugh et al.   JOURNAL OF CELL SCIENCE

Rheology of Membrane-Attached Minimal Actin Cortices

(2018) Helen Nöding et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Myosin II–interacting guanine nucleotide exchange factor promotes bleb retraction via stimulating cortex reassembly at the bleb membrane

(2018) Meng Jiao et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of ezrin expression reduced the susceptibility to the glomerular injury in mice

(2018) Ryo Hatano et al.   Scientific Reports

Profiling cellular morphodynamics by spatiotemporal spectrum decomposition

(2018) Xiao Ma et al.   PLoS Computational Biology

Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

(2018) Feng-Ching Tsai et al.   eLife

Dissecting the actin cortex density and membrane-cortex distance in living cells by super-resolution microscopy

(2017) M P Clausen et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Diagonally Scanned Light-Sheet Microscopy for Fast Volumetric Imaging of Adherent Cells

(2016) Kevin M. Dean et al.   BIOPHYSICAL JOURNAL

Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments

(2016) Erik S. Welf et al.   DEVELOPMENTAL CELL

Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy

(2015) Kevin M. Dean et al.   BIOPHYSICAL JOURNAL

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Actin Flows Mediate a Universal Coupling between Cell Speed and Cell Persistence

(2015) Paolo Maiuri et al.   CELL

ERK reinforces actin polymerization to power persistent edge protrusion during motility

(2015) Michelle C. Mendoza et al.   Science Signaling

ERK reinforces actin polymerization to power persistent edge protrusion during motility

(2015) Michelle C. Mendoza et al.   Science Signaling

Functional Hierarchy of Redundant Actin Assembly Factors Revealed by Fine-Grained Registration of Intrinsic Image Fluctuations

(2015) Kwonmoo Lee et al.   Cell Systems

Physical Model for the Geometry of Actin-Based Cellular Protrusions

(2014) G. Orly et al.   BIOPHYSICAL JOURNAL

Quantitative Analysis of Ezrin Turnover Dynamics in the Actin Cortex

(2014) Marco Fritzsche et al.   BIOPHYSICAL JOURNAL

Phosphatidylinositol 4,5-Bisphosphate Alters the Number of Attachment Sites between Ezrin and Actin Filaments

(2014) Julia A. Braunger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ezrin Mediates Neuritogenesis via Down-Regulation of RhoA Activity in Cultured Cortical Neurons

(2014) Yosuke Matsumoto et al.   PLoS One

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility

(2013) Erik S. Welf et al.   MOLECULAR BIOLOGY OF THE CELL

Excitable Actin Dynamics in Lamellipodial Protrusion and Retraction

(2012) Gillian L. Ryan et al.   BIOPHYSICAL JOURNAL

Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

(2012) Erik S. Welf et al.   JOURNAL OF CELL BIOLOGY

Coupling actin flow, adhesion, and morphology in a computational cell motility model

(2012) D. Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic control of phosphoinositide metabolism

(2012) O. Idevall-Hagren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell mechanics control rapid transitions between blebs and lamellipodia during migration

(2012) M. Bergert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesoscopic Model of Actin-Based Propulsion

(2012) Jie Zhu et al.   PLoS Computational Biology

Activation of F-Actin Binding Capacity of Ezrin: Synergism of PIP2 Interaction and Phosphorylation

(2011) Sabine Bosk et al.   BIOPHYSICAL JOURNAL

An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells

(2011) A. Lorentzen et al.   JOURNAL OF CELL SCIENCE

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells

(2011) G Bulut et al.   ONCOGENE

Chemotaxis: A Feedback-Based Computational Model Robustly Predicts Multiple Aspects of Real Cell Behaviour

(2011) Matthew P. Neilson et al.   PLOS BIOLOGY

Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

(2009) Jian-Jiang Hao et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Mechanism of shape determination in motile cells

(2008) Kinneret Keren et al.   NATURE

Fluctuations of intracellular forces during cell protrusion

(2008) Lin Ji et al.   NATURE CELL BIOLOGY

Ezrin is a specific and direct target of protein tyrosine phosphatase PRL-3

(2007) Eleonora Forte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH