Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility
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Title
Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility
Authors
Keywords
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Journal
MOLECULAR BIOLOGY OF THE CELL
Volume 24, Issue 24, Pages 3945-3955
Publisher
American Society for Cell Biology (ASCB)
Online
2013-10-24
DOI
10.1091/mbc.e13-06-0311
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Note: Only part of the references are listed.- Two modes of integrin activation form a binary molecular switch in adhesion maturation
- (2013) Ho-Sup Lee et al. MOLECULAR BIOLOGY OF THE CELL
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- (2012) Feng-Chiao Tsai et al. CURRENT BIOLOGY
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- Quantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer
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- -Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration
- (2012) Z. B. Katz et al. GENES & DEVELOPMENT
- Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism
- (2012) Erik S. Welf et al. JOURNAL OF CELL BIOLOGY
- United we stand – integrating the actin cytoskeleton and cell–matrix adhesions in cellular mechanotransduction
- (2012) Ulrich S. Schwarz et al. JOURNAL OF CELL SCIENCE
- Coupling actin flow, adhesion, and morphology in a computational cell motility model
- (2012) D. Shao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- How Cells Integrate Complex Stimuli: The Effect of Feedback from Phosphoinositides and Cell Shape on Cell Polarization and Motility
- (2012) Athanasius F. M. Marée et al. PLoS Computational Biology
- Biochemical and mechanical extracellular matrix properties dictate mammary epithelial cell motility and assembly
- (2011) Olga Shebanova et al. Biotechnology Journal
- Computer Vision in Cell Biology
- (2011) Gaudenz Danuser CELL
- Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
- (2011) Violaine D. Delorme-Walker et al. JOURNAL OF CELL BIOLOGY
- Actomyosin-generated tension controls the molecular kinetics of focal adhesions
- (2011) H. Wolfenson et al. JOURNAL OF CELL SCIENCE
- How does the antagonism between capping and anti-capping proteins affect actin network dynamics?
- (2011) Longhua Hu et al. JOURNAL OF PHYSICS-CONDENSED MATTER
- A role for actin arcs in the leading-edge advance of migrating cells
- (2011) Dylan T. Burnette et al. NATURE CELL BIOLOGY
- The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
- (2011) Christophe Guilluy et al. NATURE CELL BIOLOGY
- Integrins in Cell Migration
- (2011) A. Huttenlocher et al. Cold Spring Harbor Perspectives in Biology
- An Adhesion-Dependent Switch between Mechanisms That Determine Motile Cell Shape
- (2011) Erin L. Barnhart et al. PLOS BIOLOGY
- Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration
- (2010) Margaret L. Gardel et al. Annual Review of Cell and Developmental Biology
- Modeling of Protrusion Phenotypes Driven by the Actin-Membrane Interaction
- (2010) Mihaela Enculescu et al. BIOPHYSICAL JOURNAL
- Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating Cells
- (2010) Erik S. Welf et al. Cellular and Molecular Bioengineering
- Transient Frictional Slip between Integrin and the ECM in Focal Adhesions under Myosin II Tension
- (2010) Yvonne Aratyn-Schaus et al. CURRENT BIOLOGY
- Protrusion and actin assembly are coupled to the organization of lamellar contractile structures
- (2010) James I. Lim et al. EXPERIMENTAL CELL RESEARCH
- Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
- (2010) Carsten Grashoff et al. NATURE
- Cell adhesion: integrating cytoskeletal dynamics and cellular tension
- (2010) J. Thomas Parsons et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Leading-edge–gel coupling in lamellipodium motion
- (2010) Juliane Zimmermann et al. PHYSICAL REVIEW E
- Cells navigate with a local-excitation, global-inhibition-biased excitable network
- (2010) Y. Xiong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells
- (2010) Sam Walcott et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Signaling pathways that control cell migration: models and analysis
- (2010) Erik S. Welf et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Kinetic model for lamellipodal actin-integrin 'clutch' dynamics
- (2010) Alice Macdonald et al. Cell Adhesion & Migration
- Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells
- (2010) Murat Cirit et al. PLoS Computational Biology
- An Open Model of Actin Dendritic Nucleation
- (2009) Jonathon A. Ditlev et al. BIOPHYSICAL JOURNAL
- Actin-Myosin Viscoelastic Flow in the Keratocyte Lamellipod
- (2009) Boris Rubinstein et al. BIOPHYSICAL JOURNAL
- Integrins in cell migration - the actin connection
- (2009) M. Vicente-Manzanares et al. JOURNAL OF CELL SCIENCE
- Coordination of Rho GTPase activities during cell protrusion
- (2009) Matthias Machacek et al. NATURE
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- (2009) Miguel Vicente-Manzanares et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Neutrophils display biphasic relationship between migration and substrate stiffness
- (2009) Kimberly M. Stroka et al. CELL MOTILITY AND THE CYTOSKELETON
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- (2009) Matthew J. Paszek et al. PLoS Computational Biology
- Exploring the Control Circuit of Cell Migration by Mathematical Modeling
- (2008) Javier Satulovsky et al. BIOPHYSICAL JOURNAL
- Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed
- (2008) Margaret L. Gardel et al. JOURNAL OF CELL BIOLOGY
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- Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner
- (2008) Colin K. Choi et al. NATURE CELL BIOLOGY
- Fluctuations of intracellular forces during cell protrusion
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- Comparative Dynamics of Retrograde Actin Flow and Focal Adhesions: Formation of Nascent Adhesions Triggers Transition from Fast to Slow Flow
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- Traction Dynamics of Filopodia on Compliant Substrates
- (2008) C. E. Chan et al. SCIENCE
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