Origin of translational control by eIF2α phosphorylation: insights from genome-wide translational profiling studies in fission yeast

eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide

(2020) Fujun Zhou et al.   RNA

Gcn2 eIF2α kinase mediates combinatorial translational regulation through nucleotide motifs and uORFs in target mRNAs

(2020) Yuji Chikashige et al.   NUCLEIC ACIDS RESEARCH

Unusually efficient CUG initiation of an overlapping reading frame in POLG mRNA yields novel protein POLGARF

(2020) Gary Loughran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introns are mediators of cell response to starvation

(2019) Julie Parenteau et al.   NATURE

Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancer

(2019) Kuniaki Sato et al.   EBioMedicine

Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design

(2019) Pierce J. Ogden et al.   SCIENCE

General amino acid control in fission yeast is regulated by a nonconserved transcription factor, with functions analogous to Gcn4/Atf4

(2018) Caia D. S. Duncan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-AUG translation: a new start for protein synthesis in eukaryotes

(2017) Michael G. Kearse et al.   GENES & DEVELOPMENT

Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability

(2017) Amandine Bonnet et al.   MOLECULAR CELL

Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide

(2017) Leiming Tang et al.   NUCLEIC ACIDS RESEARCH

Activation of Gcn2 in response to different stresses

(2017) Silje Anda et al.   PLoS One

Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response

(2016) Sara K. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and inducesATF4translation through delayed re-initiation

(2016) Caitlin Kozel et al.   NUCLEIC ACIDS RESEARCH

Comparative genomics of biotechnologically important yeasts

(2016) Robert Riley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Ancient Yeast for Young Geneticists: A Primer on theSchizosaccharomyces pombeModel System

(2015) Charles S. Hoffman et al.   GENETICS

Ribosome Reinitiation Directs Gene-specific Translation and Regulates the Integrated Stress Response

(2015) Sara K. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase

(2015) Meng S. Choy et al.   Cell Reports

An Ancient Yeast for Young Geneticists: A Primer on theSchizosaccharomyces pombeModel System

(2015) Charles S. Hoffman et al.   GENETICS

Prevalence of transcription factors in ascomycete and basidiomycete fungi

(2014) Richard B Todd et al.   BMC GENOMICS

Translational control of immune responses: from transcripts to translatomes

(2014) Ciriaco A Piccirillo et al.   NATURE IMMUNOLOGY

Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression

(2014) Hiroyuki Hiraishi et al.   NUCLEIC ACIDS RESEARCH

New roles of the fission yeast eIF2  kinases Hri1 and Gcn2 in response to nutritional stress

(2013) R. Martin et al.   JOURNAL OF CELL SCIENCE

The Transcription Factors Atf1 and Pcr1 Are Essential for Transcriptional Induction of the Extracellular Maltase Agl1 in Fission Yeast

(2013) Hiroaki Kato et al.   PLoS One

Mechanisms of translational regulation by a human eIF5-mimic protein

(2011) Chingakham Ranjit Singh et al.   NUCLEIC ACIDS RESEARCH

How do tumours adapt to nutrient stress?

(2010) Ronald C Wek et al.   EMBO JOURNAL

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

(2010) Jiangbin Ye et al.   EMBO JOURNAL

The Roles of Stress-Activated Sty1 and Gcn2 Kinases and of the Protooncoprotein Homologue Int6/eIF3e in Responses to Endogenous Oxidative Stress during Histidine Starvation

(2010) Naoki Nemoto et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolutionary Roles of Upstream Open Reading Frames in Mediating Gene Regulation in Fungi

(2009) Heather M. Hood et al.   Annual Review of Microbiology

An Upstream Open Reading Frame Regulates Translation of GADD34 during Cellular Stresses That Induce eIF2α Phosphorylation

(2009) Yun-Young Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Int6/eIF3e Promotes General Translation and Atf1 Abundance to Modulate Sty1 MAPK-dependent Stress Response in Fission Yeast

(2008) Tsuyoshi Udagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY